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김명희 교수

Kim Myung-hee

경희대학교 진단검사의학과 · 의학

연구실 소개

김명희 교수의 연구실은 감염성 질환의 조기 진단과 내성 세균의 분자적 특성 규명을 핵심으로 삼고 있습니다. 특히 혈액에서의 프로칼цит론성 단백질(PCT) 수치를 활용한 세균성 혈행감염 진단, BK 바이러스 관련 미크로RNA를 이용한 신장병 진단 마커 개발, 그리고 메트로니다이드 내성 등 다제내성 세균의 유전자적 특성 분석을 중심으로 연구를 진행하고 있습니다. 최근에는 뇌졸중 등 신경질환의 혈액 생체마커 탐색을 통해 빠른 진단을 위한 기반을 마련하고 있습니다.

생체마커항생제 내성바이러스 감염분자진단다제내성 세균

연구 현황

논문 수
81
총 인용 수
862
최근 5년 논문
12
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
12총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
19총합
20212022202320242025

주요 논문

15
1
논문|인용수 80·2011
Utility of Procalcitonin as an Early Diagnostic Marker of Bacteremia in Patients with Acute Fever
Myeong Hee Kim, Ga‐Young Lim, So Young Kang, Wooin Lee, Jin‐Tae Suh, Hee Joo Lee
SJR Q2Yonsei Medical JournalOA

In febrile patients, elevated PCT may help predict bacteremia; furthermore, low PCT levels were helpful for ruling out bacteremia as a diagnosis. Therefore, PCT assessment could help physicians limit the number of prescriptions for antibiotics.

EpidemiologyMedicine
2
논문|인용수 61·2017
Urinary exosomal viral microRNA as a marker of BK virus nephropathy in kidney transplant recipients
Myeong Hee Kim, Yu Ho Lee, Jung-Woo Seo, Haena Moon, Jin Sug Kim, Yang‐Gyun Kim, Kyung Hwan Jeong, Ju-Young Moon, Tae Won Lee, Chun‐Gyoo Ihm, Chan‐Duck Kim, Jae Berm Park
SJR Q1PLoS ONEOA

This study suggests that urinary exosomal bkv-miR-B1-5p and bkv-miR-B1-5p/miR-16 could be surrogate markers for the diagnosis of BKVN.

OncologyMedicine
3
논문|인용수 46·2010
Molecular Characteristics of Extended Spectrum β-Lactamases inEscherichia coliandKlebsiella pneumoniaeand the Prevalence ofqnrin Extended Spectrum β-Lactamase Isolates in a Tertiary Care Hospital in Korea
Myeong Hee Kim, Hee Joo Lee, Kyung Park, Jin Tae Suh
SJR Q2Yonsei Medical JournalOA

PURPOSE: Extended spectrum beta-lactamases (ESBLs) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. In addition, the quinolone resistance qnr genes are becoming increasingly prevalent in clinical isolates, some of which also produce ESBL. This study was designed to evaluate the occurrence and genotypic distribution of ESBL producing Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) as well as the

Molecular MedicineBiochemistry, Genetics and Molecular Biology
4
논문|인용수 35·2010
Plasma biomarkers in the diagnosis of acute ischemic stroke.
Myeong Hee Kim, So Young Kang, Myung Chun Kim, Woo In Lee
PubMed

Rapid diagnosis and timely treatment improves the outcome in patients with ischemic stroke, but a rapid and sensitive blood test for ischemic stroke does not exist. This study tested whether a panel of biomarkers might be useful in the diagnosis of acute ischemic stroke. Consecutive patients with suspected stroke presenting to the emergency department of a university hospital in Korea were enrolled. Plasma specimens were assayed for brain natriuretic peptide, D-dimer, matrix metalloproteinase-9,

EpidemiologyMedicine
5
논문|인용수 27·2010
Molecular Characteristics of Extended Spectrum β-Lactamases in Escherichia coli and Klebsiella pneumoniae and the Prevalence of qnr in Extended Spectrum β-Lactamase Isolates in a Tertiary Care Hospital in Korea
김명희, 박경선, 서진태, 이희주
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120100510050768

Purpose: Extended spectrum β-lactamases (ESBLs) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. In addition, the quinolone resistance qnr genes are becoming increasingly prevalent in clinical isolates, some of which also produce ESBL. This study was designed to evaluate the occurrence and genotypic distribution of ESBL producing Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae)as well as the pre

6
논문|인용수 20·2013
Evaluation of a new rapid test kit to detect hepatitis C virus infection
Myeong Hee Kim, So Young Kang, Woo In Lee
SJR Q3Journal of Virological Methods
HepatologyMedicine
7
논문|인용수 20·2017
Occult HBV among Anti-HBc Alone: Mutation Analysis of an HBV Surface Gene and Pre-S Gene
Myeong Hee Kim, So Young Kang, Woo In Lee
SJR Q2Yonsei Medical JournalOA

PURPOSE: The aim of this study is to investigate the molecular characteristics of occult hepatitis B virus (HBV) infection in 'anti-HBc alone' subjects. MATERIALS AND METHODS: Twenty-four patients with 'anti-HBc alone' and 20 control patients diagnosed with HBV were analyzed regarding S and pre-S gene mutations. All specimens were analyzed for HBs Ag, anti-HBc, and anti-HBs. For specimens with an anti-HBc alone, quantitative analysis of HBV DNA, as well as sequencing and mutation analysis of S a

EpidemiologyMedicine
8
논문|인용수 16·2011
기능성화장품 구매성향에 따른 소비자 만족도 -미백개선제, 자외선차단제, 주름개선제-
김명희, 황춘섭
아시안뷰티화장품학술지

The purposes of this study were to analyse the factors of shopping orientation of cosmeceuticals, to classify women consumers according to their shopping orientation of cosmeceuticals, and to investigate the differences in the level of satisfaction with cosmeceuticals among the groups classified according to their shopping orientation of cosmeceuticals. The study was implemented through a descriptive survey method using a questionnaire. Subjects were 1258 women in their 20's-60's residing in Seo

9
논문|인용수 14·2017
Misidentification of Acinetobacter baumannii as Alcaligenes faecalis by VITEK 2 System; Case Report
Suekyeung Kim, Myeong Hee Kim, Woo In Lee, So Young Kang, You La Jeon
SJR Q3Laboratory MedicineOA

Acinetobacter baumannii (A. baumannii) is widely known as an opportunistic bacterial pathogen that causes infection more frequently among immunocompromised individuals. Our case demonstrated the limitation of the current VITEK 2 system for the idendification of A. baumannii. Four clinical isolates of A. baumannii were identified as Alcaligenes faecalis by the VITEK 2 system. Misidentification might lead to unnecessary tests and inappropriate treatments. Additional methods appear to be helpful fo

Molecular MedicineBiochemistry, Genetics and Molecular Biology
10
논문|인용수 14·2013
Detection of Methicillin-ResistantStaphylococcus aureusin Healthcare Workers Using Real-Time Polymerase Chain Reaction
Myeong Hee Kim, Woo In Lee, So Young Kang
SJR Q2Yonsei Medical JournalOA

Healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have recently become an important issue for healthcare facilities due to high rates of infection, mortality, and high treatment costs. We investigated the frequency of MRSA in healthcare workers (HCWs) via nasal carriage and assessed the performance of the LightCycler® MRSA Advanced test. We tested nasal swabs from the anterior nares of participating HCWs at an intensive care unit. Nasal swabs were iden

Infectious DiseasesMedicine
11
논문|인용수 11·2005
A Case of Chromobacterium Infection after Car Accident in Korea
Myeong Hee Kim, Hee Joo Lee, Jin Tae Suh, Boo Soon Chang, Kyu Seok Cho
SJR Q2Yonsei Medical JournalOA

Chromobacterium violaceum is a gram negative straight rod, 0.8-1.2 by 2.5 to 6.0 m, which is motile by one polar flagella and one to four lateral flagella. The organism inhabits soil and water and is often found in semitropical and tropical climates. Infections in humans are rare. We report a case of infection caused by strains of C. violaceum. A 38-year-old male patient was admitted to KyungHee University Hospital, Seoul, Korea on July 28th, 2003, after a car accident. The patient had multiple

BiotechnologyBiochemistry, Genetics and Molecular Biology
12
논문|인용수 9·2013
기능성 화장품 쇼핑성향이 상표전환 동기에 미치는 영향
김명희, 황춘섭

This study obtains information required for a comprehensive understanding of the brand-switching behavior by cosmetics consumers and for the establishment of effective strategies to make customers more loyal to the company. The study examines the relationships between customer shopping orientation and brand switching motives with respect to cosmeceuticals. A descriptive survey method using a self-administered questionnaire was employed. The sample consisted of 1,258 females between the ages of 2

13
letter|인용수 7·2015
Optimum initial loading dose of vancomycin for pneumonia caused by methicillin-resistant Staphylococcus aureus
You La Jeon, Myeong Hee Kim, Hyung‐Seok Yang, So Young Kang, Woo In Lee
SJR Q1Journal of Infection
Infectious DiseasesMedicine
14
논문|인용수 7·2020
Etest Methods for Screening Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA) strains
Min Young Lee, Woo In Lee, Myeong Hee Kim, So Young Kang, Young Jin Kim
SJR Q2Current Microbiology
Infectious DiseasesMedicine
15
논문|인용수 7·2008
Comparison of In-house PCR with Conventional Techniques and Cobas Amplicor M. tuberculosis™ Kit for Detection of Mycobacterium tuberculosis
김명희, 양희영, 서진태, 이희주

Purpose: Polymerase chain reaction (PCR) assay, introduced as a fast and sensitive diagnostic method, is useful in detecting Mycobacterium tuberculosis. The purpose of this study was to evaluate the usefulness of in-house PCR assay in the detection of Mycobacterium tuberculosis by comparing PCR results with conventional diagnostic techniques and Cobas Amplicor M. tuberculosis™ kit. Materials and Methods: We retrospectively assessed the diagnostic yield of in-house PCR method employed for the amp

대표 연구 분야

EpidemiologyInfectious DiseasesSurgeryHepatologyRheumatologyHematology

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