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서관식 교수

Kwan Sik Seo

서울대학교 재활의학과 · 의학

연구실 소개

서관식 교수의 연구실은 유방암 치료 후 유병하는 상지 운동 기능 장애와 림프부종의 발생 원인 및 치료 전략을 중심으로 연구를 진행하고 있습니다. 특히 복합적 림프부종 치료(CDT), 심부신경 차단(SGB), 수술적 재건 수술 등 비약물적 치료법의 효과를 정량적으로 평가하며, 환자의 삶의 질 향상과 기능 회복에 초점을 맞추고 있습니다. 림프관 단층촬영을 활용한 개인 맞춤형 치료 전략 수립도 핵심 과제로 삼고 있습니다.

유방암 관련 림프부종복합적 림프부종 치료심부신경 차단운동 기능 장애삶의 질 평가

연구 현황

논문 수
81
총 인용 수
1,234
최근 5년 논문
15
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
15총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
60총합
20212022202320242025

주요 논문

15
1
논문|인용수 141·2009
Longitudinal change of treatment‐related upper limb dysfunction and its impact on late dysfunction in breast cancer survivors: A prospective cohort study
Eun Joo Yang, Won‐Beom Park, Kwan Sik Seo, Sung‐Won Kim, Chan Yeong Heo, Jae‐Young Lim
SJR Q1Journal of Surgical OncologyOA

BACKGROUND AND OBJECTIVES: To investigate the prevalence of upper limb dysfunction (ULD) and subtypes after breast cancer surgery and to identify factors associated with late ULD. METHODS: Among 191 enrolled patients, 191 were evaluated at 3 months, 187 at 6 months, and 183 at 12 months after surgery. Pain, shoulder range of motion, muscle strength, and arm circumference were assessed. Based on symptoms and physical examinations, the types of ULD common after breast cancer treatment were diagnos

OncologyMedicine
2
논문|인용수 118·2005
Comparison of discographic findings in asymptomatic subject discs and the negative discs of chronic LBP patients: Can discography distinguish asymptomatic discs among morphologically abnormal discs?
Richard Derby, Byung‐Jo Kim, Sang‐Heon Lee, Yung Chen, Kwan Sik Seo, Charles N. Aprill
SJR Q1The Spine Journal
PharmacologyMedicine
3
논문|인용수 113·2004
Complications following cervical epidural steroid injections by expert interventionalists in 2003.
Richard Derby, Sang‐Heon Lee, Byung‐Jo Kim, Yung Chen, Kwan Sik Seo
PubMed

BACKGROUND: Two major portals are available for delivery of medication into the cervical epidural space: interlaminar and transforaminal. The choice of which approach to use is commonly made by assessing the patient's structural pathology, one's skill in performing each procedure, and then weighing the advantages versus the risk associated with the particular technique. Over the past several years, a growing number of cases involving serious complications following cervical transforaminal epidur

Pathology and Forensic MedicineMedicine
4
논문|인용수 82·2012
Quality of Life, Upper Extremity Function and the Effect of Lymphedema Treatment in Breast Cancer Related Lymphedema Patients
Ji Eung Park, Hye Jin Jang, Kwan Sik Seo
SJR Q1Annals of Rehabilitation MedicineOA

OBJECTIVE: To evaluate quality of life (QOL), upper extremity function and the effect of lymphedema treatment in patients with breast cancer related lymphedema. METHOD: The basic data comprised medical records (detailing age, sex, dominant side, location of tumor, cancer stage, operation record, cancer treatment and limb circumferences) and questionnaires (lymphedema duration, satisfaction, self-massage). Further to this, we measured upper extremity function and QOL, administered the DASH (Disab

OncologyMedicine
5
논문|인용수 72·2005
Single-level lumbar fusion in chronic discogenic low-back pain: psychological and emotional status as a predictor of outcome measured using the 36-item Short Form
Richard Derby, John J. Lettice, Thomas A. Kula, Sang‐Heon Lee, Kwan Sik Seo, Byung‐Jo Kim
SJR Q1Journal of Neurosurgery Spine

OBJECT: The authors examined the effect of psychological and emotional status on the outcome in patients with suspected chronic discogenic low-back pain (LBP) who have undergone lumbar fusion. METHODS: The authors retrospectively analyzed the medical records, including the results of the 36-item Short Form (SF-36), of 57 consecutive patients (mean age 42.7 years) who underwent single-level lumbar reconstructive surgery between 1994 and 2000. The SF-36 physical component summary (PCS) and mental

Pathology and Forensic MedicineMedicine
6
논문|인용수 56·2006
In vitro measurement of pressure differences using manometry at various injection speeds during discography
Kwan Sik Seo, Richard Derby, Elaine S. Date, Sang‐Heon Lee, Byung‐Jo Kim, Sang‐Heon Lee
SJR Q1The Spine Journal
PharmacologyMedicine
7
논문|인용수 52·2005
The Relation Between Annular Disruption on Computed Tomography Scan and Pressure-Controlled Diskography
Richard Derby, Byung‐Jo Kim, Yung Chen, Kwan Sik Seo, Sang‐Heon Lee
SJR Q1Archives of Physical Medicine and Rehabilitation
Pathology and Forensic MedicineMedicine
8
논문|인용수 45·2004
In vitro measurement of pressure in intervertebral discs and annulus fibrosus with and without annular tears during discography
Sang‐Heon Lee, Richard Derby, Yung Chen, Kwan Sik Seo, Mi Jung Kim
SJR Q1The Spine Journal
Pathology and Forensic MedicineMedicine
9
논문|인용수 16·2018
Comparison Between the Effectiveness ofComplex Decongestive Therapy and StellateGanglion Block in Patients with BreastCancer-Related Lymphedema: A RandomizedControlled Study
Kwan Sik Seo
SJR Q1Pain PhysicianOA

Background: Breast cancer-related lymphedema (BCRL) of the upper extremities often follows breast cancer treatment. Although complex decongestive therapy (CDT) is currently the standard treatment for BCRL, stellate ganglion block (SGB) has also been reported to be effective. Objectives: This study aimed to determine the effectiveness of SGB in the treatment of BCRL, and to assess the impact of the treatment on the quality of life (QoL) compared to CDT. Study Design: A randomized controlled trial

OncologyMedicine
10
논문|인용수 16·2008
The Influence of Psychologic Factors on Diskography in Patients With Chronic Axial Low Back Pain
Richard Derby, Sang‐Heon Lee, Yung Chen, Byung‐Jo Kim, Sang‐Heon Lee, Young Ki Hong, Jeong Eun Lee, Kwan Sik Seo
SJR Q1Archives of Physical Medicine and Rehabilitation
PharmacologyMedicine
12
논문|인용수 10·2019
The New Possibility of Lymphoscintigraphy to Guide a Clinical Treatment for Lymphedema in Patient With Breast Cancer
Kwan Sik Seo, Minseok Suh, Sunmok Hong, Gi Jeong Cheon, Shi-Uk Lee, Gwang Pyo Jung
SJR Q2Clinical Nuclear Medicine

OBJECTIVES: Lymphedema is a chronic disease that occurs frequently after breast cancer treatment. For the treatment of lymphedema, surgical approach such as vascularized lymph node transfer and super-microscopic lymphovenous anastomosis surgery is well established. Complex decongestive therapy (CDT) and sympathetic ganglion block (SGB) are two non-surgical therapeutic options. This study aimed to evaluate the effectiveness of lymphoscintigraphy in guiding the selection of the optimal non-surgica

OncologyMedicine
13
논문|인용수 9·2022
What Should We Focus on When Managing Breast Cancer-Related Lymphedema to Improve Quality of Life?
Hyun‐Sung Lee, Hyun Jeong Lee, Kwan Sik Seo
SJR Q2Lymphatic Research and Biology

Background: Breast cancer-related lymphedema (BCRL) is correlated with poor quality of life (QOL). The effects of the management of lymphedema on QOL remain controversial. We analyzed the changes in QOL and identified factors associated with its improvement to improve the care of patients with BCRL. Methods and Results: A total of 194 patients with BCRL were recruited, and their medical records were reviewed regarding type of surgery, chemotherapy, and radiation. Patients completed the European

OncologyMedicine
14
논문|인용수 7·2019
The importance of physical function in patients with multiple myeloma for improving quality of life
Shin Hoo Kim, Inho Kim, Youngil Koh, Dong‐Yeop Shin, Joonsik Hong, Kwan Sik Seo
SJR Q1Supportive Care in Cancer
HematologyMedicine
15
논문|인용수 5·2023
Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine
Mi-Rae ‍Park, Hye-Jin Lee, Hyemin Jang, Nam Hoon Kim, Jun‐Seok Lee, Yong Taek Jeong, In-Ho Kim, Sang-Hyun Choi, Kwan Sik Seo, Dong‐Hoon Kim
SJR Q1Journal of Lipid ResearchOA

Chemotherapy-induced cachexia causes severe metabolic abnormalities independently of cancer and reduces the therapeutic efficacy of chemotherapy. The underlying mechanism of chemotherapy-induced cachexia remains unclear. Here we investigated the cytarabine (CYT)-induced alteration in energy balance and its underlying mechanisms in mice. We compared energy balance-associated parameters among the three groups of mice: CON, CYT, and PF (pair-fed mice with the CYT group) that were intravenously admi

PhysiologyMedicine

대표 연구 분야

OncologyAtomic and Molecular Physics, and OpticsPathology and Forensic MedicineSurgeryPhysiologyPharmacology

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