김광우 교수

Our findings provide useful insights regarding RA genetic aetiology and variant-driven RA pathogenesis.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology that primarily affects women of childbearing age. The development of SLE is attributed to the breach of immunological tolerance and the interaction between SLE-susceptibility genes and various environmental factors, resulting in the production of pathogenic autoantibodies. Working in concert with the innate and adaptive arms of the immune system, lupus-related autoantibodies mediate immune-complex deposition i

OBJECTIVE: To define the interaction between cigarette smoking and HLA polymorphisms in seropositive rheumatoid arthritis (RA), in the context of a recently identified amino acid-based HLA model for RA susceptibility. METHODS: We imputed Immunochip data on HLA amino acids and classical alleles from 3 case-control studies (the Swedish Epidemiological Investigation of Rheumatoid Arthritis [EIRA] study [1,654 cases and 1,934 controls], the Nurses' Health Study [NHS] [229 cases and 360 controls], an

The objective of this study is to improve the control performance of the radiant floor heating system in apart-ment buildings. For this, predictive control, which is simple and also compatible with the existing system, is suggested, and its performance is evaluated. The control system of radiant floor heating should be easily adapted to thermal mass characteristics and building load variations without complication in real application. In this study, predictive control using the ANN (Artificial N