주관중 교수

BACKGROUND/AIMS: This study evaluated the relationship between hyperuricemia and nonalcoholic fatty liver disease (NAFLD) by comparing the incidence rates of NAFLD in relation to serum uric acid levels in apparently healthy subjects during a 5-year period. METHODS: Among 15,638 healthy Korean subjects who participated in a health-screening program in 2003 and 2008, respectively, 4954 subjects without other risk factors were enrolled in this study. We compared the incidence rates of NAFLD in 2008

Erdafitinib prolonged RFS compared with intravesical chemotherapy in patients with papillary-only, high-risk NMIBC harboring FGFR alterations who had disease recurrence after BCG therapy and refused or were ineligible for radical cystectomy.

Elevated RDW is independently associated with advanced fibrosis in NAFLD.

OBJECTIVE: To investigate the effects of conventional and single port laparoscopically assisted vaginal hysterectomy (LAVH) on sexual function in premenopausal women. DESIGN: A prospective case-control study. SETTING: University teaching hospital. Population. A total of 95 premenopausal women having LAVH from January 2009 to December 2009. METHODS: Comparison of 47 premenopausal women who had single port LAVH using trans-umbilical GelPort access (SP-LAVH group) and 48 premenopausal women who had

PURPOSE: Despite recent improvements, resistance to traditional immunotherapy or chemotherapy is still common in patients with bladder cancer. We constructed an oncolytic virus from herpes simplex virus type II (HSV-2), which selectively targets tumor cells with an activated Ras signaling pathway. We evaluated the antitumor effect of this oncolytic HSV-2 (FusOn-H2) against bladder cancer, and compared with that of a first generation oncolytic virus derived from HSV-1 (Baco-1). MATERIALS AND METH

Purpose: In prostate cancer, the anti-apoptotic mechanism of sulfated glycoprotein-2 (clusterin) against tumor necrosis factor-alpha (TNF-α) receptors and the action of type 2 TNF-α receptor (TNFR2) were investigated. Materials and Methods: TNF-α, agonistic-TNF type 1 receptor (TNFR1) antibody, agonistic-TNF-R2 antibody and their combination were treated in PC3 cell line with or without anti-clusterin. Cytotoxicity was assessed by trypan blue dye exclusion assay. By using flowcytometric analysis

= Abstract = Purpose: We investigated the predictive factors in patient with prostate cancer diagnosed by repeat prostate biopsy, where initial prostate biopsy results were negative for malignancy. Materials and Methods: Between March 2000 and June 2007, 1280 men with suspected prostatic cancer underwent transrectal ultrasound guided needle biopsy of the prostate, with 148 (11.6%) diagnosed as having prostate cancer. Of 1132 men whose biopsy results were negative for malignancy, 655 whose prosta

Purpose: We investigated the predictive factors in patient with prostate cancer diagnosed by repeat prostate biopsy, where initial prostate biopsy results were negative for malignancy. Materials and Methods: Between March 2000 and June 2007, 1280 men with suspected prostatic cancer underwent transrectal ultrasound guided needle biopsy of the prostate, with 148 (11.6%) diagnosed as having prostate cancer. Of 1132 men whose biopsy results were negative for malignancy, 655 whose prostate specific a

=Preliminary Study of Effects of Type V Phosphodiesterase Inhibitor (Vardenafil) on Oxytocin Expression in the Rat Paraventricular Nucleus Kwan Joong Joo, Heung Jae Park and Khae Hawn Kim

You have accessJournal of Urology1 Apr 2008THERAPEUTIC EFFECT ON BLADDER CANCER WITH A CONDITIONALLY REPLICATING ONCOLYTIC VIRUS DERIVED FROM HERPES SIMPLEX VIRUS TYPE II Kwan Joong Joo, Hideyuki Yamashita, Hongtao Li, Xiaoliu Zhang, and Seth P Lerner Kwan Joong JooKwan Joong Joo More articles by this author , Hideyuki YamashitaHideyuki Yamashita More articles by this author , Hongtao LiHongtao Li More articles by this author , Xiaoliu ZhangXiaoliu Zhang More articles by this author , and Seth P