민경하 교수

INTRODUCTION: Young adults receive health screenings at lower rates than other age groups, and it may be difficult to detect diseases in the early stages for this group. We examined differences in health status relative to smoking in a young age group using the results of health screenings conducted in engaged and newly married couples in a cross-sectional database. METHODS: The participants in this study were 808 young adults who visited a municipal hospital health screening center from July 20

BACKGROUND: Limited information is available about the present characteristics and dynamic clinical changes that occur in patients with COVID-19 during the early phase of the illness. OBJECTIVE: This study aimed to develop and validate machine learning models based on clinical features to assess the risk of severe disease and triage for COVID-19 patients upon hospital admission. METHODS: This retrospective multicenter cohort study included patients with COVID-19 who were released from quarantine

Abstract Significant associations between air pollution (AP) and insulin resistance (IR) have been reported in limited populations or certain patient groups, but few studies have addressed this association in the general population, especially in Asians. Although abdominal fat is a major contributor to IR, previous studies have not fully controlled for its effect in the association between AP and IR. We investigated the association between exposure to AP and IR in Korean adults in the general po

Blood urea nitrogen (BUN) to albumin ratio (BAR) is a comprehensive parameter that reflects renal, inflammatory, nutritional, and endothelial functions. BAR has been shown to be associated with various cancers, pneumonia, sepsis, and pulmonary and cardiovascular diseases; however, few studies have been conducted on its association with cerebrovascular diseases. In this study, we evaluated the association between BAR and cerebral small vessel disease (cSVD) in health check-up participants. We ass

Abstract Background Inflammation is a major pathological mechanism underlying cerebrovascular disease. Recently, a new inflammatory marker based on the ratio between monocyte count and high-density lipoprotein (HDL) cholesterol has been proposed. In this study, we evaluated the relationship between monocyte-to-HDL cholesterol ratio (MHR) and cerebral small vessel disease (cSVD) lesions in health check-up participants. Methods This study was a retrospective cross-sectional study based on a regist

Research on physical activity and health is actively being conducted. In the Korea National Health and Nutrition Examination Survey (KNHANES), the Global Physical Activity Questionnaire (GPAQ) was newly introduced in 2014. The purpose of this study was to investigate the levels of physical activity and related factors in Koreans who were assessed through the GPAQ by dividing the physical activity by occupation, leisure, and transport domain. This study used data from the KNHANES (2014KNHANES ( -

A higher PA level was associated with a lower prevalence and severity of total, voiding, and storage LUTS in a dose-dependent manner in Korean men.

Stroke and ischemic heart disease usually cause sudden death or disabilities.Therefore, early identification and risk management for high-risk groups are important.Cerebral small vessel diseases (cSVD) are known to lead to diseases such as stroke and dementia, 1 and asymptomatic coronary artery stenosis (CAS) is considered a subclinical condition of ischemic heart disease.Previous studies have demonstrated associations between stroke and asymptomatic CAS 2 and between cSVD and ischemic heart dis

Background: Glaceum Inc. has proposed HSG4112, a structural analogue of glabridin, as a novel anti-obesity compound. Animal studies and phase I human trials have shown that HSG4112 improves energy consumption, normalises weight, and is safe and drug-resistant. Based on these results, the company plans to conduct a phase 2a clinical trial to determine the safety and efficacy of HSG4112 in overweight and obese patients. Methods: A 16-week randomised, double-blind, placebo-controlled, parallel-grou

Abstract Background The high prevalence of coronary stenosis in patients with stroke is well established. However, the association between coronary stenosis and cerebral small vessel diseases (cSVD) in asymptomatic populations remains unclear. Methods As a cross-sectional study, we evaluated South Korean adults who underwent a health checkup including brain magnetic resonance imaging and coronary computed tomography angiography between January 2010 and December 2013. The degree of coronary steno

Red cell distribution width (RDW) is an indicator of red blood cell size heterogeneity and may reflect underlying chronic hypoxemia or inflammation. While RDW has been associated with the prognosis of various pulmonary and cardiovascular diseases, its relevance in cerebrovascular disease remains underexplored. In this study, we evaluated the association between RDW and cerebral small vessel disease (cSVD). We evaluated consecutive health check-up participants who underwent brain MRI between Janu

Background: Depression is associated with various physical conditions, including bone metabolism. Most previous studies were cross-sectional, and longitudinal findings regarding osteoporosis or fracture risk remain inconsistent. This study examined the association between mild depressive symptoms and annual changes in bone mineral density (BMD) among women undergoing repeated dual-energy X-ray absorptiometry (DEXA). Methods: We retrospectively analyzed 1,629 women aged ≥20 years who completed th