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한경화 교수

Kyung-Hwa Han

연세대학교 영상의학과 · 의학

연구실 소개

한경화 교수의 연구실은 영상의학 및 임상예측모델링 분야에서 핵심적인 연구를 수행하고 있습니다. 특히 영상자료를 기반으로 한 진단 및 예후 예측 모델 개발, AI 기반 영상 보고서의 정확성과 환자 친화성 향상, 그리고 MRI를 활용한 간세포암종 등 특정 질환의 영상 특징 분석에 중점을 두고 있습니다. 또한, 영상 해부학적 해석의 정확도를 높이기 위한 다독자 간 일치도 평가 및 생존 분석 기법의 적용 등 임상적 실용성을 강화하는 연구를 지속적으로 진행하고 있습니다.

임상예측모델AI 영상보고서MRI 영상해석예후분석다독자간 일치도

연구 현황

논문 수
412
총 인용 수
11,790
최근 5년 논문
125
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
125총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
1,369총합
20222023202420252026

주요 논문

15
1
리뷰|인용수 163·2016
How to Develop, Validate, and Compare Clinical Prediction Models Involving Radiological Parameters: Study Design and Statistical Methods
Kyunghwa Han, Kijun Song, Byoung Wook Choi
SJR Q1Korean Journal of RadiologyOA

Clinical prediction models are developed to calculate estimates of the probability of the presence/occurrence or future course of a particular prognostic or diagnostic outcome from multiple clinical or non-clinical parameters. Radiologic imaging techniques are being developed for accurate detection and early diagnosis of disease, which will eventually affect patient outcomes. Hence, results obtained by radiological means, especially diagnostic imaging, are frequently incorporated into a clinical

Radiology, Nuclear Medicine and ImagingMedicine
2
editorial|인용수 131·2022
Restricted Mean Survival Time for Survival Analysis: A Quick Guide for Clinical Researchers
Kyunghwa Han, Inkyung Jung
SJR Q1Korean Journal of RadiologyOA

In radiological research, survival analysis has been increasingly used to evaluate prognostic outcomes Researchers may be familiar with the use of Cox proportional hazards (PH) regression to quantify the effect of predictors, such as treatment, imaging, or radiological variables, using hazard ratios. Cox regression requires the proportional hazards assumption, which means that the ratio of hazards between groups is constant over the entire study period, to be valid; however, this scenario is rar

Economics and EconometricsEconomics, Econometrics and Finance
3
논문|인용수 76·2024
Patient-centered radiology reports with generative artificial intelligence: adding value to radiology reporting
Jiwoo Park, Kangrok Oh, Kyunghwa Han, Young Han Lee
SJR Q1Scientific ReportsOA

The purposes were to assess the efficacy of AI-generated radiology reports in terms of report summary, patient-friendliness, and recommendations and to evaluate the consistent performance of report quality and accuracy, contributing to the advancement of radiology workflow. Total 685 spine MRI reports were retrieved from our hospital database. AI-generated radiology reports were generated in three formats: (1) summary reports, (2) patient-friendly reports, and (3) recommendations. The occurrence

Health InformaticsMedicine
4
논문|인용수 25·2019
Imaging Features of Hepatocellular Carcinoma
Jinwoo Son, Shin Hwang, Sumi Park, Kyunghwa Han, Yong Eun Chung, Jin‐Young Choi, Myeong‐Jin Kim, Mi‐Suk Park
SJR Q1Investigative RadiologyOA

OBJECTIVES: The aim of this study was to compare the major imaging features of hepatocellular carcinoma (HCC) on magnetic resonance imaging (MRI) scans with Gd-EOB-DTPA (EOB) and extracellular agent (ECA; Gd-DTPA) contrast media. MATERIALS AND METHODS: Among 184 surgically proven HCCs in 169 patients who underwent a liver MRI with either EOB (n = 120) or ECA (n = 49), 55 HCCs were matched according to tumor size, Edmonson grade (major and worst), and gross type for each of the 2 contrast media.

HepatologyMedicine
5
editorial|인용수 24·2024
Statistical Methods for the Analysis of Inter-Reader Agreement Among Three or More Readers
Kyunghwa Han, Leeha Ryu
SJR Q1Korean Journal of RadiologyOA

The inter-reader agreement is a key imaging interpretation-related outcome parameter in radiological research.The interpretation of medical images can be affected by the subjective assessment of readers.Therefore, the measure of inter-reader agreement is crucial.A substantial degree of reliability is required in clinical research involving image interpretation.To evaluate the extent of inter-reader agreement, measures of agreement such as kappa, intraclass correlation coefficient (ICC), and conc

Statistics, Probability and UncertaintyDecision Sciences
6
논문|인용수 12·2017
1.5–2 cm tumor size was not associated with distant metastasis and mortality in small thyroid cancer: A population-based study
Kyunghwa Han, Eun‐Kyung Kim, Jin Young Kwak
SJR Q1Scientific ReportsOA

Most guidelines for the diagnosis and management of thyroid nodules have suggested fine-needle aspiration as a diagnostic tool, with some of these previously published guidelines suggesting a cutoff size of 1.5 cm. In thyroid cancers (1-2 cm), we hypothesized that tumors 1.5 cm or larger had more unfavorable clinical outcomes than ones smaller than 1.5 cm nodules. Using the Surveillance, Epidemiology, and End Results database, we identified 14,117 patients diagnosed with only primary thyroid can

Endocrinology, Diabetes and MetabolismMedicine
7
논문|인용수 11·2020
Strap muscle invasion in differentiated thyroid cancer does not impact disease-specific survival: a population-based study
Ja Kyung Yoon, Jandee Lee, Eun‐Kyung Kim, Jung Hyun Yoon, Vivian Youngjean Park, Kyunghwa Han, Jin Young Kwak
SJR Q1Scientific ReportsOA

TNM staging system of differentiated thyroid cancer defines gross strap muscle invasion as T3b stage. However, the impact of strap muscle invasion on disease-specific survival (DSS) remains controversial. To elucidate the survival impact of strap muscle invasion of any degree in thyroid cancers, the Surveillance, Epidemiology, and End Results (SEER) database (1973-2018) was queried for thyroid cancer only patients on July 2019 (n = 19,914). The Cox proportional hazard analysis with multivariable

Endocrinology, Diabetes and MetabolismMedicine
8
논문|인용수 11·2022
CT-based radiomics signature for differentiation between cardiac tumors and thrombi: a retrospective, multicenter study
Ji Won Lee, Chul Hwan Park, Dong Jin Im, Kye Ho Lee, Tae Hoon Kim, Kyunghwa Han, Jin Hur
SJR Q1Scientific ReportsOA

The study aimed to develop and validate whether the computed tomography (CT) radiomics analysis is effective in differentiating cardiac tumors and thrombi. For this retrospective study, a radiomics model was developed on the basis of a training dataset of 192 patients (61.9 ± 13.3 years, 90 men) with cardiac masses detected in cardiac CT from January 2010 to September 2019. We constructed three models for discriminating between a cardiac tumor and a thrombus: a radiomics model, a clinical model,

Cardiology and Cardiovascular MedicineMedicine
9
리뷰|인용수 4·2018
Trends in statistical methods in articles published in Archives of Plastic Surgery between 2012 and 2017
Kyunghwa Han, Inkyung Jung
SJR Q2Archives of Plastic SurgeryOA

This review article presents an assessment of trends in statistical methods and an evaluation of their appropriateness in articles published in the Archives of Plastic Surgery (APS) from 2012 to 2017. We reviewed 388 original articles published in APS between 2012 and 2017. We categorized the articles that used statistical methods according to the type of statistical method, the number of statistical methods, and the type of statistical software used. We checked whether there were errors in the

Statistics, Probability and UncertaintyDecision Sciences
10
논문|인용수 4·2015
Lesion stiffness measured by shear-wave elastography: Preoperative predictor of the histologic underestimation of US-guided core needle breast biopsy
Ah Young Park, Eun Ju Son, Jeong‐Ah Kim, Kyunghwa Han, Ji Hyun Youk
SJR Q1European Journal of RadiologyOA
Pathology and Forensic MedicineMedicine
11
논문|인용수 4·2024
Gadoxetic acid-enhanced MRI for the detection of liver metastases from melanoma
Hyun Jung Chung, Nieun Seo, Kyunghwa Han, Heejin Bae, Yong Eun Chung, Min Kyu Jung, Mi‐Suk Park
SJR Q1PLoS ONEOA

PURPOSE: We aimed to assess imaging findings and detection sensitivity for melanoma liver metastases on gadoxetic acid-enhanced magnetic resonance imaging (MRI). METHODS: This retrospective study included patients with melanoma liver metastasis who underwent gadoxetic acid-enhanced MRI. Two abdominal radiologists independently evaluated signal characteristics of liver metastases on morphologic imaging (precontrast T1- and T2-weighted imaging), diffusion-weighted imaging (DWI), dynamic imaging, a

OphthalmologyMedicine
12
논문|인용수 3·2022
Comparison of Coronary Computed Tomography Angiography Image Quality With High-concentration and Low-concentration Contrast Agents
Dong Jin Im, Yun‐Hyeon Kim, Ki Seok Choo, Joon‐Won Kang, Jung Im Jung, Yoo-Dong Won, Hyo Rim Kim, Myung Hee Chung, Kyunghwa Han, Byoung Wook Choi
SJR Q2Journal of Thoracic Imaging

PURPOSE: To confirm that the image quality of coronary computed tomography (CT) angiography with a low tube voltage (80 to 100 kVp), iterative reconstruction, and low-concentration contrast agents (iodixanol 270 to 320 mgI/mL) was not inferior to that with conventional high tube voltage (120 kVp) and high-concentration contrast agent (iopamidol 370 mgI/mL). MATERIALS AND METHODS: This prospective, multicenter, noninferiority, randomized trial enrolled a total of 318 patients from 8 clinical site

Radiology, Nuclear Medicine and ImagingMedicine
13
논문|인용수 3·2011
A Study of Relation Between Yamanaka Hardness and Penetrometer Cone Index
Kyunghwa Han, Hee-Rae Cho, Sang-Ho Jeon, Yong-Seon Zhang
Korean Journal of Soil Science and FertilizerOA

산중식 경도 (YA, MPa)와 관입식 경도 Cone index (PE, MPa) 의 측정치를 토양특성이 다른 16개 지점에서 비교해 본 결과, 다음과 같은 회귀식을 구할 수 있었다. <TEX>$$PE=YA^*1.80+0.16(R^2=0.91^{***},N=16)$$</TEX> 이 회귀식의 적용범위는 산중식경도 0.1 MPa 이상 1.3 MPa 이하, mm 단위로 8.0 mm 이상 24.5 mm 이하였다. This study was conducted in order to compare between Yamanaka hardness (YA), hand-push type, and penetrometer cone index (PE), on 16 upland sites. Yamanaka hardness had significant correlation with penetrometer cone index. The regression equation was <TEX>$PE=1.80^*YA+0.

Soil ScienceAgricultural and Biological Sciences
14
논문|인용수 2·2018
Water-dispersible Clay Content in Summer Rainy Season for Korean Irrigated Rice Paddy Fields as Affected by Cultivated Years Using Heavy Agro-machinery and Soil Properties
Kyunghwa Han
SJR Q4Korean Journal of Environmental AgricultureOA

Water-dispersible Clay Content in Summer Rainy Season for Korean Irrigated Rice Paddy Fields as Affected by Cultivated Years Using Heavy Agro-machinery and Soil Properties-Agro-machinery,Exchangeable sodium percentage,Middleton’s method,Paddy soil,Water-dispersibility of clay

Ecology, Evolution, Behavior and SystematicsAgricultural and Biological Sciences
15
논문|인용수 2·2018
Trends in statistical methods in articles published in Archives of Plastic Surgery between 2012 and 2017
한경화, 정인경

This review article presents an assessment of trends in statistical methods and an evaluation of their appropriateness in articles published in the Archives of Plastic Surgery (APS) from 2012 to 2017. We reviewed 388 original articles published in APS between 2012 and 2017. We categorized the articles that used statistical methods according to the type of statistical method, the number of statistical methods, and the type of statistical software used. We checked whether there were errors in the

대표 연구 분야

Radiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineEndocrinology, Diabetes and MetabolismGeneticsHepatologySurgery

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