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박경석 교수

Kyung Seok Park

서울대학교 신경과 · 의학

연구실 소개

박경석 교수의 연구실은 신경면역질환, 특히 수막하액(예: MOG-IgG, AQP4-IgG 관련 질환)의 임상적 특성과 예후에 대한 다기관 대규모 연구를 중심으로 진행되고 있습니다. 동시에 식물근권박테리아를 활용한 생물적 방제 및 시스템적 저항 유도 메커니즘에 대한 기초 및 응용 연구도 병행하고 있습니다. 특히 Bacillus vallismortis EXTN-1과 같은 PGPR 균주가 농작물의 병원균 저항성 향상과 수확량 증대에 기여하는 메커니즘을 규명하고 있습니다. 이는 농업 분야에서의 지속 가능한 병해충 관리 전략 개발에 기여하고 있습니다.

신경면역질환수막하액 항체식물근권박테리아생물방제시스템적 저항 유도

연구 현황

논문 수
208
총 인용 수
2,929
최근 5년 논문
36
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
36총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
272총합
20212022202320242025

주요 논문

15
1
논문|인용수 94·2021
Myelin Oligodendrocyte Glycoprotein-Immunoglobulin G in the CSF
Young Nam Kwon, Boram Kim, Jun‐Soon Kim, Heejung Mo, Kyomin Choi, Seong‐il Oh, Jee‐Eun Kim, Tai‐Seung Nam, Eun Hee Sohn, Sung Hyuk Heo, Sang Beom Kim, Key‐Chung Park
SJR Q1Neurology Neuroimmunology & NeuroinflammationOA

To investigate the clinical relevance of CSF myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) testing in a large multicenter cohort.

Pathology and Forensic MedicineMedicine
2
논문|인용수 51·2016
The incidence of and risk factors for ischemic complications after microsurgical clipping of unruptured middle cerebral artery aneurysms and the efficacy of intraoperative monitoring of somatosensory evoked potentials: A retrospective study
Hyoung Soo Byoun, Jae Seung Bang, Chang Wan Oh, O-Ki Kwon, Gyojun Hwang, Jung Ho Han, Tackeun Kim, Si Un Lee, Seong-Rae Jo, Dong‐Gun Kim, Kyung Seok Park
SJR Q2Clinical Neurology and Neurosurgery
NeurologyMedicine
3
논문|인용수 46·2008
Rhizobacterial exopolysaccharides elicit induced resistance on cucumber.
Kyung Seok Park, Joseph W. Kloepper, Choong‐Min Ryu
PubMed

The role of exopolysaccharides (EPSs) from a plant growth-promoting rhizobacterium, Burkholderia gladioli IN26, on elicitation of induced systemic resistance was investigated. A purified EPS induced expression of PR- 1a::GUS on tobacco and elicited induced resistance against Colletotrichum orbiculare on cucumber. The maximum level of disease protection was noted when seeds were soaked in 200 ppm of the EPS. Our results indicate that EPS from specific rhizobacteria can elicit induced resistance a

Plant ScienceAgricultural and Biological Sciences
4
논문|인용수 45·2016
Gender effect on neuromyelitis optica spectrum disorder with aquaporin4-immunoglobulin G
Sung‐Min Kim, Patrick Waters, Mark Woodhall, Yoo-Jin Kim, Jin-Ah Kim, So Young Cheon, Se‐Hoon Lee, Seong Rae Jo, Dong‐Gun Kim, Kyeong Cheon Jung, Kwang Woo Lee, Jung‐Joon Sung
SJR Q1Multiple Sclerosis Journal

BACKGROUND: Neuromyelitis optica spectrum disorder with aquaporin4-immunoglobulin G (NMOSD-AQP4) is an inflammatory disease characterised by a high female predominance. However, the effect of gender in patients with NMOSD-AQP4 has not been fully evaluated. OBJECTIVE: The aim of this study was to determine the effect of gender in clinical manifestations and prognosis of patients with NMOSD-AQP4. METHODS: The demographics, clinical and radiological characteristics, pattern reversal visual evoked p

Pathology and Forensic MedicineMedicine
5
논문|인용수 36·2007
Induced Systemic Resistance by Bacillus vallismortis EXTN-1 Suppressed Bacterial Wilt in Tomato Caused by Ralstonia solanacearum
Kyung Seok Park, Diby Paul, Yong‐Ki Kim, Ki‐Woong Nam, Young-Kee Lee, Hyo-Won Choi, Sang-Yeob Lee
SJR Q1The Plant Pathology JournalOA

Biocontrol activity of five strains of selected rhizo-bacteria were tested in tomato against bacterial wilt caused by Ralstonia solanacearum. After root bacterization the plants were grown in a perlite-hydroponic system. Upon challenge inoculation with the pathogen, all of the rhizobacterial strains efficiently suppressed the bacterial wilt in tomato in various rates, at maximum by the strain, Bacillus vallismortis strain EXTN-1. While the percent of infected plants in the non-bacterized control

Plant ScienceAgricultural and Biological Sciences
6
논문|인용수 31·2006
Bacillus vallismortis Strain EXTN-1 Mediated Systemic Resistance against Potato virus Y and X in the Field
Kyung Seok Park, Diby Paul, Kyung-Ryl Ryu, Eun-Yung Kim, Yong‐Ki Kim
SJR Q1The Plant Pathology JournalOA

Efficacy of plant growth promoting rhizobacteria(PGPR) Bacillus vallismortis strain EXTN-1 has been proved in eliciting induced systemic resistance(ISR) in several crops. The present paper described the beneficial effects of EXTN-1 in potato as increase in yield and chlorophyll content, and plant protection against Potato Virus Y and X(PVY & PVX). EXTN-1 induced systemic resistance to the plants resulting in significant disease suppression in the field. Also the plants under treatment with EXTN-

Plant ScienceAgricultural and Biological Sciences
7
논문|인용수 27·2011
Cerebrospinal fluid/serum gradient of IgG is associated with disability at acute attacks of neuromyelitis optica
Sung‐Min Kim, Patrick Waters, Angela Vincent, Min Jin Go, Kyung Seok Park, Jung‐Joon Sung, Kwang Woo Lee
SJR Q1Journal of Neurology
Pathology and Forensic MedicineMedicine
8
논문|인용수 27·2013
Factors Associated With the Time to Next Attack in Neuromyelitis Optica: Accelerated Failure Time Models With Random Effects
Sung-Min Kim, Jun‐Woo Park, Sun Hee Kim, Suyeon Park, Jee Young Kim, Jung‐Joon Sung, Kyung Seok Park, Kwang Woo Lee
SJR Q1PLoS ONEOA

The time to next attack in NMO can increase naturally in the later stages of the disease as the number of cumulative attacks increases. Nevertheless, both combined azathioprine treatment with continued oral prednisolone and rituximab treatment were also associated with a longer time to next attack, independently of the natural disease course of NMO.

Pathology and Forensic MedicineMedicine
9
논문|인용수 26·2012
Pattern-specific changes and discordant prognostic values of individual leg-muscle motor evoked potentials during spinal surgery
Sung‐Min Kim, Hyeran Yang, Soon-Bu Park, Suk Geun Han, Kun-Woo Park, Sang Hoon Yoon, Seung-Jae Hyun, Hyun-Jib Kim, Kyung Seok Park, Kwang‐Woo Lee
SJR Q1Clinical Neurophysiology
SurgeryMedicine
10
논문|인용수 26·2006
Bacillus vallismortis EXTN-1-Mediated Growth Promotion and Disease Suppression in Rice
Kyung Seok Park, Diby Paul, Wan-Hae Yeh
SJR Q1The Plant Pathology JournalOA

Bacillus vallismortis EXTN-1, a biocontrol agent in cucumber, tomato and potato was tested in rice pathosystem against rice fungal pathogens viz. Magnaporthe grisea, Rhizoctonia solani and Cochliobolus miyabeanus. Apart from increasing the yield in the bacterized plants (11.6-12.6% over control), the study showed that EXTN1 is effective in bringing about disease suppression against all the tested fungal pathogens. EXTN-l treatment resulted in 52.11% reduction in rice blast, 83.02% reduction in s

Plant ScienceAgricultural and Biological Sciences
11
논문|인용수 23·2015
Differences in Multimodality Intraoperative Neurophysiological Monitoring Changes Between Spinal Intramedullary Ependymoma and Hemangioblastoma
Dong‐Gun Kim, Yoo-Ri Son, Young-Seop Park, Seung-Jae Hyun, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim, Kyung Seok Park
SJR Q2Journal of Clinical Neurophysiology

In our study, the incidence of transient changes in MEPs was higher in hemangioblastoma than in ependymoma. Our data suggest that it may be necessary to consider tumor features and the type of surgical technique used, particularly when interpreting intraoperative neurophysiologic monitoring profiles of intramedullary spinal cord tumors such as ependymomas and hemangioblastomas.

SurgeryMedicine
12
논문|인용수 22·2019
Intraoperative neuromonitoring during microsurgical clipping for unruptured anterior choroidal artery aneurysm
Hyoung Soo Byoun, Chang Wan Oh, O-Ki Kwon, Si Un Lee, Seung Pil Ban, Sung Hoon Kim, Tackeun Kim, Jae Seung Bang, Sung Un Kim, Jongsuk Choi, Kyung Seok Park
SJR Q2Clinical Neurology and Neurosurgery
NeurologyMedicine
13
논문|인용수 20·2021
Neurophysiological monitoring during anterior cervical discectomy and fusion for ossification of the posterior longitudinal ligament
Jee-Eun Kim, Jun-Soon Kim, Sejin Yang, Jongsuk Choi, Seung-Jae Hyun, Ki-Jeong Kim, Kyung Seok Park
SJR Q2Clinical Neurophysiology PracticeOA

The utility of IONM in ACDF for OPLL has not been evaluated due to its rarity. This study supports the use of IONM in cervical OPLL with myelopathy.

SurgeryMedicine
14
논문|인용수 19·2014
Characterization of the spectrum of Korean inflammatory demyelinating diseases according to the diagnostic criteria and AQP4-Ab status
Sung‐Min Kim, Patrick Waters, Mark Woodhall, Ji Won Yang, Hyeran Yang, Jee‐Eun Kim, Jung‐Joon Sung, Kyung Seok Park, Kwang Woo Lee
SJR Q2BMC NeurologyOA

BACKGROUND: The relative frequencies of demyelinating diseases among Korean patients with idiopathic inflammatory demyelinating disease of the central nervous system (IIDD) have not been sufficiently studied. We therefore describe a cohort of 203 patients with IIDD from three centers in Korea whose syndromes were identified precisely according to international clinical criteria and autoantibody to aquaporin 4 (AQP4-Ab) status. METHODS: In total, 260 consecutive patients were screened and 203 wer

Pathology and Forensic MedicineMedicine
15
논문|인용수 19·2016
Accuracy of the Fluorescence-Activated Cell Sorting Assay for the Aquaporin-4 Antibody (AQP4-Ab): Comparison with the Commercial AQP4-Ab Assay Kit
Jiwon Yang, Sungmin Kim, Yoo-Jin Kim, So Young Cheon, Boram Kim, Kyeong Cheon Jung, Kyung Seok Park
SJR Q1PLoS ONEOA

Both the FACS assay and C-CBA are sensitive and highly specific assays in detecting AQP4-Ab. However, in some sera with relatively low antibody titer, FACS-assay can be a more sensitive assay option. In real practice, complementary use of FACS assay and C-CBA will benefit the diagnosis of NMO patients, because the former can be more sensitive among low titer sera and the latter are easier to use therefore can be widely used.

Molecular BiologyBiochemistry, Genetics and Molecular Biology

대표 연구 분야

NeurologyPathology and Forensic MedicineSurgeryPlant ScienceMolecular BiologyRadiology, Nuclear Medicine and Imaging

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