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고경아 교수

Kyung‐A Ko

연세대학교 치주과 · 치의학

연구실 소개

고경아 교수의 연구실은 치과 임플란트 및 뼈 재생 분야에서 주로 활동하며, 특히 치아 결손 후 릉드 복원을 위한 가이드드 뼈 재생(GBR) 기법과 혈소판 농축 혈장(프리피어드 린프, PRF)의 응용에 초점을 맞추고 있습니다. 다양한 동물 모델(비염개)과 임상 연구를 통해 뼈 대체재, 생체막의 고정 방식, 조직 재생 메커니즘을 정량적으로 분석하고 있으며, 치료의 안정성과 환자 중심의 결과(예: 환자 보고 결과, 임상적 안정성)를 동시에 고려한 종합적 접근을 펼치고 있습니다. 특히, 조직학적 분석과 고해상도 CT 촬영을 융합한 정밀한 재생 평가 기법을 개발·적용하고 있습니다.

뼈 재생가이드드 뼈 재생PRF임플란트조직 재생

연구 현황

논문 수
21
총 인용 수
333
최근 5년 논문
13
주요 분야
치의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
13총합
2021
2022
2024
2025
2026
5개년 연도별 피인용 수
123총합
20212022202420252026

주요 논문

15
1
논문|인용수 97·1990
Systematic variation in myosin expression along extraocular muscle fibres of the adult rat
J. Jacoby, Kyung‐A Ko, C. Weiß, Julie Ivory Rushbrook
SJR Q3Journal of Muscle Research and Cell Motility
NeurologyNeuroscience
2
논문|인용수 56·1994
Identification of alpha-cardiac myosin heavy chain mRNA and protein in extraocular muscle of the adult rabbit
Julie Ivory Rushbrook, C. Weiß, Kyung‐A Ko, Miriam H. Feuerman, Stephen Carleton, A. Ing, J. Jacoby
SJR Q3Journal of Muscle Research and Cell Motility
Cardiology and Cardiovascular MedicineMedicine
3
논문|인용수 25·2022
Effect of collagen membrane fixation on ridge volume stability and new bone formation following guided bone regeneration
Jin‐Young Park, Young Woo Song, Kyung‐A Ko, Franz Josef Strauß, Daniel S. Thoma, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: To test the effect of membrane fixation on ridge volume stability and new bone formation using guided bone regeneration. MATERIALS AND METHODS: In eight beagle dogs, after bilateral extraction of the maxillary pre-molars, a box-shaped defect was created on each side. All defect sites were augmented with a particulate bone substitute material, covered with either one of two non-cross-linked collagen membranes (CM1 or CM2) with or without fixation (-F or -UF). Samples were collected after 8 w

UrologyMedicine
4
논문|인용수 24·2021
Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial
Jin‐Young Park, Kyung‐A Ko, Jiyeong Lee, Yoogyeong Oh, Hyun‐Chang Lim, Dong‐Woon Lee, Seong‐Ho Choi, Jae‐Kook Cha
SJR Q1NutrientsOA

BACKGROUND: Mangosteen and propolis extracts (MAEC) have been potential therapeutic agents known to exhibit powerful antioxidant and anti-inflammatory properties. The aim of the current study was to evaluate the clinical and immunological efficacy of MAEC as well as safety and patient-reported outcomes (PROMs) on gingivitis and incipient periodontitis. METHODS: This study was performed on 104 patients diagnosed with gingivitis or incipient periodontitis. At baseline, the participants were random

Insect ScienceAgricultural and Biological Sciences
5
논문|인용수 24·1993
Sarcoplasmic reticulum fast CA(2+)-pump and myosin heavy chain expression in extraocular muscles.
J. Jacoby, Kyung‐A Ko
PubMed

PURPOSE: To investigate the distribution of the sarcoplasmic reticulum fast-twitch Ca(2+)-pump (Ca(2+)-adenosine triphosphatase [Ca(2+)-ATPase]) in extraocular muscle fiber populations of the rat and rabbit, using fast Ca(2+)-adenosine triphosphatase-specific monoclonal antibodies. METHODS: Adult female rats and rabbits were killed with overdose of sodium pentobarbital, and the extraocular muscles were rapidly frozen in isopentane cooled with liquid nitrogen. Serial transverse frozen sections we

RheumatologyMedicine
6
논문|인용수 15·2022
Platelet‐rich fibrin combined with a particulate bone substitute versus guided bone regeneration in the damaged extraction socket: An in vivo study
Jin‐Young Park, Kyu‐Jin Hong, Kyung‐A Ko, Jae‐Kook Cha, Reinhard Gruber, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: It has been proposed that platelet-rich fibrin (PRF) can be used to support bone regeneration during alveolar ridge augmentation. The aim of this study was to determine whether an approach utilizing PRF provides similar performance to the established guided bone regeneration (GBR) procedure. MATERIALS AND METHODS: Two-wall defects were surgically created in beagle dogs and treated in three experimental groups: (i) a sticky bone (SB) substitute prepared using liquid PRF and deproteinized por

UrologyMedicine
7
논문|인용수 15·2020
Changes in mucogingival junction after an apically positioned flap with collagen matrix at sites with or without previous guided bone regeneration: A prospective comparative cohort study
Kyung‐A Ko, Jung‐Seok Lee, Jang‐Hyun Kim, Ji‐Man Park, Reinhard Gruber, Daniel S. Thoma
SJR Q1Clinical Oral Implants ResearchOA

AIM: To assess changes in the position of the mucogingival junction (MGJ) after an apically positioned flap (APF) with collagen matrix performed at sites with or without previous guided bone regeneration (GBR). MATERIALS AND METHODS: Dental implants were placed with or without GBR (group GBR or non-GBR) depending on the available ridge width in 30 patients with a limited width of keratinized mucosa (MGJ placed more coronally than the expected prosthetic margin). An apically positioned flap with

Oral SurgeryDentistry
8
논문|인용수 13·2021
Immediate loading protocols increase the risk of failure of implants placed by fully guided surgery in partially edentulous jaws: A randomized clinical trial
Kyung‐A Ko, Young Woo Song, Ji‐Man Park, Young‐Bum Park, Chang‐Sung Kim, Jung‐Seok Lee
SJR Q1Clinical Implant Dentistry and Related ResearchOA

AIM: To compare the 1-year outcomes of immediate loading (IL) and delayed loading (DL) protocols for implants placed by fully guided surgery in partially edentulous jaws. MATERIALS AND METHODS: This study included 72 patients who received implant surgery with either IL (93 implants, 36 patients) or DL (94 implants, 26 patients). A prefabricated provisional prosthesis was delivered immediately for the IL group (86 implants, 32 patients) with the exception of 4 subjects in whom an initial torque o

Oral SurgeryDentistry
9
논문|인용수 12·2019
Randomized controlled clinical trial on calcium phosphate coated and conventional SLA surface implants: 1‐year study on survival rate and marginal bone level
Kyung‐A Ko, Seungmin Kim, Seong‐Ho Choi, Jung‐Seok Lee
SJR Q1Clinical Implant Dentistry and Related ResearchOA

BACKGROUND: Calcium phosphate (CaP)-coated surface showed enhanced contact osteogenesis around dental implant and finally accelerate osseointegration in early healing phase. PURPOSE: The aim of this randomized controlled trial was to compare the peri-implant marginal bone level around uncoated and CaP-coated sandblasted, large-grit, acid-etched (SLA) surface implants during the first year after placement. MATERIALS AND METHODS: This study was performed upon 34 patients with randomized and double

Oral SurgeryDentistry
10
논문|인용수 12·2022
The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study
Kyung‐A Ko, Jin‐Young Park, Jung‐Seok Lee, Byoung Seok Ye, Ui‐Won Jung, Seong‐Ho Choi, Jae‐Kook Cha
SJR Q2Yonsei Medical JournalOA

There might be a causative relationship between the neglected missing dentition and the onset of dementia.

Speech and HearingHealth Professions
11
논문|인용수 12·2024
Risk of post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants: a cohort study using the common data model
Jooyeon Lee, Seunghyun Park, Da-Mi Kim, Kyung‐A Ko, Jin‐Young Park, Jung‐Seok Lee, Ui‐Won Jung, Jae‐Kook Cha
SJR Q1Scientific ReportsOA

This retrospective study aimed to determine risk factors associated with post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants. Patients taking anticoagulants who were planned to undergo periodontal flap operation, tooth extraction or implant surgery were included. Patients were divided into two subgroups according to the maintenance of anticoagulants following medical consultation: (1) maintenance group and (2) discontinuation group. The analysed patient-related

Cardiology and Cardiovascular MedicineMedicine
12
논문|인용수 9·2025
Patient‐Centred Preferences for Autonomy and Information‐Seeking Among Periodontal Patients in Dental Decision Making
Ji‐Young Jung, Kyung‐A Ko, Franz Josef Strauß, Jae‐Hong Lee, Jae‐Hong Lee, Junhewk Kim, Jung‐Seok Lee, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

BACKGROUND AND AIM: Managing periodontal disease often involves complex decisions involving multiple treatment options, and patient autonomy significantly influences this decision-making process. This study aimed to characterise the autonomy and information-seeking preferences among patients diagnosed with stage III/IV periodontitis, and to identify the factors influencing these preferences. MATERIALS AND METHODS: The survey included 96 patients diagnosed with periodontal disease, all of whom un

General Health ProfessionsHealth Professions
13
논문|인용수 5·2025
Particulate Versus Cross‐Linked Collagenated Bone Substitutes for Guided Bone Regeneration: A Randomized Controlled Trial
Ji‐Young Jung, Seung‐Hyun Park, K. Kim, Kyung‐A Ko, Dong‐Woon Lee, Jung‐Seok Lee
SJR Q1Clinical Oral Implants ResearchOA

AIM: To compare the dimensional outcomes of horizontal augmentation with the retentive-flap technique using particulate and cross-linked collagenated bone substitutes. MATERIALS AND METHODS: This two-centre, two-arm randomized clinical trial investigated 69 subjects: 34 in the particulate group and 35 in the collagenated group. Patients were randomly assigned to receive single implant placement with simultaneous guided bone regeneration (GBR) using either particulate deproteinized porcine bone m

Oral SurgeryDentistry
14
논문|인용수 4·1969
Treatment of femoral neck fractures
W Kawaji, Kyung‐A Ko
SJR Q1Injury
SurgeryMedicine
15
논문|인용수 3·2025
Association between dental care and improvement in long‐term care dependency levels in Korean beneficiaries
Bo‐Ah Lee, Jung Kyu Choi, Kyung‐A Ko, Jung‐Seok Lee, Young‐Taek Kim
SJR Q2Geriatrics and gerontology international/Geriatrics & gerontology international

Aim Although it has been reported that poor oral health is associated with worsening general health, oral health has been given less importance than general health in Long‐Term Care (LTC) insurance beneficiaries. The aim of this study was to evaluate the association between dental care and improvement in dependency levels of LTC insurance beneficiaries. Methods This study collected data from 53 130 beneficiaries who were newly approved for LTC in Korea in 2015. They were assigned to five LTC lev

PeriodonticsDentistry

대표 연구 분야

Oral SurgeryUrologyPeriodonticsCardiology and Cardiovascular MedicineGeneral Health ProfessionsNeurology

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