이현정 교수

High Resolution Image Download MS PowerPoint Slide Direct conversion of carbon dioxide (CO 2 ) to value-added chemicals by engineering of cyanobacteria has received attention as a sustainable strategy in food and chemical industries. Herein, Synechococcus elongatus PCC 7942, a model cyanobacterium, was engineered to produce α-farnesene from CO 2 . As a result of the lack of farnesene synthase (FS) activity in the wild-type cyanobacterium, we metabolically engineered S. elongatus PCC 7942 to expr

The eradication rate for the concomitant therapy was much higher than those of the standard triple therapy or sequential therapy (ClinicalTrials.gov number NCT01922765).

High Resolution Image Download MS PowerPoint Slide Metabolic engineering of cyanobacteria has received attention as a sustainable strategy to convert carbon dioxide to fatty acid-derived chemicals that are widely used in the food and chemical industries. Herein, Synechococcus elongatus PCC 7942, a model cyanobacterium, was engineered for the first time to produce fatty acid ethyl esters (FAEEs) from CO 2 . Due to the lack of an endogenous ethanol production pathway and wax ester synthase (AftA)

Holstein is known to provide higher milk yields than most other cattle breeds, and the dominant position of Holstein today is the result of various selection pressures. Holstein cattle have undergone intensive selection for milk production in recent decades, which has left genome-wide footprints of domestication. To further characterize the bovine genome, we performed whole-genome resequencing analysis of 10 Holstein and 11 Hanwoo cattle to identify regions containing genes as outliers in Holste

This study demonstrated the potential effects of the rumen microbiota on the deposition of intramuscular fat, known as marbling. Previous studies on fatty acid metabolism in beef cattle have mostly focused on biohydrogenating rumen bacteria, whereas those on the overall rumen microbiota—to understand their roles in marbling—have not been systematically performed. The rumen microbiota of 14 Korean beef cattle (Hanwoo), which showed similar carcass characteristics and blood metabolites but differe

Summary Designing synthetic pathways for efficient CO 2 fixation and conversion is essential for sustainable chemical production. Here we have designed a synthetic acetate‐acetyl‐CoA/malonyl‐CoA (AAM) bypass to overcome an enzymatic activity of pyruvate dehydrogenase complex. This synthetic pathway utilizes acetate assimilation and carbon rearrangements using a methyl malonyl‐CoA carboxyltransferase. We demonstrated direct conversion of CO 2 into acetyl‐CoA‐derived acetone as an example in photo

Biocontainment systems have been developed to mitigate the concerns regarding biosafety and environmental risk because of the possible escape of genetically modified organisms into the environment following large-scale outdoor cultivation. Here, we present a biocontainment system entailing genetically modified <i>Synechococcus elongatus</i> PCC 7942, also engineered for α-farnesene production using a de-evolutionary strategy. In this approach, the gene cluster encoding the β-carboxysome and the

Differences in the compositions of volatiles from dried omija fruits (Schisandra chinensis Baillon) cultivated in different areas (Mungyeong, Jangsu, Jechon, and Hoengseong) in South Korea were determined by applying principal component analysis to gas chromatography-mass spectrometry data sets. Quantitative assessments revealed that terpene hydrocarbons, such as germacrene D, β-selinene, α-ylangene, β-elemene, α-selinene, and (E)-β-farnesene, were the main volatiles in all omija fruit samples.

The use of ESD should be carefully considered for papillary adenocarcinoma-type EGC with suspected ESD indication after pre-treatment work-up because of the higher frequency of LN metastasis and additional surgeries.

The interrelationship between muscle and adipose tissues plays a major role in determining the quality of carcass traits. The objective of this study was to compare metabolic differences between muscle and intramuscular adipose (IMA) tissues in the longissimus dorsi (LD) of Hanwoo (Bos taurus coreanae) using the RNA-seq technology and a systems biology approach. The LD sections between the 6th and 7th ribs were removed from nine (each of three cows, steers, and bulls) Hanwoo beef cattle (carcass

Background: Mild cognitive impairment (MCI) is a condition with diverse causes and clinical outcomes that can be categorized into subtypes. [ 18 F]THK5351 has been known to detect reactive astrogliosis as well as tau which is accompanied by neurodegenerative changes. Here, we identified heterogeneous groups of MCI patients using THK retention patterns and a graph theory approach, allowing for the comparison of risk of progression to dementia in these MCI subgroups. Methods: Ninety-seven particip

본 연구의 목적은 월세로 거주하는 청년층 1인 가구를 4가지 지역(수도권 내 서울과 경인, 비수도권 내 특·광역시와 비특·광역시)으로 나뉘어 사회경제적 특성과 주거실태를 비교하고 주거비와 주거환경 평가의 결정변인을 분석한다. 2020년도 주거실태조사에서 추출한 총 2,110 가구를 통계 분석한 결과, 청년층 1인 가구는 수도권보다 비수도권 지역에 1.6배 더 많이 거주하였고, 모든 지역에서 대졸 이상의 고학력 30세의 남성 임금근로자였으며 슈바베 지수로 빈곤층이었다. 보증금과 임대료가 가장높은 서울 가구의 소득대비주거비가 가장 높은 동시에 주택유형, 주택규모, 주택연수 등 물리적 주거 조건이 가장 열악한 주거빈곤층인 반면 동일 생활권의 서울보다 주거 관련 비용이 상대적으로 저렴한 경인 지역 가구는 높은 소득으로 주거비 비율이가장 낮았으며 이는 근로활동 참여율과 소득이 비교적 낮아 주거빈곤층인 비수도권 가구보다 더 낮았다. 또한 조사대상 가구대다수는 원룸형 구조의 단독주택이나 비주택

Abstract Summary: We have synthesized three kinds of titanylphthalocyanines with different crystal structures (TiOPcs; PcT2000R, PcT3000R, and PcT1100S) and analyzed their crystal structure by X‐ray Diffraction (XRD), Fourier transfer IR (FT‐IR) spectroscopy, and Transmission Electron Microscope (TEM). From experimental results, we have confirmed that PcT2000R was estimated to be alpha‐form; PcT3000R was beta‐form, and PcT1100S was gamma‐form. Quasi‐solid state dye‐sensitized solar cell (DSSC) d