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김이준 교수

Lee-Joon Kim

이화여자대학교 의학과 · 의학

연구실 소개

김이준 교수의 연구실은 주로 암의 생존율, 치료 전략 및 예후 요인을 다각도로 분석하는 데 초점을 맞추고 있습니다. 특히 투명한 생존 분석을 위해 대규모 인구 기반 데이터베이스(예: SEER)를 활용한 전인적 연구를 수행하며, 수술, 방사선 치료, 화학요법 등의 치료 전략이 암 환자에게 미치는 영향을 정량적으로 평가합니다. 또한, 기계학습 기반의 예측 모델 개발을 통해 비정상적 수술 후 30일 사망 위험도 정확하게 예측하고자 하며, 임상적 의사결정 지원에 기여하고자 합니다.

암 생존율치료 전략 평가대규모 데이터 분석기계학습 예측 모델예후 요인 분석

연구 현황

논문 수
85
총 인용 수
951
최근 5년 논문
42
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
42총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
205총합
20222023202420252026

주요 논문

15
1
논문|인용수 106·2018
Molecular subtype predicts incidence and prognosis of brain metastasis from breast cancer in SEER database
Yi‐Jun Kim, Kim Js, In Ah Kim
SJR Q1Journal of Cancer Research and Clinical OncologyOA
Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 88·2020
Increasing incidence and improving survival of oral tongue squamous cell carcinoma
Yi‐Jun Kim, Jin Ho Kim
SJR Q1Scientific ReportsOA

We evaluated changes in incidence, relative survival (RS), and conditional survival (CS) of head and neck squamous cell carcinoma (HNSCC), focusing on oral tongue squamous cell carcinoma (OTSCC). Data of 74 680 HNSCC patients from 1976 to 2015 were obtained from the Surveillance, Epidemiology, and End Results database. Five anatomical sites and their subsites were analyzed. Annual percent change (APC) of incidence was calculated. RS and CS were compared across the four decades. Adjusted hazard r

OtorhinolaryngologyMedicine
3
논문|인용수 79·2016
Radiation therapy for malignant phyllodes tumor of the breast: An analysis of SEER data
Yi‐Jun Kim, Kyubo Kim
SJR Q1The BreastOA

PURPOSE: Malignant phyllodes tumor of the breast (MPTB) accounts for less than 1% of whole breast neoplasm. Surgery is regarded as the primary treatment of choice in patients with MPTB, but the necessity of postoperative radiation therapy (RT) has been a subject of debate. Our aim was to evaluate effects of postoperative RT for MPTB using a large population database. METHODS: Using the Surveillance, Epidemiology, and End Results Program (SEER) database (1983-2013), clinico-pathologic prognostic

Pathology and Forensic MedicineMedicine
4
논문|인용수 51·2022
Multi-center validation of machine learning model for preoperative prediction of postoperative mortality
Seung Wook Lee, Hyung‐Chul Lee, Jungyo Suh, Kyung Hyun Lee, Heonyi Lee, Suryang Seo, Tae Kyong Kim, Sang-wook Lee, Yi‐Jun Kim
SJR Q1npj Digital MedicineOA

Accurate prediction of postoperative mortality is important for not only successful postoperative patient care but also for information-based shared decision-making with patients and efficient allocation of medical resources. This study aimed to create a machine-learning prediction model for 30-day mortality after a non-cardiac surgery that adapts to the manageable amount of clinical information as input features and is validated against multi-centered rather than single-centered data. Data were

Cardiology and Cardiovascular MedicineMedicine
5
논문|인용수 33·2018
Surgery vs. radiotherapy for locally advanced hypopharyngeal cancer in the contemporary era: A population‐based study
Yi‐Jun Kim, Rena Lee
SJR Q1Cancer MedicineOA

OBJECTIVES: To compare overall survival (OS) in locally advanced hypopharyngeal cancer treated with surgery or definitive chemoradiotherapy in the contemporary era. METHODS: From 2010 to 2015, data for patients diagnosed with hypopharyngeal cancer (T2-T4aM0) and treated with total pharyngectomy with lymph node dissection (surgery group) or definitive radiotherapy and chemotherapy (chemoradiotherapy group) was retrieved from the SEER database. Multivariate analyses were performed in each subgroup

OtorhinolaryngologyMedicine
6
논문|인용수 26·2015
Prognostic analysis of uterine cervical cancer treated with postoperative radiotherapy: importance of positive or close parametrial resection margin
Yi‐Jun Kim, Kyung-Ja Lee, Kyung Ran Park, Jiyoung Kim, Wonguen Jung, Rena Lee, Seung Cheol Kim, Hye Sung Moon, Woong Ju, Yun Hwan Kim, Jihae Lee
SJR Q2Radiation Oncology JournalOA

PURPOSE: To analyze prognostic factors for locoregional recurrence (LRR), distant metastasis (DM), and overall survival (OS) in cervical cancer patients who underwent radical hysterectomy followed by postoperative radiotherapy (PORT) in a single institute. MATERIALS AND METHODS: Clinicopathologic data of 135 patients with clinical stage IA2 to IIA2 cervical cancer treated with PORT from 2001 to 2012 were reviewed, retrospectively. Postoperative parametrial resection margin (PRM) and vaginal rese

Obstetrics and GynecologyMedicine
7
논문|인용수 23·2019
Survival benefit of radiotherapy after surgery in de novo stage IV breast cancer: a population-based propensity-score matched analysis
Yi‐Jun Kim, So‐Youn Jung, Kyubo Kim
SJR Q1Scientific ReportsOA

The survival benefit from radiotherapy in stage IV breast cancer has not been fully evaluated. We investigated the survival benefit of radiotherapy after surgery in de novo stage IV breast cancer. Using a population-based database (the Surveillance, Epidemiology, and End Results database 18, 2010-2013), patients diagnosed with de novo stage IV breast cancer were divided into those undergoing surgery alone (no-radiotherapy group) and those undergoing surgery followed by radiotherapy (radiotherapy

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
논문|인용수 20·2019
The Feasibility of Spinal Stereotactic Radiosurgery for Spinal Metastasis with Epidural Cord Compression
Yi‐Jun Kim, Jin Ho Kim, Kyubo Kim, Hak Jae Kim, Eui Kyu Chie, Kyung Hwan Shin, Hong-Gyun Wu, Il Han Kim
SJR Q1Cancer Research and TreatmentOA

Spinal SRS for spinal metastasis with Bilsky grade 2 ESCC did not increase the LP rate, was not associated with severe neurotoxicity, and showed moderate VCF and pain response rates. Bilsky grade 3 had a high LP rate.

SurgeryMedicine
9
논문|인용수 16·2019
Optimal extent of resection for glioblastoma according to site, extension, and size: a population-based study in the temozolomide era
Yi‐Jun Kim, David J. Lee, Chul‐Kee Park, In Ah Kim
SJR Q1Neurosurgical Review
GeneticsMedicine
10
논문|인용수 16·2023
COVID-19, maternal, and neonatal outcomes: National Mother-Child Cohort (NMCC) of K-COV-N cohort in South Korea
Jongmin Oh, Whanhee Lee, Choong-jong Kim, Yi‐Jun Kim, Hyesook Park, Ji Hyen Lee, Mi Hye Park, Seulbi Lee, Eun‐Hee Ha, Kyung A. Lee
SJR Q1PLoS ONEOA

Throughout the COVID-19 pandemic, pregnant women have been classified as a vulnerable population. However, the evidence on the effect of infection during pregnancy on maternal and neonatal outcomes is still uncertain, and related research comprising a large population of pregnant women in Asian countries is limited. We constructed a national cohort including mothers and children (369,887 pairs) registered in the Prevention Agency-COVID-19-National Health Insurance Service (COV-N), from January 1

Obstetrics and GynecologyMedicine
11
논문|인용수 14·2017
Lymph node ratio determines the benefit of adjuvant radiotherapy in pathologically 3 or less lymph node-positive prostate cancer after radical prostatectomy: a population-based analysis with propensity-score matching
Yi‐Jun Kim, Changhoon Song, Keun‐Yong Eom, In Ah Kim, Kim Js
SJR Q2OncotargetOA

ART after RP showed a CSS benefit in prostate adenocarcinoma with 4 or more involved LNs irrespective of LNR. In prostate adenocarcinoma with up to 3 involved LNs after RP, ART may provide CSS benefits when the LNR is 7% or higher. The number of LN dissections required to achieve an LNR below 7% is 15, 29, and 43 or more for 1, 2, and 3 involved LNs, respectively.

Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 12·2017
Conditional survival in patients with gallbladder cancer
Yi‐Jun Kim, Kyubo Kim
Chinese Journal of CancerOA

BACKGROUND: Conditional survival (CS) has been established as a clinically relevant prognostic factor for cancer survivors, and the CS in gallbladder (GB) cancer has not yet been fully evaluated. In this study, we evaluated the cancer-specific CS rate and cancer-specific survival (CSS) rate in patients with GB cancer at multiple time points and investigated prognostic factors which affect cancer-specific CS rate to provide more accurate survival information. METHODS: Between 2004 and 2013, a tot

SurgeryMedicine
13
논문|인용수 11·2016
Two-year Follow-up of Volumetric-modulated Arc Therapy for Treating Internal Mammary Nodes in Locally Advanced Breast Cancer
Yi‐Jun Kim, Kyubo Kim, Rena Lee, Jiyoung Kim, Wonguen Jung, Nam Sun Paik, Byung-In Moon, Woosung Lim, Jihae Lee
SJR Q2Anticancer ResearchOA

BACKGROUND/AIM: We evaluated dosimetric and clinical results of volumetric-modulated arc therapy (VMAT) treating internal mammary nodes (IMNs) in patients with locally advanced breast cancer. PATIENTS AND METHODS: Between July 2012 and December 2013, treatment outcomes of 31 patients with stage III breast cancer treated with postoperative radiotherapy including the IMN field using VMAT were analyzed. RESULTS: The median follow-up was 25.2 months. VMAT showed good homogeneity and improved conform

Cancer ResearchBiochemistry, Genetics and Molecular Biology
14
논문|인용수 10·2017
Change in carbohydrate antigen 19-9 level as a prognostic marker of overall survival in locally advanced pancreatic cancer treated with concurrent chemoradiotherapy
Yi‐Jun Kim, Hyeon Kang Koh, Eui Kyu Chie, Do‐Youn Oh, Yung‐Jue Bang, Eun Mi Nam, Kyubo Kim
SJR Q1International Journal of Clinical Oncology
OncologyMedicine
15
논문|인용수 10·2021
Mortality Risk within 14 Days after Coronavirus Disease 2019 Diagnosis in Dementia Patients: A Nationwide Analysis
Yi‐Jun Kim, Yongho Jee, Sholhui Park, Eun‐Hee Ha, Inho Jo, Hyang Woon Lee, Myung Seon Song
SJR Q2Dementia and Geriatric Cognitive DisordersOA

INTRODUCTION: The study evaluated the increased mortality risk within 14 days of coronavirus disease 2019 (COVID-19) diagnosis in dementia patients. METHODS: This retrospective study was conducted from February to April 2020 using the COVID-19 patients' database from the Korea Disease Control and Prevention Agency. The risk factors for early death within 14 days were determined using generalized logistic regression performed in a stepwise manner. Dementia patients diagnosed with COVID-19 were us

NeurologyMedicine

대표 연구 분야

Health, Toxicology and MutagenesisCancer ResearchObstetrics and GynecologyInfectious DiseasesPulmonary and Respiratory MedicineSurgery

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