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선우준 교수

Leonard Sunwoo

서울대학교 영상의학과 · 의학

연구실 소개

선우준 교수의 연구실은 의료 영상 분야에서 신호 복원과 진단 정밀도 향상을 목표로 하며, 주로 자기공명영상(MRI)의 고속 촬영 기술과 병변 진단에 기반한 딥러닝 기반 알고리즘 개발에 집중하고 있습니다. 특히 k-공간 영역에서의 저질서 행렬 복원 기법과 데이터 기반 프레임렛 기반 신경망 설계를 통해 촬영 시간 단축과 동시에 높은 해상도 복원을 실현하고자 합니다. 또한 망막 사진과 뇌 영상에서의 나이 및 성별 예측 모델을 통해 노화와 혈관성 질환의 영상적 특징을 분석하는 연구도 진행 중입니다.

k-공간 복원딥러닝의료 영상MRI 가속화병변 진단

연구 현황

논문 수
115
총 인용 수
1,904
최근 5년 논문
65
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
65총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
336총합
20222023202420252026

주요 논문

15
1
논문|인용수 336·2019
k -Space Deep Learning for Accelerated MRI
Yoseob Han, Leonard Sunwoo, Jong Chul Ye
SJR Q1IEEE Transactions on Medical Imaging

The annihilating filter-based low-rank Hankel matrix approach (ALOHA) is one of the state-of-the-art compressed sensing approaches that directly interpolates the missing k -space data using low-rank Hankel matrix completion. The success of ALOHA is due to the concise signal representation in the k -space domain, thanks to the duality between structured low-rankness in the k -space domain and the image domain sparsity. Inspired by the recent mathematical discovery that links convolutional neural

Computational MechanicsEngineering
2
리뷰|인용수 119·2020
Brain metastasis detection using machine learning: a systematic review and meta-analysis
Se Jin Cho, Leonard Sunwoo, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Jae Hyoung Kim
SJR Q1Neuro-OncologyOA

BACKGROUND: Accurate detection of brain metastasis (BM) is important for cancer patients. We aimed to systematically review the performance and quality of machine-learning-based BM detection on MRI in the relevant literature. METHODS: A systematic literature search was performed for relevant studies reported before April 27, 2020. We assessed the quality of the studies using modified tailored questionnaires of the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) criteria and the Ch

Pulmonary and Respiratory MedicineMedicine
3
논문|인용수 108·2018
Deep Learning in Diagnosis of Maxillary Sinusitis Using Conventional Radiography
Youngjune Kim, Kyong Joon Lee, Leonard Sunwoo, Dongjun Choi, Chang-Mo Nam, Jungheum Cho, Jihyun Kim, Yun Jung Bae, Roh‐Eul Yoo, Byung Se Choi, Cheolkyu Jung, Jae Hyoung Kim
SJR Q1Investigative Radiology

OBJECTIVES: The aim of this study was to compare the diagnostic performance of a deep learning algorithm with that of radiologists in diagnosing maxillary sinusitis on Waters' view radiographs. MATERIALS AND METHODS: Among 80,475 Waters' view radiographs, examined between May 2003 and February 2017, 9000 randomly selected cases were classified as normal or maxillary sinusitis based on radiographic findings and divided into training (n = 8000) and validation (n = 1000) sets to develop a deep lear

OtorhinolaryngologyMedicine
4
논문|인용수 84·2020
Unpaired Deep Learning for Accelerated MRI Using Optimal Transport Driven CycleGAN
Gyutaek Oh, Byeongsu Sim, Hyungjin Chung, Leonard Sunwoo, Jong Chul Ye
SJR Q1IEEE Transactions on Computational Imaging

Recently, deep learning approaches for accelerated MRI have been extensively studied thanks to their high performance reconstruction in spite of significantly reduced run-time complexity. These neural networks are usually trained in a supervised manner, so matched pairs of subsampled, and fully sampled k-space data are required. Unfortunately, it is often difficult to acquire matched fully sampled k-space data, since the acquisition of fully sampled k-space data requires long scan time, and ofte

Radiology, Nuclear Medicine and ImagingMedicine
5
논문|인용수 79·2020
Effects of Hypertension, Diabetes, and Smoking on Age and Sex Prediction from Retinal Fundus Images
Yong Dae Kim, Kyoung Jin Noh, Seong Jun Byun, Soochahn Lee, Tackeun Kim, Leonard Sunwoo, Kyong Joon Lee, Si‐Hyuck Kang, Kyu Hyung Park, Sang Jun Park
SJR Q1Scientific ReportsOA

Abstract Retinal fundus images are used to detect organ damage from vascular diseases (e.g. diabetes mellitus and hypertension) and screen ocular diseases. We aimed to assess convolutional neural network (CNN) models that predict age and sex from retinal fundus images in normal participants and in participants with underlying systemic vascular-altered status. In addition, we also tried to investigate clues regarding differences between normal ageing and vascular pathologic changes using the CNN

Radiology, Nuclear Medicine and ImagingMedicine
6
논문|인용수 65·2016
Differentiation of Glioblastoma from Brain Metastasis: Qualitative and Quantitative Analysis Using Arterial Spin Labeling MR Imaging
Leonard Sunwoo, Tae Jin Yun, Sung‐Hye You, Roh‐Eul Yoo, Koung Mi Kang, Seung Hong Choi, Ji‐hoon Kim, Chul‐Ho Sohn, Sun‐Won Park, Cheolkyu Jung, Chul‐Kee Park
SJR Q1PLoS ONEOA

ASL perfusion MR imaging can aid in the differentiation of GBM from brain metastasis.

GeneticsMedicine
7
논문|인용수 60·2019
Fully Automatic Segmentation of Acute Ischemic Lesions on Diffusion-Weighted Imaging Using Convolutional Neural Networks: Comparison with Conventional Algorithms
Ilsang Woo, A-Reum Lee, Seung Chai Jung, Hyunna Lee, Namkug Kim, Se Jin Cho, Donghyun Kim, Jung Bin Lee, Leonard Sunwoo, Dong‐Wha Kang
SJR Q1Korean Journal of RadiologyOA

The CNN algorithm for automatic segmentation of acute ischemic lesions on DWI achieved Dice indices greater than or equal to 0.85 and showed superior performance to conventional algorithms.

EpidemiologyMedicine
8
논문|인용수 56·2017
Computer-aided detection of brain metastasis on 3D MR imaging: Observer performance study
Leonard Sunwoo, Young Jae Kim, Seung Hong Choi, Kwang Gi Kim, Ji Hee Kang, Yeonah Kang, Yun‐Jung Bae, Roh‐Eul Yoo, Jihang Kim, Kyong Joon Lee, Seung-Hyun Lee, Byung Se Choi
SJR Q1PLoS ONEOA

CAD as a second reader helps radiologists improve their diagnostic performance in the detection of BM on MR imaging, particularly for less-experienced reviewers.

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 51·2012
Correlation of apparent diffusion coefficient values measured by diffusion MRI and MGMT promoter methylation semiquantitatively analyzed with MS‐MLPA in patients with glioblastoma multiforme
Leonard Sunwoo, Seung Hong Choi, Chul‐Kee Park, Jin Wook Kim, Kyung Sik Yi, Woong Jae Lee, Tae Jin Yoon, Sang Woo Song, Ja‐Eun Kim, Ji Young Kim, Tae Min Kim, Se‐Hoon Lee
SJR Q1Journal of Magnetic Resonance ImagingOA

PURPOSE: To retrospectively determine whether the apparent diffusion coefficient (ADC) values correlate with O(6)-methylguanine DNA methyltransferase (MGMT) promoter methylation semiquantitatively analyzed by methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) in patients with glioblastoma. MATERIALS AND METHODS: The study was approved by the Institutional Review Board and was Health Insurance Portability and Accountability Act (HIPAA) compliant. Newly diagnosed patie

GeneticsMedicine
10
논문|인용수 51·2018
Machine learning for detecting moyamoya disease in plain skull radiography using a convolutional neural network
Tackeun Kim, Jaehyuk Heo, Dong‐Kyu Jang, Leonard Sunwoo, Joonghee Kim, Kyong Joon Lee, Si‐Hyuck Kang, Sang Jun Park, O-Ki Kwon, Chang Wan Oh
SJR Q1EBioMedicineOA

DL can distinguish MMD cases within specific ages from controls in plain skull radiograph images with considerable accuracy and AUROC. The viscerocranium may play a role in MMD-related skull features. FUND: This work was supported by grant no. 18-2018-029 from the Seoul National University Bundang Hospital Research Fund.

RheumatologyMedicine
11
논문|인용수 43·2021
Deep Learning for Diagnosis of Paranasal Sinusitis Using Multi-View Radiographs
Yejin Jeon, Kyeorye Lee, Leonard Sunwoo, Dongjun Choi, Dong Yul Oh, Kyong Joon Lee, Youngjune Kim, Jeong‐Whun Kim, Se Jin Cho, Sung Hyun Baik, Roh‐Eul Yoo, Yun Jung Bae
SJR Q2DiagnosticsOA

Accurate image interpretation of Waters’ and Caldwell view radiographs used for sinusitis screening is challenging. Therefore, we developed a deep learning algorithm for diagnosing frontal, ethmoid, and maxillary sinusitis on both Waters’ and Caldwell views. The datasets were selected for the training and validation set (n = 1403, sinusitis% = 34.3%) and the test set (n = 132, sinusitis% = 29.5%) by temporal separation. The algorithm can simultaneously detect and classify each paranasal sinus us

OtorhinolaryngologyMedicine
12
논문|인용수 27·2021
Deep Learning-Based Computer-Aided Detection System for Automated Treatment Response Assessment of Brain Metastases on 3D MRI
Jungheum Cho, Young Jae Kim, Leonard Sunwoo, Gi Pyo Lee, Toan Nguyen, Se Jin Cho, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Cheolkyu Jung, Chul‐Ho Sohn, Jungho Han
SJR Q2Frontiers in OncologyOA

BACKGROUND: Although accurate treatment response assessment for brain metastases (BMs) is crucial, it is highly labor intensive. This retrospective study aimed to develop a computer-aided detection (CAD) system for automated BM detection and treatment response evaluation using deep learning. METHODS: We included 214 consecutive MRI examinations of 147 patients with BM obtained between January 2015 and August 2016. These were divided into the training (174 MR images from 127 patients) and test da

Pulmonary and Respiratory MedicineMedicine
13
리뷰|인용수 27·2021
Classification of true progression after radiotherapy of brain metastasis on MRI using artificial intelligence: a systematic review and meta-analysis
Hae Young Kim, Se Jin Cho, Leonard Sunwoo, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Cheolkyu Jung, Jae Hyoung Kim
SJR Q1Neuro-Oncology AdvancesOA

BACKGROUND: Classification of true progression from nonprogression (eg, radiation-necrosis) after stereotactic radiotherapy/radiosurgery of brain metastasis is known to be a challenging diagnostic task on conventional magnetic resonance imaging (MRI). The scope and status of research using artificial intelligence (AI) on classifying true progression are yet unknown. METHODS: We performed a systematic literature search of MEDLINE and EMBASE databases to identify studies that investigated the perf

Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 25·2015
Evaluation of the degree of arteriovenous shunting in intracranial arteriovenous malformations using pseudo-continuous arterial spin labeling magnetic resonance imaging
Leonard Sunwoo, Chul‐Ho Sohn, Jong Young Lee, Kyung Sik Yi, Tae Jin Yun, Seung Hong Choi, Young Dae Cho, Ji‐hoon Kim, Sun‐Won Park, Moon Hee Han, Sun Ha Paek, Yong Hwy Kim
SJR Q1Neuroradiology
NeurologyMedicine
15
논문|인용수 16·2024
Prediction of treatment response after stereotactic radiosurgery of brain metastasis using deep learning and radiomics on longitudinal MRI data
Se Jin Cho, Wonwoo Cho, Dongmin Choi, Gyuhyeon Sim, So Yeong Jeong, Sung Hyun Baik, Yun Jung Bae, Byung Se Choi, Jae Hyoung Kim, Sooyoung Yoo, Jung Ho Han, Chae‐Yong Kim
SJR Q1Scientific ReportsOA

We developed artificial intelligence models to predict the brain metastasis (BM) treatment response after stereotactic radiosurgery (SRS) using longitudinal magnetic resonance imaging (MRI) data and evaluated prediction accuracy changes according to the number of sequential MRI scans. We included four sequential MRI scans for 194 patients with BM and 369 target lesions for the Developmental dataset. The data were randomly split (8:2 ratio) for training and testing. For external validation, 172 M

Pulmonary and Respiratory MedicineMedicine

대표 연구 분야

EpidemiologyRadiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineNeurologyOtorhinolaryngologyBiomedical Engineering

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