정미애 교수
Mi Ae Jeong
한양대학교 마취통증의학과 · 의학
연구실 소개
정미애 교수의 연구실은 신경손상 회복과 재생의 기전을 밝히고, 이를 위한 비약리학적 치료 전략을 개발하는 데 초점을 맞추고 있습니다. 특히 체중 감량을 유도하는 식이제한(예: 번갈아가며 식사하는 방식)이 척수손상 후 신경기능 회복에 미치는 영향을 실험적으로 규명하며, 신경가소성 향상과 기능적 회복을 유도하는 메커니즘을 탐구하고 있습니다. 또한 3차원 프린팅 기반의 생체적합성 구조물 개발을 통해 조직 재생을 위한 맞춤형 생체공학 솔루션도 함께 연구하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Spinal cord injury (SCI) often results in a loss of motor and sensory function. Currently there are no validated effective clinical treatments. Previously we found in rats that dietary restriction, in the form of every-other-day fasting (EODF), started prior to (pre-EODF), or after (post-EODF) an incomplete cervical SCI was neuroprotective, increased plasticity, and promoted motor recovery. Here we examined if EODF initiated prior to, or after, a T10 thoracic contusion injury would similarly lea
Compared to nerve stimulation or classic paraesthesia techniques, ultrasound (US)-guided popliteal sciatic nerve block requires a smaller volume of local anaesthetic. The up-and-down method was used to determine the minimum effective anaesthetic volume of 0.5% ropivacaine necessary for US-guided popliteal sciatic nerve block to achieve successful surgical anaesthesia for foot and ankle surgery. The study included 32 patients receiving an US-guided popliteal sciatic nerve bock. The starting dose
Three-dimensional (3D) printing, combined with medical imaging technologies, such as computed tomography and magnetic resonance imaging (MRI), has shown a great potential in patient-specific tissue regeneration. Here, we successfully fabricated an ultrathin tubular free-form structure with a wall thickness of several tens of micrometers that is capable of providing sufficient mechanical flexibility. Such a thin geometry cannot easily be achieved by 3D printing alone; therefore, it was realized t
Scrub typhus, also called tsutsugamushi disease, is classified as a Group 3 disease in Korea according to the National Notifiable Diseases Surveillance Systems. It is an infectious disease transmitted to humans through the bite of mites that are infected with an intracellular parasite called Orientia tsutsugamushi (Family: Rickettsiaceae). This study aims to identify the demographic characteristics of the infected cases according to profession, region, gender, and onset period and provide a basi
Objective To determine whether intubation education using the Pentax Airway Scope (AWS) in normal airways is more useful than direct laryngoscopy (Macintosh laryngoscope) in novice personnel. Methods Eleven intern doctors without intubation experience performed 60 sequential intubations with each device on a manikin and 10 sequential intubations in adult patients. The time required for successful intubation, percentage of glottic opening (POGO) score, number of intubation attempts, and number of
OBJECTIVE: To investigate emergence times with different fresh gas flow rates, following desflurane anaesthesia. METHODS: Patients undergoing surgery with desflurane anaesthesia were randomly assigned to receive fresh gas flow rates of 100% oxygen during emergence of 2 l/min (group D2), 4 l/min (group D4) or 6 l/min (group D6). Time to eye opening, spontaneous movement and extubation (emergence time) were assessed after desflurane discontinuation. The end-tidal concentration of desflurane and bi
Erythropoietin and iron have individually shown beneficial effects on early-phase liver regeneration following partial hepatectomy (PHx); however, there are limited data on the combined effect on late-phase liver regeneration after PHx. Here we examined combined effects of recombinant human erythropoietin (rhEPO, 3,000 IU/kg) and iron isomaltoside (IIM, 40 mg/kg) on late-phase liver regeneration following PHx and investigated the possible underlying mechanism. Rats administrated with rhEPO showe
BACKGROUND: Laryngeal mask airway (LMA) has been increasingly used for airway management; however, LMA insertion can be difficult and cause adverse effects. Therefore, the rapid, safe, and effective insertion of LMA is necessary. This study aimed to compare the efficacy of the standard method with that of the 30° curved tongue depressor-aided technique for LMA insertion to determine the superior technique. METHODS: This study included 154 patients aged 18-70 years (American Society of Anesthesio
Editor, Supraglottic airway devices (SADs) have been widely used in general anaesthesia or in difficult tracheal intubation states, but sometimes incomplete insertion still occurs.1–4 Therefore, several methods5–9 have been introduced for easy and safe insertion of SADs as well as new devices.10 The authors would like to introduce an easier method to insert SADs using the tongue depressor used for operations in the mouth. The method is as follows. After induction of anaesthesia, press the patien
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