김미경 교수

Patients with VAIN are at high-risk of recurrence, but the risk of progression to vaginal cancer is relatively low. Laser or excision provides higher regression rate than topical agent or observation, and high-risk HPV positivity is a risk factor for recurrence. Whatever the treatment method is used, however, the high rate of recurrence warrants long-term follow-up surveillance.

본 연구는 한국청소년패널조사(KYPS)의 중2패널 3차년도와 4차년도 자료를 이용하여 청소년의 성적이 학업스트레스에 미치는 영향에서의 성별 차이를 분석하였다. 이를 위해 인문계 고1과 고2학생들을 대상으로 위계적 회귀분석을 실시한 결과, 청소년의 성적은 학업스트레스에 유의한 영향을 미쳤으며, 성적수준에 따라서 학업스트레스를 받는 정도가 다르게 나타났다. 고1의 경우는 성적이 낮은 집단이 학업스트레스가 높았으며, 고2의 경우에서는 성적이 중간인 집단의 학업스트레스가 성적이 상․하위인 집단이 받는 학업스트레스보다 더 높은 것으로 나타났다. 또한 성별에 따른 주요변수의 차이를 분석했을 때, 여자 청소년은 남자 청소년보다 학업스트레스, 불안․우울, 부모애착과 친구애착이 유의하게 높았으며, 남자 청소년은 여자 청소년에 비해 자아통제와 자기신뢰감이 높게 나타났다. 마지막으로 청소년의 성적과 학업스트레스의 관계에서 성별 조절효과는 학업스트레스가 높은 고2에서만 나타났다. 남녀 청소년 모두에게 성

OBJECTIVE: The aim of this study was to develop a nomogram for predicting the 5-year disease-free survival (DFS) after radical hysterectomy for early-stage cervical cancer. PATIENTS AND METHODS: An institutional database of 275 consecutive patients treated at Seoul National University Hospital for stage I to stage IIA cervical cancer was used to develop a nomogram based on Cox proportional hazards regression model. The developed nomogram was internally validated with bootstrapping, and performan

OBJECTIVE: To evaluate the histologic correlation and clinical significance of atypical glandular cells (AGC) detected on Pap tests. METHODS: Pap tests interpreted as AGC were retrieved from an institutional cytopathology database. The AGC subcategories according to the Bethesda system 2001 include atypical glandular cells, not otherwise specified (AGC-NOS), atypical endometrial cells (AEM), and atypical endocervical cells (AEC). Clinicopathologic variables were collected from medical records re

The current study supported previous studies suggesting that specific symptoms were useful in identifying women with ovarian cancer.

DNA methylation status, especially in the ADCYAP1 and PAX1 genes, showed relatively good specificity, ranging from 90% to 94%. The possible additive and complementary roles of DNA methylation testing with respect to conventional cervical cancer screening programs will need to be validated in prospective population-based studies.

Our findings of the associations between MMR deficiency and poor prognostic factors, such as LVSI and LN metastasis, may suggest the prognostic value of MMR status in EC and need further prospective validation studies.

Epithelial-mesenchymal transition (EMT) has been suggested to contribute to tumor progression and acquisition of therapeutic resistance. To assess the clinical significance of EMT-associated proteins, we evaluated the expression of Snail and Slug, the key regulators of EMT, in the primary ovarian cancer samples (n = 103) by immunohistochemistry. Snail was differentially expressed according to the histologic subtype (P = 0.001) and was predominantly expressed in serous and endometrioid types. In

Rising global food prices and the increasing prevalence of food insecurity highlight the imprudence of food waste and the inefficiencies of the current food system. Upcycling food by-products holds significant potential for mitigating food loss and waste within the food supply chain. Food by-products can be utilized to extract nanocellulose, a material that has obtained substantial attention recently due to its renewability, biocompatibility, bioavailability, and a multitude of remarkable proper