구민아 교수

Biomaterials for clinical applications such as medical and implant devices require evaluation to determine their biocompatibility. This study aimed to evaluate the initial biological safety of polyketone (PK) polymers, which have potential use as biomaterials. It presents results from cytotoxicity and genotoxicity assays and tests determining the levels of skin irritation, sensitization, and acute systemic toxicity caused by PK. The PK polymers showed no cytotoxicity, genotoxicity, allergenicity

Background: The initial procedure of the development of engineered tissues is cell seeding into three-dimensional polymer scaffolds. However, it is hard to make the cells invade into scaffold due to the characteristic of pore and material. Electrospun poly (L-lactic acid) scaffold and flow perfusion system were used to overcome these seeding problems. Materials and Methods: Before starting the experiment, we set up the parallel plate chamber system to observe endothelial cell migration under flo

Background: Cell migration is an essential activity of the cells in various biological phenomena. The evidence that electrotaxis plays important roles in many physiological phenomena is accumulating. In electrotaxis, cells move with a directional tendency toward the anode or cathode under direct-current electric fields. Indium tin oxide, commonly referred to as ITO has high luminous transmittance, high infrared reflectance, good electrical conductivity, excellent substrate adherence, hardness an

This study aims to examine the organ performing techniques for offering new interpretations of organ music and enlarging repertories of dance music. In order to the effective results this study adjusts J.S. Bach’s «French Suite No.5» to the modern organ. Based on each song’s characteristics in the suite, it suggests organ registration and articulations. As a result of the study, ‘basse danse’ such as allemande, sarabande usually used flute tones which can express slow movements and the weight an

Abstract With breast cancer incidence rising worldwide—including in younger Korean women in their 40s—there is an urgent need for advanced disease models that capture mechanobiological features unique to this population. Post-surgical hormonal alterations and the high prevalence of bone metastases further complicate outcomes, underscoring the need for strategies addressing both primary tumor biomechanics and skeletal microenvironments. To meet this need, we developed a three-dimensional (3D) bre

Background: Titanium is a well proven implantable material especially for osseointegratable implants by its biocompatibility and anti-corrosive surface properties. Surface characteristics of the implant play an important role for the evolution of bone tissue of the recipient site. Among the various surface modification methods, plasma treatment is one of the promising methods for enhance biocompatibility. We made microwave-induced argon plasma at atmospheric pressure to improve in titanium surfa

Cell migration is an essential activity of the cells in various biological phenomena such as embryonic development,wound healing of damaged tissue, capillary vascularization in angiogenesis and migration of leukocytes to kill the bacteria around the wound site. The properties of nanofibrous surface enhancing cell adhesion, proliferation, migration and differentiation are necessary for application in tissue engineering. Recently, fabricated scaffolds at the nanometer scale are very similar to the