김민재 교수

Background/Aims: We explored the mechanisms underlying the improvement of postoperative ileus (POI) following probiotic pretreatment. We assessed intestinal permeability, inflammation, tight junction (TJ) protein expression in the gut epithelium, and plasma interleukin (IL)-17 levels in a guinea pig model of POI. Methods: Guinea pigs were divided into control, POI, and probiotic groups. The POI and probiotic groups underwent surgery, but the probiotic group received probiotics before the procedu

The purpose of this study is to examine the sleep environment, sleep quality and to reveal the relationship between sleep environment and obstructive sleep apnea hypopnea syndrome. The subjects of this study are twenty four women who live in an apartment in Seoul. We conducted pre-sleep questionnaire and post-sleep questionnaire. We measured equivalent noise level, illumination, air temperature, relative humidity, MRT, CO2 concentration, and AHI of each subject in their bedrooms. In case of both

BACKGROUND: Helicobacter pylori infection is a significant contributing factor of gastric cancer. Metachronous neoplasms also pose a risk. The mechanism underlying the impact of H. pylori eradication on preventing metachronous gastric cancer is unclear. This study aimed to investigate immunity changes in gastric mucosa after H. pylori eradication and to identify mechanisms preventing metachronous recurrence. MATERIALS AND METHODS: Patients diagnosed with gastric neoplasm and H. pylori infection,

The purpose of this study was to evaluate the association between type of physical activity(PA), sedentary time(ST) and lower back pain(LBP). Additionally, the association between lifestyle, demographic factors and lower back pain was investigated. A total of 1,781 subjects above 50 years of age who had participated in the Korean National Health and Nutrition Examination Survey(KNHANES) of 2014 were included for the analysis in this study. Chi-square test and univariable logistic regression were

Purpose We investigated the clinicopathologic information of patients with gastric cancer with multiple primary cancers (GC-MPC) of three or more sites. Materials and Methods Between 1995 and 2009, 105,908 patients were diagnosed with malignancy at Severance Hospital, Yonsei University Health System. Of these, 113 (0.1%) patients with MPC of three or more sites were registered, and 41 (36.3%) of these were GC-MPC. We retrospectively reviewed the clinical data and overall survival using the medic

As power demands increase, development of the superconducting fault current limiter (SFCL) is being watched with interest. Many types of SFCLs using various superconducting materials have been developed. Especially, the FCL using coated conductor (CC) has been investigated actively at present. CCs have many advantages for the FCL application. YBCO materials used in CCs have a high n-value, and it is relatively easy to choose a matrix of the CC for high resistivity. If the CC has high resistivity

Coated conductor (CC) is recently inactively progress for the research and development, and its can be used various stabilizer for the specific superconducting applicat ions, coated conductor applied to superconducting fault current limiters(SFCLs) bypasses fault current to its stabilizer, where the surge is abruptly reduced; thus, stainless stel, which has large resistivity, can be a suitable stabilizer for SFCLs. Despite high n-value of the YBCO, CC stabilized with stainless steel did not effe

Large critical current is one of the prerequisites for the design of superconducting electrical equipments with large power capacity. To enlarge the critical current, multiple parallel connection is inevitable. In multiple parallel superconducting coils, the difference in normal resistance of each shunt leads to unequal current distribution, which may yield burnout. Therefore, uniform current distribution is required for a stable operation of multiple parallel superconducting coils. In this pape

Postoperative ileus (POI) is a delay in gastrointestinal transit following surgery that leads to various complications. There is limited understanding of its effective treatment options. CKD-495 and eupacidin are natural products licensed for treating mucosal lesions in acute and chronic gastritis; however, little is known about their effects on intestinal permeability. This study evaluated the effects of CKD-495, eupacidin, and its components (eupatilin and cinnamic acid) on intestinal per-meab

Background/Aims: Achalasia is an esophageal motility disorder characterized by dysphagia and noncardiac chest pain. Impairment of vagal function has been reported in achalasia. This study evaluated autonomic nervous system (ANS) dysfunctions in patients with achalasia to establish a correlation between an ANS dysfunction and the clinical symptoms of achalasia. Methods: Nineteen patients with achalasia (six males/13 females; mean age, 47.1±16.3 years) and 10 healthy controls (four males/six femal

원자층 증착법(ALD: atomic layer deposition)으로 150oC에서 성장된 zinc oxide (ZnO) 초박막의 두께 변화에따른 구조적, 전기적, 광학적 특성을 조사하였다. ZnO 박막을 증착하기 위해 금속 전구체와 반응물로 각각 diethylzinc와deionized water를 사용하였다. ALD 사이클 당 성장률은 150 oC에서 약 0.21 nm/cycle로 일정 하였으며, 50 사이클 이하의 샘플들은 초기 ALD 성장 단계에서 상대적으로 얇은 두께로 인하여 비정질 성질을 갖는 것으로 보였다. 100 사이클에서 200 사이클로 두께가 증가함에 따라 ZnO 박막의 결정성이 증가하였고 hexagonal wurtzite 구조를 보였다. 또한, ZnO 박막의 입자 크기가 ALD 사이클의 수의 증가에 따라 증가되었다. 전기적 특성 분석 결과 박막 두께의 증가에 따라서 비저항 값이 감소하였으며, 이는 박막 두께 증가에 따른 입자 크기 증가 및 결정성 개선으로 더 두꺼

Background: Immune-mediated inflammatory diseases (IMIDs) are associated with chronic inflammation that may increase fracture risk; however, their impact within specific populations, such as those with type 2 diabetes mellitus (T2DM), remains unclear. This study aimed to evaluate the association between IMIDs and fracture risk, leveraging a large, high-quality population-based cohort of patients with T2DM. Methods: A total of 2,120,900 patients with T2DM without a previous history of fractures w

Colonoscopy-related adverse events in older adults were linked to frailty and medication use and were not dependent on age. This novel risk score supports personalized decision-making when performing colonoscopies in older adults.

최근 서버급 어플리케이션의 메모리 요구량이 급증함에 따라 CXL (Compute Express Link) 기반의 이기종 메모리 시스템이 새로운 솔루션으로 제안되고 있다. 본 논문은 CXL을 통해 구성될 수 있는 이기종 메모리 시스템에서 서버급 어플리케이션이 remote 메모리로 인해 겪는 성능 저하를 분석하였다. CXL 메모리는 PCIe를 기반으로 하여 기존 DIMM보다 높은 확장성을 제공하지만, 메모리 접근시간이 길어 성능에 영향을 미칠 수 있다. 시장에서 CXL 메모리 카드를 구할 수 없으므로 본 연구는 이를 분석하기 위해 첫째, FPGA 환경에서 remote DRAM을 에뮬레이션하여 SPEC 벤치마크의 성능 민감도를 평가하였고, 둘째, 두 개의 소켓을 가진 서버에서 CXL 메모리를 모사하여 다양한 어플리케이션의 성능을 측정하였다. 실험 결과, remote 메모리 접근 빈도가 높은 어플리케이션일수록 성능 저하가 크게 발생하였으며, 다중 어플리케이션 환경에서도 이러한 현상이 두드러