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배민경 교수

Min-Kyung Bae

연세대학교 식품영양학과 · 의학

연구실 소개

배민경 교수 연구실은 간 섬유화, 헬리코박터 파일로리 감염에 의한 위염 및 암 발생 메커니즘, 그리고 항산화 물질의 면역 및 염증 조절 기전을 중심으로 한 영양소 및 천연물질의 생리적 기능을 연구하고 있습니다. 특히 비타민 D, 셀레늄, 타우린, 푸코자잔틴, 아스티아잔틴 등의 영양소와 천연 화합물이 면역 반응과 산화 스트레스에 미치는 영향을 기초 및 임상적 관점에서 탐구하고 있습니다. 연구는 주로 동물 모델과 간성 세포를 활용한 대사 재편성, DNA 손상 복구, 염증 반응 조절 메커니즘을 중심으로 진행됩니다.

간 섬유화헬리코박터 파일로리항산화 물질미세영양소세포 대사 재편성

연구 현황

논문 수
56
총 인용 수
1,595
최근 5년 논문
22
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
22총합
2020
2021
2022
2024
2026
5개년 연도별 피인용 수
685총합
20202021202220242026

주요 논문

15
1
리뷰|인용수 260·2020
The Role of Vitamin C, Vitamin D, and Selenium in Immune System against COVID-19
Minkyung Bae, Hyeyoung Kim
SJR Q1MoleculesOA

Low levels of micronutrients have been associated with adverse clinical outcomes during viral infections. Therefore, to maximize the nutritional defense against infections, a daily allowance of vitamins and trace elements for malnourished patients at risk of or diagnosed with coronavirus disease 2019 (COVID-19) may be beneficial. Recent studies on COVID-19 patients have shown that vitamin D and selenium deficiencies are evident in patients with acute respiratory tract infections. Vitamin D impro

Nutrition and DieteticsNursing
2
리뷰|인용수 189·2020
Health benefits of fucoxanthin in the prevention of chronic diseases
Minkyung Bae, Mi‐Bo Kim, Young‐Ki Park, Ji‐Young Lee
SJR Q2Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Nutrition and DieteticsNursing
3
논문|인용수 117·2018
Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners
Callie Farruggia, Mi‐Bo Kim, Minkyung Bae, Yoojin Lee, Tho X. Pham, Yue Yang, Myung Joo Han, Young‐Ki Park, Jiyoung Lee
SJR Q1The Journal of Nutritional Biochemistry
BiochemistryMedicine
4
논문|인용수 109·2016
Astaxanthin inhibits inflammation and fibrosis in the liver and adipose tissue of mouse models of diet-induced obesity and nonalcoholic steatohepatitis
Bohkyung Kim, Callie Farruggia, Chai Siah Ku, Tho X. Pham, Yue Yang, Minkyung Bae, Casey Wegner, Nicholas Farrell, Ellen Harness, Young‐Ki Park, Sung I. Koo, Ji‐Young Lee
SJR Q1The Journal of Nutritional Biochemistry
BiochemistryMedicine
5
리뷰|인용수 89·2017
Food components with antifibrotic activity and implications in prevention of liver disease
Minkyung Bae, Young‐Ki Park, Jiyoung Lee
SJR Q1The Journal of Nutritional BiochemistryOA
EpidemiologyMedicine
6
논문|인용수 70·2019
Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis
Tho X. Pham, Minkyung Bae, Mi‐Bo Kim, Yoojin Lee, Siqi Hu, Hyunju Kang, Young‐Ki Park, Ji‐Young Lee
SJR Q1Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseOA
Geriatrics and GerontologyMedicine
7
논문|인용수 62·2018
Biocompatible polymeric nanoparticles with exceptional gastrointestinal stability as oral delivery vehicles for lipophilic bioactives
Qiaobin Hu, Minkyung Bae, Erika Fleming, Ji‐Young Lee, Yangchao Luo
SJR Q1Food Hydrocolloids
Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
8
논문|인용수 52·2014
Protective effect of Korean Red Ginseng extract against Helicobacter pylori-induced gastric inflammation in Mongolian gerbils
Minkyung Bae, Sungil Jang, Joo Weon Lim, Jieun Kang, Eun‐Jung Bak, Jeong‐Heon Cha, Hyeyoung Kim
SJR Q1Journal of Ginseng ResearchOA

Helicobacter pylori-induced gastric inflammation includes induction of inflammatory mediators interleukin (IL)-8 and inducible nitric oxide synthase (iNOS), which are mediated by oxidant-sensitive transcription factor NF-κB. High levels of lipid peroxide (LPO) and increased activity of myeloperoxidase (MPO), a biomarker of neutrophil infiltration, are observed in H. pylori-infected gastric mucosa. Panax ginseng Meyer, a Korean herb medicine, is widely used in Asian countries for its biological a

SurgeryMedicine
9
논문|인용수 50·2015
Astaxanthin prevents and reverses the activation of mouse primary hepatic stellate cells
Yue Yang, Minkyung Bae, Bohkyung Kim, Young‐Ki Park, Sung I. Koo, Ji‐Young Lee
SJR Q1The Journal of Nutritional Biochemistry
HepatologyMedicine
10
논문|인용수 49·2018
Solid lipid-polymer hybrid nanoparticles prepared with natural biomaterials: A new platform for oral delivery of lipophilic bioactives
Taoran Wang, Minkyung Bae, Ji‐Young Lee, Yangchao Luo
SJR Q1Food Hydrocolloids
Food ScienceAgricultural and Biological Sciences
11
논문|인용수 47·2016
Histone deacetylase 9 plays a role in the antifibrogenic effect of astaxanthin in hepatic stellate cells
Yue Yang, Minkyung Bae, Young‐Ki Park, Yoojin Lee, Tho X. Pham, Swetha Rudraiah, José E. Manautou, Sung I. Koo, Ji‐Young Lee
SJR Q1The Journal of Nutritional Biochemistry
HepatologyMedicine
12
논문|인용수 38·2019
Astaxanthin attenuates the increase in mitochondrial respiration during the activation of hepatic stellate cells
Minkyung Bae, Yoojin Lee, Young‐Ki Park, Dong‐Guk Shin, Pujan Joshi, Seung-Hyun Hong, Nathan N. Alder, Sung I. Koo, Ji‐Young Lee
SJR Q1The Journal of Nutritional BiochemistryOA
HepatologyMedicine
13
리뷰|인용수 32·2022
Beneficial Effects of Taurine on Metabolic Parameters in Animals and Humans
Minkyung Bae, Kainat Ahmed, Jung‐Eun Yim
SJR Q1Journal of Obesity & Metabolic SyndromeOA

Taurine (2-aminoethanesulfonic acid) is a non-essential amino acid mainly obtained through diet in humans. Despite the lack of research on the health effects of taurine in animals and humans, it is widely used as a dietary supplement. Evidence from human and animal studies indicates that taurine is involved in conjugation of bile acids and regulation of blood pressure and has anti-oxidative, anti-inflammatory, and anti-obesogenic properties. Taurine can benefit both human and non-human animal he

Cell BiologyBiochemistry, Genetics and Molecular Biology
14
논문|인용수 14·2022
Fucoxanthin Attenuates the Reprogramming of Energy Metabolism during the Activation of Hepatic Stellate Cells
Minkyung Bae, Mi‐Bo Kim, Ji‐Young Lee
SJR Q1NutrientsOA

Hepatic stellate cells (HSC) play a major role in developing liver fibrosis. Upon activation during liver injury, activated HSC (aHSC) increase cell proliferation, fibrogenesis, contractility, chemotaxis, and cytokine release. We previously showed that aHSC have increased mitochondrial respiration but decreased glycolysis compared to quiescent HSC (qHSC). We also demonstrated that fucoxanthin (FCX), a xanthophyll carotenoid, has an anti-fibrogenic effect in HSC. The objective of this study was t

HepatologyMedicine
15
논문|인용수 13·2020
Astaxanthin inhibits the reduction of glycolysis during the activation of hepatic stellate cells
Minkyung Bae, Yoojin Lee, Tho X. Pham, Siqi Hu, Young‐Ki Park, Ji‐Young Lee
SJR Q1Life SciencesOA
HepatologyMedicine

대표 연구 분야

EpidemiologyHepatologyBiochemistrySurgeryMolecular BiologyNutrition and Dietetics

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