김민구 교수

Successful pregnancy requires an appropriate intrauterine immune response to the conceptus, which is a semiallograft within the uterus. We reported that swine leukocyte antigen-DQA (SLA-DQA), a major histocompatibility complex (MHC) class II gene, is expressed in the uterine endometrium at the time of conceptus implantation in pigs. Because MHC molecules play critical roles in the immune system, SLA-DQ was hypothesized to be involved in immune regulation during pregnancy. Therefore, we examined

We investigate the undetected error probabilities for bounded-distance decoding of binary primitive BCH codes when they are used for both error correction and detection on a binary symmetric channel. We show that the undetected error probability of binary linear codes can be simplified and quantified if the weight distribution of the code is binomial-like. We obtain bounds on the undetected error probability of binary primitive BCH codes by applying the result to the code and show that the bound

During embryo implantation in pigs, the uterine endometrium undergoes dramatic morphological and functional changes accompanied with dynamic gene expression. Since the greatest amount of embryonic losses occur during this period, it is essential to understand the expression and function of genes in the uterine endometrium. Although many reports have studied gene expression in the uterine endometrium during the estrous cycle and pregnancy, the pattern of global gene expression in the uterine endo

The uterine endometrium plays a critical role in regulating the estrous cycle and the establishment and maintenance of pregnancy in mammalian species. Many studies have investigated the expression and function of genes in the uterine endometrium, but the global expression pattern of genes and relationships among genes differentially expressed in the uterine endometrium during gestation in pigs remain unclear. Thus, this study investigated global gene expression profiles using microarray in pigs.

This paper investigates high rate systematic punctured convolutional codes based on Forney's (1970) results. High rate systematic punctured convolutional codes of rate-2/3 with constraint length 3/spl les/K/spl les/7 and rate-3/4 through 15/16 with K=7 are derived using the rate-1/2 best known nonsystematic convolutional codes. Weight spectra of newly discovered systematic punctured convolutional codes are provided and compared with the best known nonsystematic punctured codes. Simulation result

The purpose of vulnerability assessment is to determine when a disruption of service is likely to occur and to take steps to reduce the associated risk. With the growth of power systems, increases in grid complexity, and the trend toward deregulation, vulnerability assessment is imperative. Accurate vulnerability assessment is especially vital during heavy loading conditions and a vulnerability index is greatly needed to help the operator steer the system to viable conditions. In this paper, two

MOTIVATION: The small number of samples in many microarray experiments is a challenge for the correct identification of differentially expressed gens (DEGs) by conventional statistical means. Information from public microarray databases can help more efficient identification of DEGs. To model various experimental conditions of a public microarray database, we applied Gaussian mixture model and extracted bi- or tri-modal distributions of gene expression. Prior variance of Baldi's Bayesian framewo

The performance of detection methods is analyzed in the magneto-optical disc (MOD) system with (1,7) runlength limited (RLL) code. The peak detection, threshold detection, and partial response channel with maximum likelihood (PRML) detection are considered. The MOD system uses an SHG green laser and has a storage capacity of 4.2 Gbyte. The channel model is based on the implemented MOD system. The bit error probabilities of each detection method are obtained from simulation for three cases of onl

BACKGROUND: Identifying a regulatory module (RM), a bi-set of co-regulated genes and co-regulating conditions (or samples), has been an important challenge in functional genomics and bioinformatics. Given a microarray gene-expression matrix, biclustering has been the most common method for extracting RMs. Among biclustering methods, order-preserving biclustering by a sequential pattern mining technique has native advantage over the conventional biclustering approaches since it preserves the orde

The pig exhibits true epitheliochorial placentation, where the fetal membrane maintains attachment throughout pregnancy but does not invade into the maternal uterine endometrium. Accordingly, the expression and function of cell adhesion molecules are very important for embryo implantation and the establishment of pregnancy. In our recent microarray analysis, we found that activated leukocyte cell adhesion molecule (ALCAM) was expressed in the uterine endometrium during pregnancy in pigs. To bett