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Cisplatin, a commonly used chemotherapeutic agent, has a major limitation because of its nephrotoxicity. Recent studies have shown that cisplatin causes apoptotic cell death in renal tubule cells, but the underlying molecular mechanisms remain to be elucidated. In this study, cisplatin was found to induce apoptosis in a dose- and duration-dependent manner in cultured proximal tubule (LLC-PK1) cells, as evidenced by DNA laddering and TdT-mediated dUTP nick end-labeling assay. Pretreatment with th

The distances between the plumb lines from C2 and C7 were maintained but C2-C7 sagittal angle increased with aging.

During the COVID-19 pandemic, face masks have become limited in stock. Most of sterilization methods are not applicable for eliminating virus from face masks without compromising the filtration efficiency of the masks. In this study, using a human coronavirus (HCoV-229E) as a surrogate for SARS-CoV-2 contamination on KF94 face masks, we show that the virus loses its infectivity with a 4 log reduction when exposed for 10 s to 120 ppm ozone gas produced by a dielectric barrier discharge plasma gen

It seems that upper cervical levels are more likely to degenerate and to have more advanced degrees of degeneration than the lower cervical levels. As expected, age correlates with worsening degeneration. The proposed computed tomographic grading system for cervical facet arthrosis seemed to be reliable.

This paper reports on the study of repetitive nanosecond-pulsed discharge splitting of carbon dioxide (CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ) for the production of CO. Gas chromatography is used to analyze the composition of the reformed gas when CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> is exposed to high-voltage (15 kV) very short (10 ns) electrical discharges th

The total surface areas of human mastoid air cells were measured using digital CT scans. Using 24 normal ears, the lining of the mastoid air cells was digitally scanned, traced and analysed. The mean surface area of the mastoid air cell system was 167.0 cm2 and ranged from 74.78 to 330.01 cm2. The volume was also measured, the mean being 10.43 cm3 ranging from 6.25 to 20.52 cm3. The correlation coefficient between surface area and volume was 0.95. These results indicate that well pneumatized mas

Emission measurements are carried out to study the quenching of excited electronic states of nitrogen, N2∗, in nanosecond pulsed discharges in atmospheric pressure air and nitrogen. The results reveal that ground state N2 quenches N2(C) and N2(B) at rates less than dissociative quenching by ground state O2 by a factor of 4 and 2.5, respectively. Kinetic simulations with the inferred quench rates indicate that the dissociative quenching of N2∗ by O2 is responsible for 82% of atomic oxygen product