신명희 교수

The reference interval of TSH in Korea, where iodine intake is above the requirement, was 0.59-7.03 mIU/L and showed U-shaped change with age, which was a similar pattern to iodine intake. The reference interval of FT4 was 0.92-1.60 ng/dL. The geometric mean and upper limit of TSH were higher than those of Western populations, reflecting the paramount importance of iodine intake on thyroid function.

In this work, etching characteristics of TaN(200nm)∕HfO2(80nm) gate-stack structures on Si substrate were investigated by varying the process parameters such as BCl3∕(BCl3+Ar+O2) gas mixing ratio (Q), top-electrode power, dc self-bias voltage (Vdc), and overetch time in an inductively coupled plasma etcher. To understand the role of the etch gas chemistry, we measure the relative changes in the optical emission intensity of ions and radicals in the plasma as well as in the chemical binding state

CYP17 gene is involved in steroidogenesis and steroid metabolism. Epidemiologic results on the association between the CYP17 polymorphism and breast cancer risk have been inconsistent. We examined the association between the MspAI polymorphism at +27 relative to the start of transcription in the 5'-untranslated region of CYP17 gene and breast cancer risk in Korean women. Four hundred and sixty-two incident cases and 337 controls were recruited from three teaching hospitals in Seoul during 1994-2

The cancer incidence is increasing in Seoul, Korea, especially for the colorectum and prostate for men, and for the breast, colorectum, bronchus/lung and thyroid for women.

CYP17 gene is involved in steroidogenesis and steroid metabolism. Epidemiologic results on the association betwen the CYP17 polymor-phism and breast cancer risk have ben incon-sistent. We examined the association between the MspAI polymorphism at +27 relative to the start of transcription in the 5-untranslated re-gion of CYP17 gene and breast cancer risk in Korean women. Four hundred and sixty-two in-cident cases and 337 controls were recruited from three teaching hospitals in Seoul during 1994-

Even though RSI and RFS may be used as a general guideline for LPR management, pre-treatment RSI and RFS are not useful in predicting the patients' response to short-term PPI medication in the usual pattern of practice for LPR, which is mostly based on the physical evaluation and history taking.

Abstract Previous studies on dietary iodine intake and the risk of papillary thyroid cancer (PTC) have demonstrated inconsistent results. We aimed to evaluate the association between urinary iodine concentration (UIC), a surrogate biomarker for dietary iodine intake, and the risk of thyroid cancer stratified by sex and age in an iodine-sufficient area. A hospital-based case–control study was conducted in Seoul, South Korea. A total of 492 cases of newly diagnosed PTC and 595 controls were includ

Objectives. The aims of this study were to determine the benefits of short-term empirical proton pump inhibitor (PPI)medication on laryngopharyngeal reflux (LPR) and to determine whether scores on the reflux symptom index (RSI)and the reflux finding score (RFS) could be combined to identify subgroups of patients that will more likely to improve with this medication. Methods. Fifty-one Korean Otolaryngology Board-certified specialists joined this prospective, multi-center, and open-label observat

The incidence data (1991. 7. 11992. 6. 30) from the Implementation Study of Seoul Cancer Registry (ISSCR) were evaluated in terms of its completeness and validity. Two indicators for the completeness, Mortality/Incidence ratio (M/I ratio) and Age-specific Incidence Curve, showed fairy good registration throughout the age-sex specific strata, except the strata aged over 75 years old. The strata had very high M/I ratio (over 100%) and decreasing pattern of incidence, which suggested incomplete reg

The prevalence of metabolic syndrome was higher in KEs than in host country residents in Japan but not in China. Abdominal obesity and triglyceride are both discriminating and influential components in metabolic syndrome.

No single macronutrient was associated with BMI when all subjects were combined. However, when stratified by age, polyunsaturated fatty acid intake in younger women, and animal protein intake in older women, were positively associated with BMI. In the future, we recommend a larger study to confirm these results.