김명수 교수

Major concerns about donor safety cause controversy and limit the use of living donor liver transplantation to overcome organ shortages. The Korean Organ Transplantation Registry established a nationwide organ transplantation registration system in 2014. We reviewed the prospectively collected data of all 832 living liver donors who underwent procedures between April 2014 and December 2015. We allocated the donors to a left lobe group (n = 59) and a right lobe group (n = 773) and analyzed the re

Abstract Surface‐enhanced Raman scattering (SERS) of adenine, adenosine, 2′‐deoxyadenosine, 5′‐dAMP, 5′‐rAMP, 5′‐rADP and 5′‐rATP adsorbed on aqueous Ag sol has been investigated. A shift of the adenine ring breathing mode from 746 to 735 cm −1 with increasing adenine concentration is interpreted as reflecting the reorientation of adenine on the Ag surface. Such a shift is not observed for adenosine, 2′‐deoxyadenosine and 5′‐dAMP. SERS spectra of 5′‐rAMP, 5′‐rADP and 5′‐rATP can be obtained eith

The formation of inorganic nanoparticles has been understood based on the classical crystallization theory described by a burst of nucleation, where surface energy is known to play a critical role, and a diffusion-controlled growth process. However, this nucleation and growth model may not be universally applicable to the entire nanoparticle systems because different precursors and surface ligands are used during their synthesis. Their intrinsic chemical reactivity can lead to a formation pathwa

Developing Takagi-Sugeno fuzzy models by evolutionary algorithms mainly requires three factors: an encoding scheme, an evaluation method, and appropriate evolutionary operations. At the same time, these three factors should be designed so that they can consider three important aspects of fuzzy modeling: modeling accuracy, compactness, and interpretability. This paper proposes a new evolutionary algorithm that fulfills such requirements and solves fuzzy modeling problems. Two major ideas proposed

Abstract Surfac‐enhanced Raman spectra of L ‐tryptophanylglycine ( L ‐Trp‐Gly) and L ‐tryptophanylglycylglycine ( L ‐Trp‐Gly‐Gly) adsorbed on a silver surface were obtained. More detailed investigations than in a previous study on the surface‐enhanced Raman scattering from L ‐tryptophan ( L ‐ Trp) and glycyl‐ L ‐tryptophan (Gly‐ L ‐Trp) were also made. It was found that L ‐Trp and the above peptides adsorb on the silver surface via both the carboxylate (COO − ) and the amino (NH 2 ) groups. Inte

Recurrence increased to 44% with longer follow-up, but this did not limit the graft outcome. Recurrence was not affected by the kind of live donor. We conclude that live related or unrelated kidneys should be offered to IgAN patients.

We achieved excellent outcomes by using a donor exchange program as an option to reduce the donor organ shortage. However, the exchange donor program has no added benefit for blood-type O recipients.

These data suggest that genetic variations in TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, and KCNQ1 are associated with PTDM in Korea.

The purpose of this study was to investigate the efficacy of metformin as a radiosensitizer for use in combination therapy for human hepatocellular carcinoma (HCC). Three human HCC cell lines (Huh7, HepG2, Hep3B) and a normal human hepatocyte cell line were treated with metformin alone or with radiation followed by metformin. In vitro tests were evaluated by clonogenic survival assay, FACS analysis, western blotting, immunofluorescence and comet assay. Metformin significantly enhanced radiation

Congenital nephrotic syndrome (CNS) is a rare and uniformly fatal disease if it is not treated. Although renal transplantation has been a successful treatment, there remains a high mortality rate during the first year of life before transplantation. From 1979 to 1987, four patients with CNS, all of whom died before they could undergo renal transplantation were treated. On the basis of this clinical experience, early elective bilateral nephrectomy and dialysis for infants with CNS were initiated