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전명재 교수

Myung Jae Jeon

서울대학교 산부인과 · 의학

연구실 소개

전명재 교수 연구실은 여성의 골반저지지 기능과 관련된 생물학적 기전을 중심으로 연구를 진행하고 있습니다. 특히 난소기능저하, 호르몬 변화, 대사증후군 등이 여성의 성기능에 미치는 영향과 함께, 골반기저근지지조직의 콜라겐 대사 조절 메커니즘, 특히 HOXA11 및 미세RNA의 역할을 규명하고자 합니다. 또한 전통적 수술 후 골반기형 재발 위험 요인 분석과 함께, 생체재료 기반의 장기적인 안정성과 기능 회복을 위한 생체역학적 접근도 함께 연구하고 있습니다.

골반기저근지지성기능 저하콜라겐 대사HOXA11 전사 조절미세RNA

연구 현황

논문 수
108
총 인용 수
1,778
최근 5년 논문
25
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
25총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
120총합
20212022202320242025

주요 논문

15
1
논문|인용수 93·2008
Comparison of the treatment outcome of pubovaginal sling, tension-free vaginal tape, and transobturator tape for stress urinary incontinence with intrinsic sphincter deficiency
Myung Jae Jeon, Hyun-Joo Jung, Sue-Min Chung, Sei-Kwang Kim, Sang Wook Bai
SJR Q1American Journal of Obstetrics and GynecologyOA
RheumatologyMedicine
2
논문|인용수 59·2015
Risk factors for negative impacts on sexual activity and function in younger breast cancer survivors
Maria Lee, Yun Hwan Kim, Myung Jae Jeon
SJR Q1Psycho-Oncology

Chemo-related menopause was significantly associated with both sexual inactivity and dysfunction after treatment. Thyroid dysfunction and depression were risk factors for sexual inactivity in younger breast cancer survivors.

OncologyMedicine
3
논문|인용수 39·2008
Risk Factors for the Recurrence of Pelvic Organ Prolapse
Myung Jae Jeon, Sue Min Chung, Hyun Joo Jung, Sei Kwang Kim, Sang Wook Bai
SJR Q2Gynecologic and Obstetric InvestigationOA

BACKGROUND/AIMS: To investigate the risk factors for the recurrence of prolapse after traditional pelvic reconstructive surgery. METHODS: The medical records of 212 patients who received traditional restorative reconstructive surgeries for symptomatic pelvic organ prolapse from March 1999 to April 2006 were retrospectively analyzed. Recurrence was defined as any prolapse of stage II or greater according to the Pelvic Organ Prolapse Quantification system. The log-rank test and Cox regression of t

RheumatologyMedicine
4
논문|인용수 38·2011
Does Metabolic Syndrome Impair Sexual Function in Middle- to Old-Aged Women?
Yun Hwan Kim, Sun Mie Kim, Jinju Kim, In Seong Cho, Myung Jae Jeon
SJR Q1The Journal of Sexual Medicine

INTRODUCTION: To date, there are few studies dealing with the impact of metabolic syndrome (MS) on female sexual function, and the association between MS and female sexual dysfunction (FSD) in middle- to old-aged women remains unclear. AIM: To evaluate the impact of MS on sexual function in middle- to old-aged women. METHODS: From May 2009 to January 2010, we performed a cross-sectional study of sexually active women (≥ 40 years old) who visited a health-screening clinic. Comprehensive history t

Psychiatry and Mental healthMedicine
5
논문|인용수 29·2009
The Relationship Between COL3A1 Exon 31 Polymorphism and Pelvic Organ Prolapse
Myung Jae Jeon, Sue Min Chung, Jong Rak Choi, Hyun Joo Jung, Sei Kwang Kim, Sang Wook Bai
SJR Q1The Journal of UrologyOA

COL3A1 exon 31 polymorphism may have a role in determining the risk of pelvic organ prolapse in women with risk factors such as aging, vaginal childbirth and hypoestrogenism.

RheumatologyMedicine
6
논문|인용수 29·2009
A Long-Term Treatment Outcome of Abdominal Sacrocolpopexy
Myung Jae Jeon, Yeo Jung Moon, Hyun Joo Jung, Kyung Jin Lim, Hyo In Yang, Sei Kwang Kim, Sang Wook Bai
SJR Q2Yonsei Medical JournalOA

ASC provides durable pelvic support, however, it may be ineffective for alleviating pelvic floor dysfunction except for urinary urgency and voiding dysfunction, and it contains major complication risk that cannot be overlooked.

RheumatologyMedicine
7
논문|인용수 28·2015
MicroRNA‐30d and microRNA‐181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse
Myung Jae Jeon, Eun Jae Kim, Maria Lee, Hoguen Kim, Jong Rak Choi, Hee Dong Chae, Yeo Jung Moon, Sei Kwang Kim, Sang Wook Bai
SJR Q2Journal of Cellular and Molecular MedicineOA

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling may contribute to alterations in the biochemical strength of the USLs, leading to pelvic organ prolapse (POP). However, it is unknown how HOXA11 transcripts are regulated in the USLs. In this study, we

RheumatologyMedicine
8
논문|인용수 25·2007
Is hysterectomy or the use of graft necessary for the reconstructive surgery for uterine prolapse?
Myung Jae Jeon, Hyun Joo Jung, Hyun Jung Choi, Sei Kwang Kim, Sang Wook Bai
SJR Q2International Urogynecology JournalOA
RheumatologyMedicine
9
논문|인용수 23·2011
Association between metabolic syndrome and pelvic floor dysfunction in middle-aged to older Korean women
Yun Hwan Kim, Jinju Kim, Sun Mie Kim, Yunhee Choi, Myung Jae Jeon
SJR Q1American Journal of Obstetrics and Gynecology
RheumatologyMedicine
10
논문|인용수 22·2019
The effect of diagnosis-related group payment system on the quality of medical care for pelvic organ prolapse in Korean tertiary hospitals
Myung Jae Jeon, Sung Pil Choo, Young Hwa Kwak, Dong Wook Kim, Eui Hyeok Kim
SJR Q1PLoS ONEOA

The implementation of DRG in Korean tertiary hospitals has led to increase of outpatient visits and reduced surgical management for POP, which indicates that the uniform application of DRG influences the quality of care for POP patients.

RheumatologyMedicine
11
리뷰|인용수 18·2019
Surgical decision making for symptomatic pelvic organ prolapse: evidence-based approach
Myung Jae Jeon
SJR Q2Obstetrics & Gynecology ScienceOA

Surgery is the mainstay of treatment for symptomatic pelvic organ prolapse (POP), and a variety of procedures can be performed to correct POP. When deciding on the proper surgical procedure, the surgeon must take into consideration the individual patient's risk for surgical complication and prolapse recurrence and her preference. This review will discuss the key issues faced in the surgical decision-making process for POP and recommendations based on the current scientific evidence.

RheumatologyMedicine
12
논문|인용수 18·2009
A Long-Term Treatment Outcome of Abdominal Sacrocolpopexy
전명재, Yeo Jung Moon, Hyun Joo Jung, Kyung Jin Lim, Hyo In Yang, Sei Kwang Kim, Sang Wook Bai
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120090500060807

Purpose: The aim of this study was to evaluate the long-term treatment outcome and major complication rates of abdominal sacrocolpopexy (ASC). Materials and Methods: This retrospective study included 57 Korean women who underwent ASC with mesh for symptomatic uterine or vault prolapse and attended follow-up visits for at least 5 years. Forty-seven women with urodynamic stress incontinence concomitantly received a modified Burch colposuspension. The long-term anatomical and functional outcomes an

13
논문|인용수 16·2020
Risk factors for vaginal mesh erosion after sacrocolpopexy in Korean women
Tae Yeon Kim, Myung Jae Jeon
SJR Q1PLoS ONEOA

Premenopausal or menopausal women on ERT are at high risk for mesh erosion after SCP with type 1 polypropylene mesh, and two-thirds of mesh erosion cases require reoperation. This information should be incorporated into patient counseling and treatment decisions.

RheumatologyMedicine
14
논문|인용수 15·2014
Two-year urinary outcomes of sacrocolpopexy with or without transobturator tape: results of a prolapse-reduction stress test-based approach
Myung Jae Jeon, Ji Young Kim, Yeo Jung Moon, Sang Wook Bai, Eun‐Hee Yoo
SJR Q2International Urogynecology JournalOA
RheumatologyMedicine
15
논문|인용수 15·2021
Development and validation of a prediction model for bothersome stress urinary incontinence after prolapse surgery: A retrospective cohort study
Sumin Oh, Sungyoung Lee, Woo Yeon Hwang, Dong Hoon Suh, Myung Jae Jeon
SJR Q1BJOG An International Journal of Obstetrics & Gynaecology

OBJECTIVE: To develop and validate a prediction model for bothersome stress urinary incontinence after prolapse surgery and to compare it with an existing clinical prediction model (CUPIDO model). DESIGN: Retrospective cohort study. SETTING: Two tertiary hospitals in South Korea. POPULATION: A total of 1142 patients who underwent prolapse surgery with or without a concomitant midurethral sling. METHODS: To construct a prediction model, we performed logistic regression using both exhaustive and s

RheumatologyMedicine

대표 연구 분야

RheumatologyReproductive MedicineSurgeryPublic Health, Environmental and Occupational HealthEpidemiologyObstetrics and Gynecology

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