서명환 교수
Myung-Whan Suh
서울대학교 이비인후과 · 신경과학
연구실 소개
서명환 교수의 연구실은 신경영상 및 임상영상 기반의 해부학적 특성 분석을 중심으로, 아시아인과 유럽계 인종 간의 해부학적 차이를 규명하고 있습니다. 특히 뇌자극 치료(비침습적 뇌자극, rTMS)의 정확한 적용을 위해 인종별 해부학적 기준을 제시하며, 영상 유도 검사(예: vHIT)에서의 기구적 오차 요인 분석에도 주력하고 있습니다. 또한 청각 장애 환자의 시각적 언어 인지 기능과 뇌 기능성 영역의 변화를 전기생리학적 기법으로 탐색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The INV angle of the Asians measured by CT scan was 21.6 degrees +/-4.5 degrees . This value was significantly larger than that of the Caucasians, which has been reported to be 11.4 degrees +/-2.6 degrees (p<0.001). The INV angle measured endoscopically was 19.3 degrees +/-3.6 degrees . Reproducibility of the reconstructed CT method was good (p<0.001), while the reproducibility of the endoscopic method was poor (p=0.093). The correlation between the two methods was also poor (p=0.107).
OBJECTIVES: The aim of this study was to quantitatively measure the tightness of the goggle strap during the video head impulse test (vHIT) and to identify slippage-induced artifacts according to tightness. We aimed to elucidate the mechanism of faulty gain caused by goggle slippage and explain the typical artifacts associated with it. SUBJECTS AND METHODS: An endotracheal tube cuff manometer was coupled to the EyeSeeCam vHIT system (Interacoustics, Assens, Denmark) to monitor strap tightness. T
The risk factors for MT may be an age of over 45 yr and multiple recurrences. However, younger patients are more at risk of recurrence. A clear resection margin cannot guarantee a cure in RPA, and it seems that parotid pleomorphic adenomas slowly gain malignant characteristics after repeated recurrences.
The 10-20 EEG coordinates of the AC in Asians were significantly different to those in Caucasians. To accurately aim for the AC in Asians, it is recommended that the rTMS be located 1.8 cm superior to the T3 and 0.6 cm posterior to the T3-Cz line. However, because the spatial resolution of the TMS is rather low, this difference probably was not reflected in the treatment outcome.
Speechreading is a visual communicative skill for perceiving speech. In this study, we tested the effects of speech experience and deafness on the speechreading neural network in normal hearing controls and in two groups of deaf patients who became deaf either before (prelingual deafness) or after (postlingual deafness) auditory language acquisition. Magnetic signals from the cerebral cortex were recorded using a 306-channel magnetoencephalographic system. During magnetoencephalographic measurem
The L/S ratio was significantly increased in the PT group (5.01), compared with the control group (3.42). When the threshold value of the L/S ratio was assessed by the ROC method, 4.75 seemed to be the significant dissecting point. The sensitivity of this method was 0.64 and the specificity was 0.83.
The gap-startle paradigm has been used as a behavioral method for tinnitus screening in animal studies. This study aimed to investigate gap prepulse inhibition (GPI) of the auditory late response (ALR) as the objective response of the gap-intense sound paradigm in humans. ALRs were recorded in response to gap-intense and no-gap-intense sound stimuli in 27 healthy subjects. The amplitudes of the baseline-to-peak (N1, P2, and N2) and the peak-to-peak (N1P2 and P2N2) were compared between two avera
Early cochlear implantation was associated with better language development even within the critical period. This advantage may be recognized only when the effect of the age at implantation is separated from the effect of maturation/development.
OBJECTIVE: The purpose was to evaluate brain plasticity that contributes to speech performance after cochlear implantation (CI) in postlingual elderly (>60 years) patients. MATERIALS AND METHODS: Fifteen elderly postlingual deaf patients who underwent preoperative brain fluorodeoxyglucose positron emission tomography (FDG-PET) and were followed-up for more than 1 year after CI were included. The mean age of these patients was 64.6 years (range, 60-80 years). Based on their sentence score at 1 ye
Patients with SHLV are much more likely to have saccule/inferior vestibular nerve involvement than patients with VN.
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