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곽노균 교수

Nok-Kyun Kwo

한양대학교 기계공학부 · 공학

연구실 소개

곽노균 교수의 연구실은 전기화학적 유체역학과 나노유체학을 기반으로 한 혁신적인 미세유체 장치 개발에 주력하고 있습니다. 특히 이온 농도 극화(ion concentration polarization, ICP) 현상을 활용한 비압축형 생체분자 농축기, 종이 기반 진단 장치, 전기역학적 탈염 기술 등 실용적인 응용을 중심으로 연구를 전개하고 있습니다. 실험, 수치 시뮬레이션, 이론적 분석을 융합한 다학제적 접근을 통해 전기화학적 흐름 제어와 물질 분리의 새로운 원리를 제시하고 있습니다.

이온 농도 극화미세유체 장치비압축형 농축종이 기반 진단전기역학적 탈염

연구 현황

논문 수
91
총 인용 수
1,910
최근 5년 논문
28
주요 분야
공학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
28총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
225총합
20222023202420252026

주요 논문

15
1
논문|인용수 192·2012
Microscale electrodialysis: Concentration profiling and vortex visualization
Rhokyun Kwak, Guofeng Guan, Weng Kung Peng, Jongyoon Han
SJR Q1Desalination
Biomedical EngineeringEngineering
2
논문|인용수 170·2013
Shear Flow of an Electrically Charged Fluid by Ion Concentration Polarization: Scaling Laws for Electroconvective Vortices
Rhokyun Kwak, Van-Sang Pham, Kian Meng Lim, Jongyoon Han
SJR Q1Physical Review LettersOA

We consider electroconvective fluid flows initiated by ion concentration polarization (ICP) under pressure-driven shear flow, a scenario often found in many electrochemical devices and systems. Combining scaling analysis, experiment, and numerical modeling, we reveal unique behaviors of ICP under shear flow: a unidirectional vortex structure, its height selection, and vortex advection. Determined by both the external pressure gradient and the electric body force, the dimensionless height of the

Biomedical EngineeringEngineering
3
논문|인용수 154·2011
Continuous-Flow Biomolecule and Cell Concentrator by Ion Concentration Polarization
Rhokyun Kwak, Sung Jae Kim, Jongyoon Han
SJR Q1Analytical Chemistry

We present a novel continuous-flow nanofluidic biomolecule/cell concentrator, utilizing the ion concentration polarization (ICP) phenomenon. The device has one main microchannel which bifurcates into two channels, one for a narrow, concentrated stream and the other for a wider but target-free stream. A nanojunction [cation-selective material (Nafion)] is patterned along the tilted concentrated channel. Application of an electric field generates the ICP zone near the nanojunction so that biomolec

Biomedical EngineeringEngineering
4
논문|인용수 125·2016
Isolation of extracellular vesicle from blood plasma using electrophoretic migration through porous membrane
Siwoo Cho, Wonju Jo, Youhee Heo, Ji Yoon Kang, Rhokyun Kwak, Jaesung Park
SJR Q1Sensors and Actuators B Chemical
Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
논문|인용수 99·2016
Microfluidic paper-based biomolecule preconcentrator based on ion concentration polarization
Sung Il Han, Kyo Seon Hwang, Rhokyun Kwak, Jeong Hoon Lee
SJR Q1Lab on a Chip

Microfluidic paper-based analytical devices (μPADs) for molecular detection have great potential in the field of point-of-care diagnostics. Currently, a critical problem being faced by μPADs is improving their detection sensitivity. Various preconcentration processes have been developed, but they still have complicated structures and fabrication processes to integrate into μPADs. To address this issue, we have developed a novel paper-based preconcentrator utilizing ion concentration polarization

Biomedical EngineeringEngineering
6
논문|인용수 79·2016
Enhanced Salt Removal by Unipolar Ion Conduction in Ion Concentration Polarization Desalination
Rhokyun Kwak, Van-Sang Pham, Bumjoo Kim, Lan Chen, Jongyoon Han
SJR Q1Scientific ReportsOA

Chloride ion, the majority salt in nature, is ∼52% faster than sodium ion (DNa+ = 1.33, DCl- = 2.03[10(-9)m(2)s(-1)]). Yet, current electrochemical desalination technologies (e.g. electrodialysis) rely on bipolar ion conduction, removing one pair of the cation and the anion simultaneously. Here, we demonstrate that novel ion concentration polarization desalination can enhance salt removal under a given current by implementing unipolar ion conduction: conducting only cations (or anions) with the

Biomedical EngineeringEngineering
7
논문|인용수 59·2015
Paper-Based Flow Fractionation System Applicable to Preconcentration and Field-Flow Separation
Seokbin Hong, Rhokyun Kwak, Wonjung Kim
SJR Q1Analytical Chemistry

We present a novel paper-based flow fractionation system for preconcentration and field-flow separation. In this passive fluidic device, a straight channel is divided into multiple daughter channels, each of which is connected with an expanded region. The hydrodynamic resistance of the straight channel is predominant compared with those of expanded regions, so we can create steady flows through the straight and daughter channels. While the expanded regions absorb a great amount of water via capi

Biomedical EngineeringEngineering
8
논문|인용수 44·2017
Sheltering the perturbed vortical layer of electroconvection under shear flow
Rhokyun Kwak, Van-Sang Pham, Jongyoon Han
SJR Q1Journal of Fluid Mechanics

Sheltering of a perturbed vortical layer by a shear flow is a common method to control turbulence and transport in plasma physics. Despite the desire to exploit this phenomenon in wider engineering applications, shear sheltering has rarely been observed in general non-ionized fluids. In this study, we visualize this shear sheltering in a generic neutral-fluid situation in electromembrane desalination: electroconvection (EC) under the Hagen–Poiseuille flow initiated by ion concentration polarizat

Biomedical EngineeringEngineering
9
논문|인용수 39·2015
Spatiotemporally Defining Biomolecule Preconcentration by Merging Ion Concentration Polarization
Rhokyun Kwak, Ji Yoon Kang, Tae Song Kim
SJR Q1Analytical Chemistry

The ion concentration polarization (ICP) phenomenon at micronanofluidic interfaces has been extensively utilized to preconcentrate low-abundance biological samples. Although preconcentration by ICP is robust, its multiphysics phenomenon does not permit a clear prediction of the preconcentration conditions and sites. Here, we present a new method for spatiotemporally defining preconcentration, which can generate target-condensed plugs in a very specific region (<100 μm) regardless of the operatin

Biomedical EngineeringEngineering
10
논문|인용수 38·2024
Biporous silica nanostructure-induced nanovortex in microfluidics for nucleic acid enrichment, isolation, and PCR-free detection
Eunyoung Jeon, B. H. Koo, Suyeon Kim, Jieun Kim, Yeonuk Yu, Hyowon Jang, Minju Lee, Sung‐Han Kim, Taejoon Kang, Sang Kyung Kim, Rhokyun Kwak, Yong Shin
SJR Q1Nature CommunicationsOA

Efficient pathogen enrichment and nucleic acid isolation are critical for accurate and sensitive diagnosis of infectious diseases, especially those with low pathogen levels. Our study introduces a biporous silica nanofilms-embedded sample preparation chip for pathogen and nucleic acid enrichment/isolation. This chip features unique biporous nanostructures comprising large and small pore layers. Computational simulations confirm that these nanostructures enhance the surface area and promote the f

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
논문|인용수 37·2018
High-ionic-strength pre-concentration via ion concentration polarization for blood-based biofluids
Sung Il Han, Yong Kyoung Yoo, Junwoo Lee, Junwoo Lee, Cheonjung Kim, Kyungjae Lee, Tae Hoon Lee, Hyungsuk Kim, Dae Sung Yoon, Kyo Seon Hwang, Rhokyun Kwak, Jeong Hoon Lee
SJR Q1Sensors and Actuators B Chemical
Biomedical EngineeringEngineering
12
논문|인용수 37·2022
An epifluidic electronic patch with spiking sweat clearance for event-driven perspiration monitoring
Sangha Kim, Seongjin Park, Jina Choi, Wonseop Hwang, Sun-Ho Kim, In‐Suk Choi, Hyunjung Yi, Rhokyun Kwak
SJR Q1Nature CommunicationsOA

Sensory neurons generate spike patterns upon receiving external stimuli and encode key information to the spike patterns, enabling energy-efficient external information processing. Herein, we report an epifluidic electronic patch with spiking sweat clearance using a sensor containing a vertical sweat-collecting channel for event-driven, energy-efficient, long-term wireless monitoring of epidermal perspiration dynamics. Our sweat sensor contains nanomesh electrodes on its inner wall of the channe

Biomedical EngineeringEngineering
13
논문|인용수 35·2019
Microscale electrodeionization: In situ concentration profiling and flow visualization
Su-Dong Park, Rhokyun Kwak
SJR Q1Water Research
Biomedical EngineeringEngineering
14
논문|인용수 35·2009
Fabrication of Monolithic Bridge Structures by Vacuum‐Assisted Capillary‐Force Lithography
Rhokyun Kwak, Hoon Eui Jeong, Kahp Y. Suh
SJR Q1Small

Bridging the gap: Vacuum-assisted capillary force lithography (CFL) allows the fabrication of monolithic, suspended bridge structures (see picture) by exploiting partial curing kinetics and vacuum-assisted hydraulic filling. A small portion of the base microstructure (<4 µm) is molded to create a bridge structure by simply applying a nanoscale mold with the impression of channels, meshes, or circles.

Biomedical EngineeringEngineering
15
논문|인용수 31·2020
Controlling ion transport with pattern structures on ion exchange membranes in electrodialysis
Joonhyeon Kim, Sang‐Ha Kim, Rhokyun Kwak
SJR Q1Desalination
Biomedical EngineeringEngineering

대표 연구 분야

Biomedical EngineeringElectrical and Electronic EngineeringMolecular BiologyWater Science and TechnologySurfaces, Coatings and FilmsRenewable Energy, Sustainability and the Environment

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