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이평복 교수

Pyung Bok Lee

서울대학교 마취통증의학과 · 의학

연구실 소개

이평복 교수의 연구실은 척추 및 말초신경성 통증, 특히 척추수술 후 증후군, 천공성 척추관 섬유화, 만성 복합부정맥통증 증체후 등에 대한 비침습적 치료법 개발에 주력하고 있습니다. 전문적인 신경차단술, 경피적 축적성 분리술(PA), 스테로이드 및 캡사이신 기반 통증 완화 치료의 유효성과 안전성에 대한 임상 연구를 중심으로, 신경생리학적 기전과 통증의 심리사회적 영향까지 다각도로 접근하고 있습니다. 특히, 척추의 해부학적 변형이 신경근 기능에 미치는 영향과 약물 혼합 시 결정 형성 문제 등 실무적 문제 해결에도 기여하고 있습니다.

경피적 축적성 분리술만성 통증신경차단술스테로이드 혼합 안정성캡사이신 패치

연구 현황

논문 수
145
총 인용 수
1,182
최근 5년 논문
21
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
21총합
2021
2022
2024
2025
2026
5개년 연도별 피인용 수
66총합
20212022202420252026

주요 논문

15
1
논문|인용수 42·2008
Dermatome Variation of Lumbosacral Nerve Roots in Patients with Transitional Lumbosacral Vertebrae
Yang‐Hyun Kim, Pyung Bok Lee, Chul Joong Lee, Sang Chul Lee, Yong Chul Kim, Jin Do Huh
SJR Q1Anesthesia & Analgesia

BACKGROUND: The presence of a transitional vertebra can create difficulty in identifying the lumbar level corresponding to an exiting nerve root at the time of a spinal nerve block. We investigated the possibility that the muscle innervation pattern and sensory dermatomes of the lumbar nerve roots are altered when a lumbosacral transitional vertebra is present using electrical stimulation. METHODS: We determined the existence of transitional vertebrae using Castellvi's criteria. Patients having

PharmacologyMedicine
2
논문|인용수 34·2015
Is magnesium sulfate effective for pain in chronic postherpetic neuralgia patients comparing with ketamine infusion therapy?
Yang Hyun Kim, Pyung Bok Lee, Tak Kyu Oh
SJR Q1Journal of Clinical Anesthesia
PhysiologyMedicine
3
논문|인용수 32·2020
<p>Psychological Characteristics in Patients with Chronic Complex Regional Pain Syndrome: Comparisons with Patients with Major Depressive Disorder and Other Types of Chronic Pain</p>
Hye Youn Park, Ye Eun Jang, Sunghee Oh, Pyung Bok Lee
SJR Q1Journal of Pain ResearchOA

OBJECTIVE: This study investigated psychological characteristics of patients with chronic complex regional pain syndrome (CRPS) and examined relationships between psychosocial factors and pain severity. METHODS: In total, 76 patients with CRPS, 95 patients with other types of chronic pain, 171 healthy controls, and 66 patients with major depressive disorder (MDD) were included. Minnesota Multiphasic Personality Inventory (MMPI-2) profiles and scores on the Beck Depression Inventory and State-Tra

Anesthesiology and Pain MedicineMedicine
4
논문|인용수 23·2013
Evaluation of Prognostic Predictors ofPercutaneous Adhesiolysis Using a RaczCatheter for Post Lumbar Surgery Syndrome orSpinal Stenosis
Pyung Bok Lee
SJR Q1Pain PhysicianOA

BACKGROUND: Percutaneous adhesiolysis (PA) is considered to be a reasonable nonoperative treatment for herniation of intervertebral disc (HIVD), spinal stenosis, and post-lumbar-surgery syndrome (PLSS). The success of PA depends on the removal of epidural fibrosis and drug delivery to the target region. However, prognostic predictors of the effects of PA are not well known. OBJECTIVE: The aim of this study was to evaluate prognostic predictors of PA using a Racz catheter for patients with PLSS o

Pathology and Forensic MedicineMedicine
5
논문|인용수 23·2021
Non-Particulate Steroids (Betamethasone Sodium Phosphate, Dexamethasone Sodium Phosphate, and Dexamethasone Palmitate) Combined with Local Anesthetics (Ropivacaine, Levobupivacaine, Bupivacaine, and Lidocaine): A Potentially Unsafe Mixture
Eun Joo Choi, Dong-Hyun Kim, Woong Ki Han, Ho‐Jin Lee, Imhong Kang, Francis Sahngun Nahm, Pyung Bok Lee
SJR Q1Journal of Pain ResearchOA

Non-particulate steroids can form crystals upon combination with local anesthetics. Crystal formation may be caused by alkalinization of steroids. The mixing of ropivacaine or levobupivacaine and betamethasone sodium phosphate may require caution during an epidural steroid injection. Lidocaine or bupivacaine is recommended as a local anesthetic. Dexamethasone palmitate is a candidate for a mixture, but additional studies on its safety and effectiveness are needed.

SurgeryMedicine
6
논문|인용수 21·2017
Efficacy and Safety of 0.625% and 1.25%Capsaicin Patch in Peripheral Neuropathic Pain:Multi-Center, Randomized, and Semi-DoubleBlind Controlled Study
Pyung Bok Lee
SJR Q1Pain PhysicianOA

BACKGROUND: Topical capsaicin therapy may be of benefit in providing pain relief in patients with peripheral neuropathy. OBJECTIVES: To investigate the efficacy and safety of 0.625% (50 µg/cm2) and 1.25% (100 µg/cm2) capsaicin patches (CPs) compared to conventional 0.075% capsaicin cream or placebo patches in patients suffering from peripheral neuropathy. STUDY DESIGN: Early Phase II, multi-center, randomized, semi-double-blind, and placebo-controlled clinical trial. SETTING: Two medical college

Sensory SystemsNeuroscience
7
논문|인용수 20·2005
The Neurological Safety of Epidural Gabapentin in Rats: A Light Microscopic Examination
Sang Sik Choi, Yong Chul Kim, Young Jin Lim, Chul-Joong Lee, Pyung Bok Lee, Sang‐Cheol Lee, Woo-Seok Sim, Yoon‐La Choi
SJR Q1Anesthesia & Analgesia

Gabapentin acts primarily on the central nervous system. Therefore, we hypothesized that the direct epidural administration of gabapentin could have various advantages over its oral administration with respect to required dose, side effects, and efficacy. However, before administering gabapentin into the epidural space in a clinical setting, its neurotoxicity must be examined in animals. Thus, we evaluated neurotoxicity of epidural gabapentin by observing behavioral and sensory-motor changes, an

Pathology and Forensic MedicineMedicine
8
논문|인용수 20·2017
A Retrospective Study to Evaluate the Effect of Concentration of Hypertonic Saline on Efficacy and Safety of Epidural Adhesiolysis
Eun Joo Choi, Yong Jae Yoo, Pyung Bok Lee, Yong Chul Kim, Sang Chul Lee, Jee Youn Moon
SJR Q1Anesthesia & Analgesia

BACKGROUND: Percutaneous epidural adhesiolysis (PEA) is a minimally invasive procedure that is performed to relieve low back and/or lower limb pain secondary to adhesions or scarring in the epidural space that is refractory to conservative treatment. The optimal concentration of hypertonic saline might be an important factor in the safety and efficacy of PEA. We evaluated differences in the efficacy and safety of 2 concentrations of hypertonic saline (5% and 10%) used in lumbar PEA at our instit

Pathology and Forensic MedicineMedicine
9
논문|인용수 17·2015
Sympathetic Block as a New Treatment forLymphedema
Pyung Bok Lee
SJR Q1Pain PhysicianOA

BACKGROUND: Breast cancer-related lymphedema (BCRL) not only has physical implications, but also affects the quality of life in breast cancer survivors. Despite numerous studies of various therapies, the optimal treatment for BCRL is unknown. OBJECTIVE: In this study, we investigated the efficacy of sympathetic blockade (thoracic sympathetic ganglion block, [TSGB]) in treating BCRL. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center/teaching hospital. METHODS: TSGB was performe

OncologyMedicine
10
리뷰|인용수 16·2013
Peripheral Nerve Stimulation for the Treatment of Primary Headache
Pyung Bok Lee, Billy Huh
SJR Q1Current Pain and Headache Reports
Psychiatry and Mental healthMedicine
11
논문|인용수 14·2019
Kambin’s Triangle Approach versus Traditional Safe Triangle Approach for Percutaneous Transforaminal Epidural Adhesiolysis Using an Inflatable Balloon Catheter: A Pilot Study
Ho Young Gil, Sangmin Jeong, Hyunwook Cho, Eunjoo Choi, Francis Sahngun Nahm, Pyung Bok Lee
SJR Q1Journal of Clinical MedicineOA

Spinal stenosis is a common condition in elderly individuals. Many patients are unresponsive to the conventional treatment. If the transforaminal epidural block does not exert a sufficient treatment effect, percutaneous transforaminal epidural adhesiolysis (PTFA) through the safe-triangle approach using an inflatable balloon catheter can reduce the patients' pain and improve their functional capacity. We aimed to evaluate the safety and efficacy of the Kambin's-triangle approach for PTFA using a

Pathology and Forensic MedicineMedicine
12
논문|인용수 10·2014
Does Improvement in Epidurography Following Percutaneous Epidural Neuroplasty Correspond to Patient Outcome?
Jae Hun Kim, Hee Jin Jung, Francis Sahngun Nahm, Pyung Bok Lee
SJR Q1Pain Practice

OBJECTIVE: The positive effects of percutaneous epidural neuroplasty (PEN) likely result from elimination of fibrous tissue. However, a direct link between epidural adhesions and pain symptoms is debatable. We tested the hypothesis that epidurographic improvements correspond to improved patient outcome. METHODS: In this prospective study, patients with a filling defect on initial epidurography underwent PEN. Two weeks later, contrast agent distribution around the target area was assessed with re

Pathology and Forensic MedicineMedicine
13
논문|인용수 10·2014
Proteomic Identification of Altered Cerebral Proteins in the Complex Regional Pain Syndrome Animal Model
Francis Sahngun Nahm, Zee‐Yong Park, Sang‐Soep Nahm, Yong Chul Kim, Pyung Bok Lee
SJR Q2BioMed Research InternationalOA

BACKGROUND: Complex regional pain syndrome (CRPS) is a rare but debilitating pain disorder. Although the exact pathophysiology of CRPS is not fully understood, central and peripheral mechanisms might be involved in the development of this disorder. To reveal the central mechanism of CRPS, we conducted a proteomic analysis of rat cerebrum using the chronic postischemia pain (CPIP) model, a novel experimental model of CRPS. MATERIALS AND METHODS: After generating the CPIP animal model, we performe

PhysiologyMedicine
14
논문|인용수 8·2022
Effect of Nonsurgical Spinal Decompression on Intensity of Pain and Herniated Disc Volume in Subacute Lumbar Herniated Disc
Eunjoo Choi, Ho Young Gil, Jiyoun Ju, Woong Ki Han, Francis Sahngun Nahm, Pyung Bok Lee
SJR Q2International Journal of Clinical PracticeOA

Objective . Nonsurgical spinal decompression therapy (NSDT) is a conservative treatment for the lumbosacral herniated intervertebral disc (L‐HIVD). This study aimed to evaluate the clinical effectiveness of the NSDT and change in disc volume through magnetic resonance imaging (MRI) in subacute L‐HIVD. Methods . Sixty patients with subacute L‐HIVD were randomized into either the decompression group (group D, n = 30) or the nondecompression group (group N, n = 30). In group D, NSDT was performed t

Pathology and Forensic MedicineMedicine
15
논문|인용수 5·2022
Efficacy and safety of 5% lidocaine patches for postoperative pain management in patients undergoing unilateral inguinal hernia repair: study protocol for a prospective, double-blind, randomized, controlled clinical trial
Hong-min Ahn, Heung‐Kwon Oh, Duck‐Woo Kim, Sung‐Bum Kang, Bonwook Koo, Pyung Bok Lee
SJR Q2TrialsOA

BACKGROUND: Acute postoperative pain is a common complication of inguinal hernia repair. Pain management using local application of anesthetic agents over the skin surrounding the surgical incision may reduce the requirement for other pain medications. Targeted topical analgesics such as 5% lidocaine patches have been known to improve acute and chronic pain. However, the clinical effect of lidocaine patches on postoperative pain after inguinal hernia repair has not been studied, especially in pa

SurgeryMedicine

대표 연구 분야

SurgeryAnesthesiology and Pain MedicinePathology and Forensic MedicinePhysiologyPharmacologyEpidemiology

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