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김상현 교수

Sang-Hyun Kim

서울대학교 내과 · 의학

연구실 소개

김상현 교수의 연구실은 유연하고 내구성이 뛰어난 나노패턴화된 마찰전기 나노발전기 소자( WTNG) 개발을 핵심으로 하며, 특히 은 도금 섬유와 폴리디메틸실록산(PDMS) 나노구조를 활용한 고성능 에너지 수확 기술을 연구하고 있습니다. 또한, 갈릭산, 다이알릴 트리아릴 황화물(DATS) 등 천연물질이 면역염증 반응 및 산화 스트레스에 미치는 영향을 Nrf2 경로를 중심으로 규명하며 바이오의학적 응용 가능성도 탐색하고 있습니다. 이와 더불어, 심혈관 질환의 조기 진단을 위한 비침습적 영상 기술과 혈액 검사 기반의 정확도 향상 방안에 대해서도 연구를 진행하고 있습니다.

유연 나노발전기에너지 수확천연물질산화 스트레스심혈관 조기진단

연구 현황

논문 수
428
총 인용 수
10,779
최근 5년 논문
89
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
89총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
1,372총합
20212022202320242025

주요 논문

15
1
논문|인용수 707·2015
Nanopatterned Textile-Based Wearable Triboelectric Nanogenerator
Wanchul Seung, Manoj Kumar Gupta, Keun Young Lee, Kyung-Sik Shin, Ju‐Hyuck Lee, Tae Yun Kim, Sang‐Hyun Kim, Jianjian Lin, Jung Ho Kim, Sang‐Woo Kim, Sang‐Woo Kim, Sang‐Woo Kim
SJR Q1ACS Nano

Here we report a fully flexible, foldable nanopatterned wearable triboelectric nanogenerator (WTNG) with high power-generating performance and mechanical robustness. Both a silver (Ag)-coated textile and polydimethylsiloxane (PDMS) nanopatterns based on ZnO nanorod arrays on a Ag-coated textile template were used as active triboelectric materials. A high output voltage and current of about 120 V and 65 μA, respectively, were observed from a nanopatterned PDMS-based WTNG, while an output voltage

Biomedical EngineeringEngineering
2
논문|인용수 490·2005
Gallic Acid Inhibits Histamine Release and Pro-inflammatory Cytokine Production in Mast Cells
Sang‐Hyun Kim, Chang‐Duk Jun, Kyongho Suk, Byung‐Ju Choi, Hyunjeung Lim, Seun Ja Park, Seung Ho Lee, Hye‐Young Shin, Daekeun Kim, Tae‐Yong Shin
SJR Q1Toxicological Sciences

The discovery of drugs for the treatment of inflammatory allergic diseases such as, asthma, allergic rhinitis, and sinusitis is a very important subject in human health. Gallic acid (3,4,5-trihydroxybenzoic acid), a polyphenyl natural products from gallnut and green tea, is known to have anti-oxidant, anti-inflammatory, anti-microbial, and radical scavenging activities. The aim of the present study was to elucidate whether gallic acid modulates the inflammatory allergic reaction and to study its

Pathology and Forensic MedicineMedicine
3
리뷰|인용수 386·2019
Pulse Wave Velocity in Atherosclerosis
Hack‐Lyoung Kim, Sang‐Hyun Kim
SJR Q1Frontiers in Cardiovascular MedicineOA

Early detection of subclinical atherosclerosis is important to reduce patients' cardiovascular risk. However, current diagnostic strategy focusing on traditional risk factors or using risk scoring is not satisfactory. Non-invasive imaging tools also have limitations such as cost, time, radiation hazard, renal toxicity, and requirement for specialized techniques or instruments. There is a close interaction between arterial stiffness and atherosclerosis. Increased luminal pressure and shear stress

Cardiology and Cardiovascular MedicineMedicine
4
논문|인용수 385·2016
Boosting Power‐Generating Performance of Triboelectric Nanogenerators via Artificial Control of Ferroelectric Polarization and Dielectric Properties
Wanchul Seung, Hong‐Joon Yoon, Tae Yun Kim, Hanjun Ryu, Jihye Kim, Ju‐Hyuck Lee, Jeong Hwan Lee, Sang‐Hyun Kim, Sang‐Hyun Kim, Yun Kwon Park, Yun Kwon Park, Young Jun Park
SJR Q1Advanced Energy Materials

Low output current represents a critical challenge that has interrupted the use of triboelectric nanogenerators (TNGs) in a wide range of applications as sustainable power sources. Many approaches (e.g., operation at high frequency, parallel stacks of individual devices, and hybridization with other energy harvesters) remain limited in solving the challenge of low output current from TNGs. Here, a nanocomposite material system having a superior surface charge density as a triboelectric active ma

Biomedical EngineeringEngineering
5
리뷰|인용수 106·2014
Accuracy of Continuous Noninvasive Hemoglobin Monitoring
Sang‐Hyun Kim, Marc Lilot, Linda Murphy, Kulraj S. Sidhu, Zhaoxia Yu, Joseph Rinehart, Maxime Cannesson
SJR Q1Anesthesia & Analgesia

Although the mean difference between noninvasive Hb and central laboratory measurements was small, the wide limits of agreement mean clinicians should be cautious when making clinical decisions based on these devices.

HematologyMedicine
6
논문|인용수 90·2014
Keap1 Cysteine 288 as a Potential Target for Diallyl Trisulfide-Induced Nrf2 Activation
Sang‐Hyun Kim, Hee-Geum Lee, Sin‐Aye Park, Joydeb Kumar Kundu, Young‐Sam Keum, Young‐Nam Cha, Hye‐Kyung Na, Young‐Joon Surh
SJR Q1PLoS ONEOA

quinone oxidoreductase-1 (NQO1) in human gastric epithelial (AGS) cells. Furthermore, DATS administration by gavage increased the expression of HO-1 and NQO1 in C57BL/6 mouse stomach. Treatment with DATS increased the accumulation of nuclear factor-erythroid-2-related factor-2 (Nrf2) in the nucleus of cultured AGS cells and in mouse stomach in vivo. The DATS-induced expression of HO-1 and NQO1 was abrogated in the cells transiently transfected with Nrf2-siRNA or in the embryonic fibroblasts from

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 80·2011
Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells
Sung‐Whan Kim, Chae Eun Kim, Sang‐Hyun Kim
SJR Q2Biochemical and Biophysical Research Communications
Immunology and AllergyMedicine
8
논문|인용수 77·2009
Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-κB activation in mast cells
Sang‐Hyun Kim, Tae‐Yong Shin
SJR Q2Toxicology in Vitro
Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
논문|인용수 72·2009
Expression of Cancer-Testis Antigens MAGE-A3/6 and NY-ESO-1 in Non-Small-Cell Lung Carcinomas and Their Relationship with Immune Cell Infiltration
Sang‐Hyun Kim, Sang‐Yull Lee, Chang Hun Lee, Min Ki Lee, Young Dae Kim, Dong‐Hoon Shin, Kyung Un Choi, Jee Yeon Kim, Do Youn Park, Mee Young Sol
SJR Q1Lung
ImmunologyImmunology and Microbiology
10
논문|인용수 70·2014
The geometry of the curve graph of a right-angled Artin group
Sang‐Hyun Kim, Thomas Koberda
SJR Q2International Journal of Algebra and Computation

We develop an analogy between right-angled Artin groups and mapping class groups through the geometry of their actions on the extension graph and the curve graph, respectively. The central result in this paper is the fact that each right-angled Artin group acts acylindrically on its extension graph. From this result, we are able to develop a Nielsen–Thurston classification for elements in the right-angled Artin group. Our analogy spans both the algebra regarding subgroups of right-angled Artin g

Geometry and TopologyMathematics
11
논문|인용수 67·2006
Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages
Sang‐Hyun Kim, So-Young Lee, Kyoungho Suk, Hyun Bark, Chang-Duk Jun, Dae-Ki Kim, Cheol-Hee Choi, Teizo Yoshimura
SJR Q1Free Radical Biology and Medicine
Immunology and AllergyMedicine
12
논문|인용수 59·2003
Effects of Acute Hyperglycemia on Endothelium-Dependent Vasodilation in Patients with Diabetes Mellitus or Impaired Glucose Metabolism
Sang‐Hyun Kim, Kyung Woo Park, Yong‐Seok Kim, Seil Oh, In‐Ho Chae, Hyo‐Soo Kim, Cheol‐Ho Kim
Endothelium

Although impaired endothelial function is well known in patients with diabetes mellitus (DM), the precise mechanism and the factors that contribute to this dysfunction remain to be clarified. The authors examined the effect of acute hyperglycemia on endothelium-dependent vasodilation in patients with DM or impaired glucose metabolism in vivo by plethysmography. In eight patients with diabetes mellitus or impaired glucose metabolism, the vasodilatory response to acetylcholine at infusion rates of

Cardiology and Cardiovascular MedicineMedicine
13
논문|인용수 55·2020
Identification of pH-dependent removal mechanisms of lead and arsenic by basic oxygen furnace slag: Relative contribution of precipitation and adsorption
Sang‐Hyun Kim, Hyeonyong Chung, Seulki Jeong, Kyoungphile Nam
SJR Q1Journal of Cleaner Production
Environmental ChemistryEnvironmental Science
14
논문|인용수 51·2012
The Effectiveness of Extracorporeal Shock Wave Therapy vs. Local Steroid Injection for Management of Carpal Tunnel Syndrome
Hyun Seok, Sang‐Hyun Kim
SJR Q1American Journal of Physical Medicine & Rehabilitation

ESWT can be as useful as CS injection for relieving symptoms of carpal tunnel syndrome. Furthermore, in contrast to CS injection, it has the merit of being noninvasive.

Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 48·2008
Eupatilin inhibits H2O2-induced apoptotic cell death through inhibition of mitogen-activated protein kinases and nuclear factor-κB
Soyoung Lee, Myeungsu Lee, Sang‐Hyun Kim
SJR Q1Food and Chemical Toxicology
Molecular BiologyBiochemistry, Genetics and Molecular Biology

대표 연구 분야

Cardiology and Cardiovascular MedicineSurgeryMolecular BiologyPulmonary and Respiratory MedicineImmunologyRadiology, Nuclear Medicine and Imaging

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