박상철 교수

Recent investigations have revealed that the human microbiome plays an essential role in the occurrence of type 2 diabetes (T2D). However, despite the importance of understanding the involvement of the microbiota throughout the body in T2D, most studies have focused specifically on the intestinal microbiota. Extracellular vesicles (EVs) have been recently found to provide important evidence regarding the mechanisms of T2D pathogenesis, as they act as key messengers between intestinal microorgani

본 연구는 고용형태별 여행사종사원의 조직몰입에 영향을 미칠 수 있는 여러 잠재적 요인들 가운데 연구의 초점을 그들의 직무몰입 수준에 맞추고 있다. 직무몰입은 그 자체가 선행변수로서 여행사종사원의 조직몰입에 직접적인 영향을 미칠 수도 있지만, 기술다양성, 과업정체성, 과업중요성, 직무자율성, 피드백경로 등 직무특성과 조직몰입 간의 인과관계에서 매개적인 역할을 나타낼 가능성도 있기 때문이다. 만약 여행사종사원들의 객관적인 직무특성 요인들 이외에 직무에 대한 몰입수준이 그들의 조직몰입에 직접적 혹은 간접적 영향을 미친다면, 여행사관리자들은 이들 종사원의 직무몰입 수준을 고려한 관리적 차원의 정책을 수행해야 할 것이다. 분석 결과를 요약하면 다음과 같다. 첫째, 직무특성적인 요인들 중에서 과업정체성과 과업중요성 그리고 피드백경로가 여행사종사원의 조직몰입을 결정하는데 긍정적인 영향을 미치는 것으로 나타났다. 둘째, 직무특성적인 요인들 중에서 과업정체성, 과업중요성과 여행사종사원의 조직몰입 간

MOTIVATION: Ecological patterns of the human microbiota exhibit high inter-subject variation, with few operational taxonomic units (OTUs) shared across individuals. To overcome these issues, non-parametric approaches, such as the Mann-Whitney U-test and Wilcoxon rank-sum test, have often been used to identify OTUs associated with host diseases. However, these approaches only use the ranks of observed relative abundances, leading to information loss, and are associated with high false-negative ra

Foulbrood disease, which is caused by Paenibacillus larvae (American foulbrood) or Melissococcus plutonius (European foulbrood disease), is a major threat to honeybees ( Apis mellifera ) worldwide. Tetracycline derivatives have been used to control these bacteria, but resistant strains have evolved, and the antibiotic derivatives can adversely affect bee health. When foulbrood disease is discovered, beekeepers usually burn the bee hives and equipment. The aim of this study was to investigate the

The Holstein breed is the mainstay of dairy production in Korea. In this study, we evaluated the genomic prediction accuracy for body conformation traits in Korean Holstein cattle, using a range of π levels (0.75, 0.90, 0.99, and 0.995) in Bayesian methods (BayesB and BayesC). Focusing on 24 traits, we analyzed the impact of different π levels on prediction accuracy. We observed a general increase in accuracy at higher levels for specific traits, with variations depending on the Bayesian method

The global number of bees has recently declined. One reason is pathogenic microorganisms including Paenibacillus larvae, which causes American foulbrood disease, and Melissococcus plutonius, which causes European foulbrood disease. The aim of this study was to identify new antimicrobial agents against foulbrood disease. Broth-microdilution assays with 20 natural compounds were used to detect the in vitro antimicrobial activity against foulbrood disease, and MTT assays were performed to determine

Human sulfhydryl oxidase, catalyzing the conversion of either free or
\nbound thiol to disulfide compound, was isolated from human skin tissue to apparent
\nhomogeneity through multiple steps of ammonium sulfate salting-out, DEAE-cellulose
\nchromatography, CM-cellulose chromatography and ACA54 gel filtration. The enzyme
\nwas shown to have a molecular weight of 65 kDa and a specific activity of 8.39 x 103
\nUfmg protein. The specific polyclonal antibody was raised, with whic

The correlation and combining abilities about growth and flowering characters were studied in the F_1s of 8 crosses from the partial four-parent diallel cross in Lilium formolongi and Lilium formosanum which were pure lines (S_6). The plant height showed highly positive correlation with stem diameter or internode length, and negative correlation with flower height. The flower diameter showed highly positive correlation with number of leaves, and negative correlation with internode length or flow