이상학 교수

An improvement in the mechanical properties of a biomedical Ni-free Co-Cr-Mo alloy under as-cast condition has been examined by means of tensile tests and microstructure observations. The solubility of N in Co-Cr-Mo alloys increases with increasing Cr content from 29 to 34 mass%. This results in a significant improvement in mechanical properties such as yield stress, tensile strength, and fracture elongation. The improvement in the mechanical properties results from the γ phase stabilization and

The wrought Co–Cr–Mo alloys with C contents of 0.02, 0.09 and 0.18% (mass%) were fabricated by hot-forging process to study the influence of carbon contents on the microstructures and mechanical properties. The microstructures of Co–29Cr–6Mo–0.02C and Co–29Cr–6Mo–0.09C consist of equiaxed uniform grains which contain stacking faults, twins and ε martensite bands. No carbide found at inter- and intra-granular region. Co–29Cr–6Mo–0.18C consists of irregular grain sizes and carbide found at inter-

The effect of pre-heat treatments, followed by a hot forging process, on the microstructure and strength of Co–Cr–Mo alloys was investigated. Four pre-heat treatments were conducted at 1170, 1200, 1230 and 1260°C for three different time condition: 2, 6 and 15 h and then water cooled to room temperature. Tensile tests and XRD analyses were carried out on both as-cast alloy and heat-treated alloys. The volume fraction of retained γ phase increases with increasing the heat treatment temperature, s

High plasma adiponectin and resistin levels were predictors for all-cause mortality independent of other risk factors in patients with acute MI. These results confirmed and extended the positive correlations between these adipokines and mortality to a population consisting exclusively of MI.

BNP levels significantly correlated with LA volume index and E/E' in patients with lone AF, which indicates that the BNP level may reflect early left ventricular dysfunction and LA enlargement in this patient population.

Lower plasma level of EPA, but not DHA, was an independent predictor for all-cause-mortality in patients with AMI, but this relationship was significant only in female patients.

A novel fluorimetric method has been developed for the determination of microgram quantities of bovine serum albumin (BSA) based on its enhancement effect of Nile Blue fluorescence at 670 nm, caused by binding of Nile Blue to BSA to produce a stable water soluble complex. The binding constant of micromole Nile Blue-BSA complex was estimated by Scatchard plot method. Under the optimal conditions, the increased fluorescence intensity was linearly related to BSA concentration in the range of 0.5-12

The aim of this study was to compare the effects of 3 different statin regimens that have equivalent low-density lipoprotein cholesterol (LDL-C) lowering efficacy on the apolipoprotein B/A1 ratio and glucose metabolism. After a 4-week dietary lead-in, 90 hypercholeserolemic patients were randomly assigned to 1 of 3 treatment groups for 8 weeks: atorvastatin 20 mg, rosuvastatin 10 mg, or atorvastatin/ezetimibe 5 mg/5 mg. At drug treatment week 8, we compared the percentage changes in lipid parame

Familial hypercholesterolemia (FH) is a genetic disorder with an increased risk of early-onset coronary artery disease. Although some clinically diagnosed FH cases are caused by mutations in LDLR, APOB, or PCSK9, mutation detection rates and profiles can vary across ethnic groups. In this study, we aimed to provide insight into the spectrum of FH-causing mutations in Koreans. Among 136 patients referred for FH, 69 who met Simon Broome criteria with definite family history were enrolled. By whole

We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). The procedural success rates were 100 and 95%, respectively, in the SES and PES patients (p = 0.19). At the 6-month clinical follow-up, the event-free probability was 100% in the SES