이상화 교수
Sanghwa Lee
연세대학교 시스템생물학과 · 농업·생명과학
연구실 소개
이상화 교수의 연구실은 식물의 환경 스트레스 반응, 특히 고온 환경에 대한 생장 조절 메커니즘을 중심으로 연구를 진행하고 있습니다. 주로 열에 의한 생장 변화(온도형성)와 잎 노화 과정에서의 호르몬 신호 전달 및 세포자멸사 조절 체계를 분자생물학적·유전자적 접근으로 규명하고 있습니다. 특히 자라나는 식물의 줄기와 뿌리 성장 조절, 색소 분해와 관련된 대사 경로의 조절 메커니즘을 집중적으로 연구하고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15Jasmonic acid (JA) functions in plant development, including senescence and immunity. Arabidopsis thaliana CORONATINE INSENSITIVE 1 encodes a JA receptor and functions in the JA-responsive signaling pathway. The Arabidopsis genome harbors a single COI gene, but the rice (Oryza sativa) genome harbors three COI homologs, OsCOI1a, OsCOI1b, and OsCOI2. Thus, it remains unclear whether each OsCOI has distinct, additive, synergistic, or redundant functions in development. Here, we use the oscoi1b-1 kn
Plants respond to high ambient temperature by implementing a suite of morphological changes collectively termed thermomorphogenesis. Here we show that the above and below ground tissue-response to high ambient temperature are mediated by distinct transcription factors. While the central hub transcription factor, PHYTOCHROME INTERCTING FACTOR 4 (PIF4) regulates the above ground tissue response, the below ground root elongation is primarily regulated by ELONGATED HYPOCOTYL 5 (HY5). Plants respond
Effects of light exposure and vine microclimate on C<sub>13</sub>-norisoprenoid concentration in Cabernet Sauvignon grapes and wines were investigated by measuring the amounts of β-damascenone (megastigma-3,5,8-trien-7-one), TDN (1,1,6-trimethyl-1,2-dihydronaphthalene), and vitispirane (6,9-epoxy-3,5(13)-megastigmadiene) using gas chromatography-mass spectrometry. In grapes and wines, the most exposed treatment (all lateral and primary leaves removed) had the highest light intensity and temperat
Plant autophagy, one of the essential proteolysis systems, balances proteome and nutrient levels in cells of the whole plant. Autophagy has been studied by analysing Arabidopsis thaliana autophagy-defective atg mutants, but the relationship between autophagy and chlorophyll (Chl) breakdown during stress-induced leaf yellowing remains unclear. During natural senescence or under abiotic-stress conditions, extensive cell death and early yellowing occurs in the leaves of atg mutants. A new finding i
High ambient temperature due to global warming has a profound influence on plant growth and development at all stages of life cycle. Plant response to high ambient temperature termed thermomorphogenesis is characterized by hypocotyl and petiole elongation, and hyponastic growth at seedling stage. However, the molecular mechanism of thermomorphogenesis is still rudimentary. Here, we show that a set of four SUPPRESSOR OF PHYA-105 (SPA) genes is required for thermomorphogenesis. Consistently, SPAs
Plant growth and development are acutely sensitive to high ambient temperature caused in part due to climate change. However, the mechanism of high ambient temperature signaling is not well defined. Here, we show that HECATEs (HEC1 and HEC2), two helix-loop-helix transcription factors, inhibit thermomorphogenesis. While the expression of HEC1 and HEC2 is increased and HEC2 protein is stabilized at high ambient temperature, hec1hec2 double mutant showed exaggerated thermomorphogenesis. Analyses o
Within the nematode class C hromadorea, the suborder T ylenchina is an ecologically and morphologically diverse assemblage of nematodes that includes free‐living microbivores, fungivores and various types of plant parasites. A recent nematode classification system based largely on SSU r DNA phylogenetic trees classified suborder T ylenchina to include four infraorders: Panagrolaimomorpha, C ephalobomorpha, T ylenchomorpha and D rilonematomorpha, and phylogenetic relationships among species of th
Global warming will lead to significantly increased temperatures on earth. Plants respond to high ambient temperature with altered developmental and growth programs, termed thermomorphogenesis. Here we show that thermomorphogenesis is conserved in Arabidopsis, soybean, and rice and that it is linked to a decrease in the levels of the two macronutrients nitrogen and phosphorus. We also find that low external levels of these nutrients abolish root growth responses to high ambient temperature. We s
The Federated States of Micronesia consists of four states of Yap, Chuuk, Pohnpei and Kosrae, which are located in the West Pacific Ocean. In order to investigate molluscan fauna of Kosrae Island, field survey was made twice from 21st to 30th of January, 2011 and from 6th to 17th of January, 2012 for four localities including 10 intertidal and 14 subtidal zones of Kosrae Island. The mollusk samples collected were identified based on their morphological characteristics, comprising a total of 120
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