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이상화 교수

Sanghwa Lee

연세대학교 시스템생물학과 · 농업·생명과학

연구실 소개

이상화 교수의 연구실은 식물의 환경 스트레스 반응, 특히 고온 환경에 대한 생장 조절 메커니즘을 중심으로 연구를 진행하고 있습니다. 주로 열에 의한 생장 변화(온도형성)와 잎 노화 과정에서의 호르몬 신호 전달 및 세포자멸사 조절 체계를 분자생물학적·유전자적 접근으로 규명하고 있습니다. 특히 자라나는 식물의 줄기와 뿌리 성장 조절, 색소 분해와 관련된 대사 경로의 조절 메커니즘을 집중적으로 연구하고 있습니다.

온도형성잎 노화자율분해호르몬 신호전달고온 스트레스

연구 현황

논문 수
132
총 인용 수
2,051
최근 5년 논문
40
주요 분야
농업·생명과학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
40총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
504총합
20212022202320242025

주요 논문

15
1
논문|인용수 164·2020
Precipitation strengthening in naturally aged Al–Zn–Mg–Cu alloy
Sang‐Hwa Lee, Jae–Gil Jung, Sung‐Il Baik, David N. Seidman, Minseok Kim, Young‐Kook Lee, Kwangjun Euh
SJR Q1Materials Science and Engineering AOA
Aerospace EngineeringEngineering
2
논문|인용수 137·2014
Mutation ofOryza sativa CORONATINE INSENSITIVE 1b(OsCOI1b) delays leaf senescence
Sang‐Hwa Lee, Yasuhito Sakuraba, Taeyoung Lee, Kyu‐Won Kim, Gynheung An, Han Yong Lee, Nam‐Chon Paek
SJR Q1Journal of Integrative Plant BiologyOA

Jasmonic acid (JA) functions in plant development, including senescence and immunity. Arabidopsis thaliana CORONATINE INSENSITIVE 1 encodes a JA receptor and functions in the JA-responsive signaling pathway. The Arabidopsis genome harbors a single COI gene, but the rice (Oryza sativa) genome harbors three COI homologs, OsCOI1a, OsCOI1b, and OsCOI2. Thus, it remains unclear whether each OsCOI has distinct, additive, synergistic, or redundant functions in development. Here, we use the oscoi1b-1 kn

Insect ScienceAgricultural and Biological Sciences
3
논문|인용수 125·2021
Spatial regulation of thermomorphogenesis by HY5 and PIF4 in Arabidopsis
Sang‐Hwa Lee, Wenli Wang, Enamul Huq
SJR Q1Nature CommunicationsOA

Plants respond to high ambient temperature by implementing a suite of morphological changes collectively termed thermomorphogenesis. Here we show that the above and below ground tissue-response to high ambient temperature are mediated by distinct transcription factors. While the central hub transcription factor, PHYTOCHROME INTERCTING FACTOR 4 (PIF4) regulates the above ground tissue response, the below ground root elongation is primarily regulated by ELONGATED HYPOCOTYL 5 (HY5). Plants respond

Plant ScienceAgricultural and Biological Sciences
4
논문|인용수 106·2007
Vine Microclimate and Norisoprenoid Concentration in Cabernet Sauvignon Grapes and Wines
Sang‐Hwa Lee, Min Jae Seo, Marc Riu, Joseph P. Cotta, David E. Block, Nick Dokoozlian, Susan E. Ebeler
SJR Q2American Journal of Enology and Viticulture

Effects of light exposure and vine microclimate on C<sub>13</sub>-norisoprenoid concentration in Cabernet Sauvignon grapes and wines were investigated by measuring the amounts of β-damascenone (megastigma-3,5,8-trien-7-one), TDN (1,1,6-trimethyl-1,2-dihydronaphthalene), and vitispirane (6,9-epoxy-3,5(13)-megastigmadiene) using gas chromatography-mass spectrometry. In grapes and wines, the most exposed treatment (all lateral and primary leaves removed) had the highest light intensity and temperat

Plant ScienceAgricultural and Biological Sciences
5
논문|인용수 83·2014
Delayed degradation of chlorophylls and photosynthetic proteins in Arabidopsis autophagy mutants during stress-induced leaf yellowing
Yasuhito Sakuraba, Sang‐Hwa Lee, Ye-Sol Kim, Ohkmae K. Park, Stefan Hörtensteiner, Nam‐Chon Paek
SJR Q1Journal of Experimental BotanyOA

Plant autophagy, one of the essential proteolysis systems, balances proteome and nutrient levels in cells of the whole plant. Autophagy has been studied by analysing Arabidopsis thaliana autophagy-defective atg mutants, but the relationship between autophagy and chlorophyll (Chl) breakdown during stress-induced leaf yellowing remains unclear. During natural senescence or under abiotic-stress conditions, extensive cell death and early yellowing occurs in the leaves of atg mutants. A new finding i

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 66·2020
Effects of Ti addition on the microstructure and mechanical properties of Al–Zn–Mg–Cu–Zr alloy
Sang‐Hwa Lee, Jae–Gil Jung, Sung‐Il Baik, Sung Hyuk Park, Minseok Kim, Young‐Kook Lee, Kwangjun Euh
SJR Q1Materials Science and Engineering A
Aerospace EngineeringEngineering
7
논문|인용수 54·2020
SPAs promote thermomorphogenesis via regulating the phyB-PIF4 module in Arabidopsis
Sang‐Hwa Lee, Inyup Paik, Enamul Huq
SJR Q1DevelopmentOA

High ambient temperature due to global warming has a profound influence on plant growth and development at all stages of life cycle. Plant response to high ambient temperature termed thermomorphogenesis is characterized by hypocotyl and petiole elongation, and hyponastic growth at seedling stage. However, the molecular mechanism of thermomorphogenesis is still rudimentary. Here, we show that a set of four SUPPRESSOR OF PHYA-105 (SPA) genes is required for thermomorphogenesis. Consistently, SPAs

Plant ScienceAgricultural and Biological Sciences
8
논문|인용수 47·2024
Unravelling precipitation behavior and mechanical properties of Al–Zn–Mg–Cu alloy
Sang‐Hwa Lee, Tae–Young Ahn, Sung‐Il Baik, David N. Seidman, Seok-Jae Lee, Young‐Kook Lee, Kwangjun Euh, Jae-Gil Jung
SJR Q1Journal of Material Science and Technology
Aerospace EngineeringEngineering
9
논문|인용수 38·2021
An autoregulatory negative feedback loop controls thermomorphogenesis in Arabidopsis
Sang‐Hwa Lee, Ling Zhu, Enamul Huq
SJR Q1PLoS GeneticsOA

Plant growth and development are acutely sensitive to high ambient temperature caused in part due to climate change. However, the mechanism of high ambient temperature signaling is not well defined. Here, we show that HECATEs (HEC1 and HEC2), two helix-loop-helix transcription factors, inhibit thermomorphogenesis. While the expression of HEC1 and HEC2 is increased and HEC2 protein is stabilized at high ambient temperature, hec1hec2 double mutant showed exaggerated thermomorphogenesis. Analyses o

Plant ScienceAgricultural and Biological Sciences
10
논문|인용수 30·2015
Mitochondrial genomes advance phylogenetic hypotheses for Tylenchina (Nematoda: Chromadorea)
Jiyeon Kim, Sang‐Hwa Lee, Mohiuddin Gazi, Tae Ho Kim, Daewui Jung, Jae‐Yong Chun, Sanghee Kim, Tae‐Kun Seo, Chungoo Park, J. G. Baldwin, Steven A. Nadler, Joong‐Ki Park
SJR Q1Zoologica Scripta

Within the nematode class C hromadorea, the suborder T ylenchina is an ecologically and morphologically diverse assemblage of nematodes that includes free‐living microbivores, fungivores and various types of plant parasites. A recent nematode classification system based largely on SSU r DNA phylogenetic trees classified suborder T ylenchina to include four infraorders: Panagrolaimomorpha, C ephalobomorpha, T ylenchomorpha and D rilonematomorpha, and phylogenetic relationships among species of th

Plant ScienceAgricultural and Biological Sciences
11
논문|인용수 26·2024
Nutrient levels control root growth responses to high ambient temperature in plants
Sang‐Hwa Lee, Julia M. Showalter, Ling Zhang, Gaëlle Cassin-Ross, Hatem Rouached, Wolfgang Busch
SJR Q1Nature CommunicationsOA

Global warming will lead to significantly increased temperatures on earth. Plants respond to high ambient temperature with altered developmental and growth programs, termed thermomorphogenesis. Here we show that thermomorphogenesis is conserved in Arabidopsis, soybean, and rice and that it is linked to a decrease in the levels of the two macronutrients nitrogen and phosphorus. We also find that low external levels of these nutrients abolish root growth responses to high ambient temperature. We s

Plant ScienceAgricultural and Biological Sciences
12
논문|인용수 16·2025
Precipitation behavior and mechanical property anisotropy of Al–Zn–Mg–Cu alloy forgings
Sang‐Hwa Lee, Jung H. Shin, Seok-Jae Lee, Jae-Gil Jung
SJR Q1Materials Science and Engineering A
Aerospace EngineeringEngineering
13
논문|인용수 8·1998
Effects of Superoxide Dismutase on Riboflavin-Sensitized Photooxidation in Milk Systems
Sang‐Hwa Lee
SJR Q2Food Science and Biotechnology
Animal Science and ZoologyAgricultural and Biological Sciences
14
논문|인용수 8·2013
Marine Mollusk Fauna of Kosrae Island, Federated States of Micronesia
Sang‐Hwa Lee, Joong‐Ki Park
The Korean Journal of MalacologyOA

The Federated States of Micronesia consists of four states of Yap, Chuuk, Pohnpei and Kosrae, which are located in the West Pacific Ocean. In order to investigate molluscan fauna of Kosrae Island, field survey was made twice from 21st to 30th of January, 2011 and from 6th to 17th of January, 2012 for four localities including 10 intertidal and 14 subtidal zones of Kosrae Island. The mollusk samples collected were identified based on their morphological characteristics, comprising a total of 120

Aquatic ScienceAgricultural and Biological Sciences
15
논문|인용수 8·2024
Microstructural Evolution During Homogenization of Direct-Chill-Cast Al–Zn–Mg–Cu Alloy
Seonghyun Park, Junho Lee, Junhyub Jeon, Sang‐Hwa Lee, Jung H. Shin, Sangmin Choi, Seok-Jae Lee, Jae-Gil Jung
SJR Q1Metals and Materials International
Aerospace EngineeringEngineering

대표 연구 분야

Plant ScienceAerospace EngineeringFood ScienceOceanographyMaterials ChemistryAnimal Science and Zoology

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