안상민 교수

Background: Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae (CRE) significantly influences patient morbidity and mortality. We aimed to identify the characteristics, outcomes, and risk factors of mortality in adult patients with CRE bacteremia and elucidate the differences between carbapenemase-producing (CP)-CRE BSI and non-CP-CRE BSI. Methods: This retrospective study included 147 patients who developed CRE BSI between January 2016 and January 2019 at a large tert

BACKGROUND: Recently, a new scoring system was developed that uses the red blood cell distribution width (RDW), delta neutrophil index (DNI), and platelet count (PC) to predict mortality in patients with sepsis. We investigated whether a modified simple scoring system based on the RDW, DNI, and mean platelet volume-to-PC (MPV/PC) ratio could predict the mortality of patients with sepsis, and compared it to the previous scoring system. METHODS: We conducted a retrospective cohort study of 264 adu

The aim of this study was to describe the clinical and microbiological characteristics of infective arthritis and to analyze risk factors for Gram-negative bacterial infections that cause infective arthritis. Materials and Methods: Patients admitted between 2009 -2018 with infective arthritis in a single-tertiary hospital were evaluated retrospectively. Results: A total of 181 patients were enrolled in this study. Of them, 135 were native joint infection patients and 46 were prosthetic joint inf

자살예방을 위한 인식개선 캠페인은 국가적 자살예방대책의 핵심사업 중 하나이다. 본 연구는 자살예방 국가전략을 성공적으로 수행하고 있다고 평가되는 뉴질랜드·미국·아일랜드·스코틀랜드·호주의 5개국과 우리나라의 캠페인을 비교·분석하였다. 미국 보건복지부가 제시한 보건커뮤니케이션 캠페인 가이드라인을 토대로 각국의 캠페인을 (1) 목표의 명확성, (2) 표적화 전략의 적절성, (3) 메시지 전략의 적합성, (4) 이행의 효율성 측면에서 살펴보았다. 그 결과, 해외 캠페인들의 공통적 요소로 (1) 분명한 목표가 포함된 캠페인 명칭, (2) 사회 맥락을 고려한 캠페인 대상의 표적화, (3) 구체적인 행동지침을 포함한 슬로건, (4) 정부와 민간의 유기적 협력이 발견되었다. 이를 근거로 우리나라 캠페인이 발전하기 위해서는 보다 전략적 체계를 갖추고, 구체적인 대상에게 메시지가 전달될 수 있도록 하며, 보다 대중적인 매체를 활용하고, 민간 및 지방조직과의 유기적 협력을 강화하며, 체계적인 효과성 평

OBJECTIVES: We evaluated the vaccine effectiveness of monovalent XBB.1.5 vaccine against symptomatic COVID-19 infection, hospitalization, and the need for oxygen therapy in South Korea. DESIGN: This study employed a test-negative case-control design. COVID-19 test results in symptomatic subjects from six university hospitals across South Korea were collected (October 26-December 31, 2023). The adjusted absolute and relative vaccine effectiveness were assessed. RESULTS: In total, 5516 subjects we

Solid organ transplant (SOT) recipients are at significant risk of hepatitis B (HB) virus (HBV) reactivation (HBVr). Despite the clinical significance of HBVr after solid organ transplantation, data on the risk factors for HBVr and vaccine effectiveness in SOT recipients with resolved HBV infection are limited. This study evaluated the risk factors for HBVr and the seroconversion rates after HBV vaccination in SOT recipients. Patients who had undergone solid organ transplantation and those with

ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease caused by the SFTS virus (SFTSV). CP-COV03 is a novel antiviral candidate that significantly enhanced the bioavailability of niclosamide through inorganic-based drug delivery technology. The active pharmaceutical ingredient of CP-COV03, niclosamide, has been previously shown to possess broad-spectrum antiviral activity against over 30 different viruses in the in vitro tests. The aim of this study is to

Right-sided infective endocarditis (RSIE) is less common than left-sided infective endocarditis (LSIE) and exhibits distinct epidemiological, clinical, and microbiological characteristics. Previous studies have focused primarily on RSIE in patients with intravenous drug use. We investigated the characteristics and risk factors for RSIE in an area where intravenous drug use is uncommon. A retrospective cohort study was conducted at a tertiary hospital in South Korea. Patients diagnosed with infec

Prolonged COVID-19 was more frequent in lymphoma patients who received BR treatment followed by rituximab maintenance therapy and associated with unfavorable long-term outcomes and higher 1-year mortality.

Early CKRT initiation improved the survival of patients with sepsis-associated AKI. Initiation of CKRT should be considered as early as possible after sepsis-associated AKI onset, preferably within 6 hours.

정서적 자활에 대한 개념이 중요하게 논의되고 있으나, 실제 연구에서는 경제적 자활의 차원에만 초점을 맞추는 경향이 강했으며, 정서적 자활을 측정하는 개념에 대한 연구도 제한적으로 수행되고 있다. 따라서 본 연구는 고용희망척도(Employment Hope Scale)를 국내에 적용하여 자활 참여자의 정서적 자활을 평가하는 틀로서의 가능성을 검증하고자 정서적 자활에 영향을 미치는 탐색적 연구를 실시하였다. 이를 위해 전국 지역자활센터 458명을 대상으로 다중회귀분석을 실시하였다. 주요 연구결과로서, 회복탄력성, 자활생각, 방해요인 등이 정서적 자활에 영향을 미치는 것으로 나타났다. 즉, 자활 참여자의 심리 사회적 자원이 증가할수록 정서적 자활 수준이 높아지는 것이라 할 수 있다. 이를 토대로, 자활사업의 효과성 증진을 위한 정서적 자활의 중요성과 고용희망의 개념을 중심으로 한 교육의 필요성을 제언하였다.

T-cell count was observed for 8 months. This case report shows the first lenacapavir experience in Asia in a heavily treatment-experienced HIV patient with limited treatment options.

BACKGROUND: The implementation of antimicrobial stewardship programs (ASPs) in long-term care hospitals (LTCHs) is warranted to promote the appropriate use of antibiotics and improve patient outcomes. However, no studies have investigated physicians' understanding of antibiotic use and their perceived need for ASPs within these settings in Korea. In this study, we aimed to assess physicians' understanding of antibiotic use and their perceptions of ASPs in LTCHs. METHODS: In this multicenter cros

This is the first multicenter study to investigate the clinical and epidemiological characteristics of WLWH in Korea. The incidence and prevalence of diseases in women, including breast cancer, cervical cancer, and chronic comorbidities, are high in WLWH in Korea; therefore, further research and efforts are needed to manage these diseases.