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유성호 교수

Seong Ho Yoo

서울대학교 법의학과 · 의학

연구실 소개

유성호 교수의 연구실은 주로 간질환의 면역학적 기전과 관련된 사이토카인인 IL-22의 역할을 중심으로 연구를 진행하고 있습니다. 특히 만성 간염 등 간질환에서 IL-22의 발현이 어떻게 병태생리에 기여하는지에 대한 기전 규명을 목표로 하며, 이와 관련된 유전자 변형 마우스 모델을 활용한 기초 연구도 수행하고 있습니다. 또한, 소아 갑작스러운 수면 관련 사망(SIDS)의 위험 요인 분석 및 어르신들의 사회참여 활동, 특히 노령복지센터 이용에 영향을 주는 요인에 대해서도 심층적인 연구를 진행하고 있습니다. 이는 건강한 노화와 예방의학적 접근을 위한 정책적 근거를 마련하는 데 기여하고 있습니다.

IL-22만성 간질환SIDS노령복지센터면역학적 기전

연구 현황

논문 수
83
총 인용 수
1,834
최근 5년 논문
16
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
16총합
2019
2020
2021
2022
2024
5개년 연도별 피인용 수
216총합
20192020202120222024

주요 논문

15
1
논문|인용수 246·2011
PPARα Expression Protects Male Mice from High Fat–Induced Nonalcoholic Fatty Liver1–3
Mohamed A. Abdelmegeed, Seong Ho Yoo, Lauren E. Henderson, Frank J. Gonzalez, Kimberley J. Woodcroft, Byoung‐Joon Song
SJR Q1Journal of Nutrition
EpidemiologyMedicine
2
논문|인용수 244·2011
In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression
Ogyi Park, Hua Wang, Honglei Weng, Lionel Feigenbaum, Hai Li, Shi Yin, Sung Hwan Ki, Seong Ho Yoo, Steven Dooley, Fu‐Sheng Wang, Howard A. Young, Bin Gao
SJR Q1HepatologyOA

UNLABELLED: Interleukin-22 (IL-22), which acts as either a proinflammatory or anti-inflammatory cytokine in various disease models, is markedly up-regulated in chronic liver diseases, including hepatitis B and C. In this report, we demonstrate a strong correlation between IL-22 expression in the liver with active, inflammatory human liver disease. To clarify the role of IL-22 up-regulation in the pathogenesis of liver diseases, liver-specific IL-22 transgenic (IL-22TG) mice, under the control of

ImmunologyImmunology and Microbiology
3
논문|인용수 233·2012
Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
Mohamed A. Abdelmegeed, Atrayee Banerjee, Seong Ho Yoo, Sehwan Jang, Frank J. Gonzalez, Byoung‐Joon Song
SJR Q1Journal of Hepatology
EpidemiologyMedicine
4
논문|인용수 186·2013
CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
Mohamed A. Abdelmegeed, Atrayee Banerjee, Sehwan Jang, Seong Ho Yoo, Jun-Won Yun, Frank J. Gonzalez, Ali Keshavarzian, Byoung‐Joon Song
SJR Q1Free Radical Biology and MedicineOA
Pathology and Forensic MedicineMedicine
5
논문|인용수 94·2003
Expression of caveolin-1 is associated with poor prognosis of patients with squamous cell carcinoma of the lung
Seong Ho Yoo, Young Sik Park, Hyeong-Ryul Kim, Sook Whan Sung, Joo Hyun Kim, Young Soo Shim, Soong Deok Lee, Yoon‐La Choi, Min Kyung Kim, Doo Hyun Chung
SJR Q1Lung Cancer
Cell BiologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 49·2014
Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
Jun-Won Yun, Min-Jeong Son, Mohamed A. Abdelmegeed, Atrayee Banerjee, Timothy R. Morgan, Seong Ho Yoo, Byoung‐Joon Song
SJR Q1Free Radical Biology and MedicineOA
Pathology and Forensic MedicineMedicine
7
논문|인용수 28·2011
Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress
Seong Ho Yoo, Ogyi Park, Lauren E. Henderson, Mohamed A. Abdelmegeed, Kwan-Hoon Moon, Byoung‐Joon Song
SJR Q2Toxicology Letters
Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 28·1997
Elderly Koreans‘ tendency to live independently from their adult children: Adaptation to cultural differences in America
Seong Ho Yoo, Kyu‐taik Sung
SJR Q2Journal of Cross-Cultural Gerontology
Cultural StudiesSocial Sciences
9
논문|인용수 26·2005
Expression Patterns of Markers for Type II Pneumocytes in Pulmonary Sclerosing Hemangiomas and Fetal Lung Tissues
Seong Ho Yoo, Kyeong Cheon Jung, Joo Hyun Kim, Sook Whan Sung, Jin-Haeng Chung, Young Soo Shim, Soong Deok Lee, Doo Hyun Chung
SJR Q1Archives of Pathology & Laboratory Medicine

CONTEXT: Although the histogenesis of sclerosing hemangioma is currently not well understood, the tumor has been characterized by its 2 histologically different types of cells, namely, surface and polygonal cells. OBJECTIVE: To elucidate the origin of these cells, we analyzed samples from 15 cases of sclerosing hemangioma and 15 specimens of fetal lung tissue. DESIGN: We immunostained specimens from 15 cases of sclerosing hemangioma and 15 samples of fetal lung tissue using antibodies against th

Pulmonary and Respiratory MedicineMedicine
10
논문|인용수 24·2013
Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury
Seong Ho Yoo, Mohamed A. Abdelmegeed, Byoung‐Joon Song
SJR Q2Biochemical and Biophysical Research Communications
Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
논문|인용수 8·2017
Characteristics of completed suicide in different blood alcohol concentrations in Korea
Jae Won Lee, C. Hyung Keun Park, Eun Young Kim, Se Hyun Kim, Seong Ho Yoo, Yong Min Ahn
SJR Q1Forensic Science International
Clinical PsychologyPsychology
12
논문|인용수 8·2013
Sudden Infant Death Syndrome in Korea: A Retrospective Analysis of Autopsy-Diagnosed Cases
Seong Ho Yoo, Angela Julie Kim, Shin-Mong Kang, Han Young Lee, Joong-Seok Seo, Tae Jung Kwon, Kyung‐Moo Yang
SJR Q2Journal of Korean Medical ScienceOA

This study aimed to elucidate the demographic and sleeping environmental factors associated with sudden infant death syndrome (SIDS) in Korea. The autopsy reports of all SIDS cases reported to the National Forensic Service and Seoul National University College of Medicine between 1996 and 2008 were reviewed for data collection and analysis to identify the risk factors for SIDS. Analysis of the 355 SIDS cases reported within the study period revealed that of the 168 (47.3%) cases for which sleepi

Endocrine and Autonomic SystemsNeuroscience
13
논문|인용수 7·2015
Predictors of Senior Center Attendance in Korea: Findings From a National Analysis
Seong Ho Yoo
SJR Q2Journal of Social Service Research

Previous research on senior center attendance has focused mainly on the differences between senior center users and nonusers. However, this study explored the predictors distinguishing 3 categories of senior center users: users, nonusers, and former users. The data for this study were drawn from the 2004 National Survey on Living Status and Social Needs of the Korean Older Population, conducted jointly by the Korea Ministry of Health and Welfare and the Korea Institute for Health and Social Affa

DemographySocial Sciences
14
논문|인용수 6·2013
Sudden Infant Death Syndrome in Korea: A Retrospective Analysis of Autopsy-Diagnosed Cases
유성호, Angela Julie Kim, 강신몽, 이한영, 서중석, 권태정, 양경무
Journal of Korean Medical Science

This study aimed to elucidate the demographic and sleeping environmental factors associated with sudden infant death syndrome (SIDS) in Korea. The autopsy reports of all SIDS cases reported to the National Forensic Service and Seoul National University College of Medicine between 1996 and 2008 were reviewed for data collection and analysis to identify the risk factors for SIDS. Analysis of the 355 SIDS cases reported within the study period revealed that of the 168 (47.3%) cases for which sleepi

15
논문|인용수 4·2005
Factors affecting the frequency of senior center participation in Korea
Seong Ho Yoo, Chul Soo Kim
Asia Pacific Journal of Social Work and Development

This study examines the factors related to the frequency of senior center participation in Korea. The analyses are based on a sample of 316 Koreans, aged 65 and over, participating at a senior center in Chon-An City. The results show that gender, level of education, and health are statistically significant predictors of participation. That is, male Korean elderly, those who have a higher level of education, and those with better self-assessed health are more likely to participate at the center.

HealthSocial Sciences

대표 연구 분야

Radiology, Nuclear Medicine and ImagingMolecular BiologyPathology and Forensic MedicineEndocrine and Autonomic SystemsClinical PsychologyPhysiology

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