유성호 교수
Seong Ho Yoo
서울대학교 법의학과 · 의학
연구실 소개
유성호 교수의 연구실은 주로 간질환의 면역학적 기전과 관련된 사이토카인인 IL-22의 역할을 중심으로 연구를 진행하고 있습니다. 특히 만성 간염 등 간질환에서 IL-22의 발현이 어떻게 병태생리에 기여하는지에 대한 기전 규명을 목표로 하며, 이와 관련된 유전자 변형 마우스 모델을 활용한 기초 연구도 수행하고 있습니다. 또한, 소아 갑작스러운 수면 관련 사망(SIDS)의 위험 요인 분석 및 어르신들의 사회참여 활동, 특히 노령복지센터 이용에 영향을 주는 요인에 대해서도 심층적인 연구를 진행하고 있습니다. 이는 건강한 노화와 예방의학적 접근을 위한 정책적 근거를 마련하는 데 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15UNLABELLED: Interleukin-22 (IL-22), which acts as either a proinflammatory or anti-inflammatory cytokine in various disease models, is markedly up-regulated in chronic liver diseases, including hepatitis B and C. In this report, we demonstrate a strong correlation between IL-22 expression in the liver with active, inflammatory human liver disease. To clarify the role of IL-22 up-regulation in the pathogenesis of liver diseases, liver-specific IL-22 transgenic (IL-22TG) mice, under the control of
CONTEXT: Although the histogenesis of sclerosing hemangioma is currently not well understood, the tumor has been characterized by its 2 histologically different types of cells, namely, surface and polygonal cells. OBJECTIVE: To elucidate the origin of these cells, we analyzed samples from 15 cases of sclerosing hemangioma and 15 specimens of fetal lung tissue. DESIGN: We immunostained specimens from 15 cases of sclerosing hemangioma and 15 samples of fetal lung tissue using antibodies against th
This study aimed to elucidate the demographic and sleeping environmental factors associated with sudden infant death syndrome (SIDS) in Korea. The autopsy reports of all SIDS cases reported to the National Forensic Service and Seoul National University College of Medicine between 1996 and 2008 were reviewed for data collection and analysis to identify the risk factors for SIDS. Analysis of the 355 SIDS cases reported within the study period revealed that of the 168 (47.3%) cases for which sleepi
Previous research on senior center attendance has focused mainly on the differences between senior center users and nonusers. However, this study explored the predictors distinguishing 3 categories of senior center users: users, nonusers, and former users. The data for this study were drawn from the 2004 National Survey on Living Status and Social Needs of the Korean Older Population, conducted jointly by the Korea Ministry of Health and Welfare and the Korea Institute for Health and Social Affa
This study aimed to elucidate the demographic and sleeping environmental factors associated with sudden infant death syndrome (SIDS) in Korea. The autopsy reports of all SIDS cases reported to the National Forensic Service and Seoul National University College of Medicine between 1996 and 2008 were reviewed for data collection and analysis to identify the risk factors for SIDS. Analysis of the 355 SIDS cases reported within the study period revealed that of the 168 (47.3%) cases for which sleepi
This study examines the factors related to the frequency of senior center participation in Korea. The analyses are based on a sample of 316 Koreans, aged 65 and over, participating at a senior center in Chon-An City. The results show that gender, level of education, and health are statistically significant predictors of participation. That is, male Korean elderly, those who have a higher level of education, and those with better self-assessed health are more likely to participate at the center.
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