이슬기 교수
Seul Gi Lee
연세대학교 의생명과학부 · 의학
연구실 소개
이슬기 교수의 연구실은 내분비외과 및 갑상선암 치료 분야에서 세계적으로 주목받는 전문 연구를 수행하고 있습니다. 특히 로봇을 활용한 갑상선절제술(로봇 갑상선절제술)의 기술적 혁신과 기존 수술법의 한계를 극복하기 위한 기술 개발에 초점을 맞추고 있으며, 갑상선암 환자의 옹종 예후 예측 및 개인화된 치료 전략 수립을 위한 임상 기반의 정밀의료 연구도 활발히 진행되고 있습니다. 또한 갑상선암 환자의 장기적 생존율과 재발 위험도를 정량적으로 평가하기 위한 새로운 위험도 분류 체계와 림프절 비율(LNR)을 활용한 예측 모델 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15BACKGROUND: Since the use of robot systems in thyroid surgery was introduced in 2007, we have advanced a novel method of robotic thyroidectomy (RT) using a gasless transaxillary approach (TAA). We report our experience with this technique and detail the surgical outcome of 5000 robotic thyroidectomies. METHODS: From October 2007 to May 2016, we successfully performed 5000 robotic thyroidectomies using a gasless TAA at the Department of Surgery, Yonsei University Health System. The medical record
Purpose: This study was done to verify effects of a self-directed feedback practice using smartphone videos on nursing students'basic nursing skills, confidence in performance and learning satisfaction. Methods: In this study an experimental study with a posttestonly control group design was used. Twenty-nine students were assigned to the experimental group and 29 to the controlgroup. Experimental treatment was exchanging feedback on deficiencies through smartphone recorded videos of nursing pra
BACKGROUND: Recent guidelines advocate unilateral thyroidectomy for low-risk 1-cm to 4-cm differentiated thyroid cancer (DTC). This study was designed to examine the association between the extent of thyroidectomy and oncologic outcomes in patients with 1-cm to 4-cm DTC. MATERIALS AND METHODS: From April 1978 to December 2011, 16 057 patients with DTC underwent thyroidectomy at Yonsei University Hospital. Among them, 5266 (32.8%) patients were classified as having 1-cm to 4-cm DTC and were enrol
BACKGROUND: The 2015 American Thyroid Association (ATA) management guidelines for adult patients with differentiated thyroid cancer propose the use of the modified initial risk stratification and response to therapy re-stratification systems. This study was conducted to validate the practicality of the revised guidelines for predicting tumor recurrence in patients with differentiated thyroid cancer. METHODS: Patients with papillary thyroid cancer (n = 2425) who underwent total thyroidectomy with
PURPOSE: This study was done to verify effects of a self-directed feedback practice using smartphone videos on nursing students' basic nursing skills, confidence in performance and learning satisfaction. METHODS: In this study an experimental study with a post-test only control group design was used. Twenty-nine students were assigned to the experimental group and 29 to the control group. Experimental treatment was exchanging feedback on deficiencies through smartphone recorded videos of nursing
Abstract Recently, the 2015 American Thyroid Association (ATA) risk stratification and the 8 th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system were released. This study was conducted to assess the clinical value of the lymph node ratio (LNR) as a predictor of recurrence when integrated with these newly released stratification systems, and to compare the predictive accuracy of the modified systems with that of the newly rele
The long-term treatment outcome of PTMC without LNM was favorable even if the recurrence occurs during follow-up period compared with that of PTMC with LNM. It should be noted that AS might be able to cause poor prognosis due to clinically apparent LNM.
Regional lymph node (LN) metastasis has a significant impact for prediction of recurrence in patients with papillary thyroid cancers (PTC); however, the prognostic value of the lymph node ratio (LNR), which is defined as the ratio of the number of metastatic LNs to the total number of investigated LNs, is controversial. In this study, we determined the optimal cut-off values of LNRs for the prediction of recurrence in PTC patients.This large cohort study retrospectively evaluated 2294 patients w
Background and Objectives: We sought to investigate an anti-atherosclerotic and anti-inflammatory effect of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in normoglycemic atherosclerotic rabbit model. Methods: Male New Zealand white rabbits (n=26) were fed with a 1% high-cholesterol diet for 7 weeks followed by normal diet for 2 weeks. After balloon catheter injury, the rabbits were administered with the Dapagliflozin (1mg/kg/day) or control-medium for 8 weeks (n=13 for each group). All les
지난 메르스 사태의 경험에 비추어 볼 때 감염병의 확산과 같은 위험 상황에서 정부의 투명한정보공개는 정부대응의 효과를 높이는 데 필수적이다. 이에 본 연구는 코로나19 위험 상황에서정부와 국민 간 이루어지는 리스크 커뮤니케이션이 정부신뢰에 미치는 영향을 확인하고, 이 관계가 전자정부 역량에 의해 어떻게 변화하는지 분석한다. 이를 위하여 연세대학교 미래정부연구센터가 실시한 ‘2020년 초변화사회의 신뢰받는 미래정부 통계조사’ 자료를 활용하여 다중회귀분석을 수행하였다. 분석결과, 코로나19 관련 정보의 신뢰성과 정확성, 전달의 신속성으로구성된 리스크 커뮤니케이션은 정부신뢰에 긍정적인 영향을 미치며 이 관계는 정보와 시스템, 서비스 역량으로 구성된 전자정부의 역량에 의해 강화되었다. 본 연구는 기존 리스크 커뮤니케이션과 정부신뢰의 논의에서 통로로서의 전자정부의 역할을 재확인하였으며, 코로나19라는 실제 재난 상황에서 수집한 국민의 인식을 기초로 실증하였다는 데 의의가 있다.
OBJECTIVE: Tumor location in papillary thyroid microcarcinoma (PTMC) might determine tumor outgrowth from the thyroid gland. However, the clinical implications of tumor location and minimal extrathyroid extension (mETE) have not been well elucidated. We aimed to investigate the relationship between tumor location and mETE to predict the aggressiveness of PTMC. METHODS: A total of 858 patients with PTMC were grouped according to tumor location on ultrasonography: central (cPTMC) and peripheral PT
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