최승홍 교수

Objective: The purpose of this study was to differentiate true progression from pseudoprogression of glioblastomas treated with concurrent chemoradiotherapy (CCRT) with temozolomide (TMZ) by using histogram analysis of apparent diffusion coefficient (ADC) and normalized cerebral blood volume (nCBV) maps. Materials and Methods: Twenty patients with histopathologically proven glioblastoma who had received CCRT with TMZ underwent perfusion-weighted imaging and diffusion-weighted imaging (b = 0, 100

This paper proposes a feature extraction method to effectively handle the textural characteristics in images with defects in cold rolled strips. An adaptive wavelet packet scheme is developed to produce the optimum number of features automatically through subband coding gain. Also four classical entropy features in the images with defects are used as local features in the spatial domain. A neural network is used to classify the defects from these features. Experiments with real image data show g

Balanced steady-state free precession (bSSFP) is a highly efficient pulse sequence that is known to provide the highest signal-to-noise ratio per unit time. Recently, bSSFP is getting increasingly popular in both the research and clinical communities. This review will be focusing on the application of the bSSFP technique in the context of probing the physiological and functional information. In the first part of this review, the basic principles of bSSFP are briefly covered. Afterwards, recent d

Objective: We wanted to investigate the accuracy of contrast-enhanced MR imaging for the detection of lymph node metastases in a head and neck cancer rabbit model. Materials and Methods: The metastatic lymph node model we used was created by inoculating VX2 tumors into the auricles of six New Zealand White rabbits. T1-weighted MR images were obtained before and after injecting gadopentetate dimeglumine at three weeks after tumor cell inoculation. The sizes, signal intensity ratios (i.e., the pos

To determine whether histogram values of the normalized apparent diffusion coefficient (nADC) and normalized cerebral blood volume (nCBV) maps obtained in contrast-enhancing lesions detected on immediate post-operative MR imaging can be used to predict the patient response to concurrent chemoradiotherapy (CCRT) with temozolomide (TMZ). Twenty-four patients with GBM who had shown measurable contrast enhancement on immediate post-operative MR imaging and had subsequently undergone CCRT with TMZ we

The accurate identification and characterization of lymph nodes by modern imaging modalities has important therapeutic and prognostic significance for patients with newly diagnosed cancers. The presence of nodal metastases limits the therapeutic options, and it generally indicates a worse prognosis for the patients with nodal metastases. Yet anatomic imaging (CT and MR imaging) is of limited value for depicting small metastatic deposits in normal-sized nodes, and nodal size is a poor criterion w

Objective: To evaluate the temporal evolution and diagnostic values of the diffusion tensor imaging (DTI) and the high b value diffusion weighted imaging (DWI) in the early permanent and transient cerebral ischemia. Materials and Methods: For permanent or 30-minute transient-ischemia induced 30 rats, DTI and DWIs at both high b (b = 3000 s/mm2) and standard b value (b = 1000 s/mm2) were obtained at the following conditions: at 15, 30, 45, 60 minutes after the occlusion of what for hyperacute per

We investigated the safety and clinical applicability of 7.0 Tesla (T) brain magnetic resonance imaging (MRI) in patients with brain tumors. Twenty-four patients with intraaxial or extraaxial brain tumors were enrolled in this study. 7.0T MRIs of T2*-weighted axial and T1-weighted coronal or sagittal images were obtained and compared with 1.5T brain MRIs. The T2*-weighted images from 7.0T brain MRI revealed detailed microvasculature and the internal contents of supratentorial brain tumors better

Objective: To describe detailed clinical and radiological features of the pandemic H1N1 2009 influenza viral infection among healthy young males in a semiclosed institutionalized setting. Materials and Methods: A total of 18 patients confirmed with the pandemic H1N1 2009 influenza virus infection from July 18 to July 30, 2009 were enrolled in this study. Each patient underwent an evaluation to determine detailed clinical and radiological features. Results: All patients presented with high fever

Background: There has been no practical guidelines for the management of patients with centralnervous system (CNS) tumors in Korea for many years. Thus, the Korean Society for Neuro-Oncology(KSNO), a multidisciplinary academic society, started to prepare guidelines for CNS tumors from February2018. Methods: The Working Group was composed of 35 multidisciplinary medical experts in Korea. References were identified through searches of PubMed, MEDLINE, EMBASE, and Cochrane CENTRALusing specific and

Gastrointestinal stromal tumors, formerly classified as leiomyomas or leiomyosarcomas, constitute the most common form of mesenchymal tumor in the gastrointestinal tract, with the stomach being the most common site of origin (1). The diagnosis of these tumors became feasible through the application of CD117 immunohistochemistry, which allows these neoplasms to be distinguished from leiomyomas or leiomyosarcomas (2). Moreover, the recently developed KIT-tyrosine kinase inhibitor (STI 571, imatini

Purpose: We evaluated hemodynamic significance of stenosis on magnetic resonance angiography (MRA) using acetazolamideperfusion single photon emission computed tomography (SPECT). Materials and Methods: Of 171 patients, stenosis in internal carotid artery (ICA) and middle cerebral artery (MCA) (ICA-MCA)on MRA and cerebrovascular reserve (CVR) of MCA territory on SPECT was measured using quantification and a 3-grade system. Stenosis and CVR grades were compared with each other, and their prognost

Our environment is faced with serious problems related to the air pollution from automobiles in these days. In particular, the exhaust emissions from diesel engine are recognized main cause which influenced environment strong. In this study, the potential possibility of biodiesel fuel and oxygenates additives (dimethoxy methane) was investigated as an alternative fuel for a naturally aspirated direct injection diesel engine. The smoke emission of blending fuel (biodiesel fuel 90vol-% + DMM 10vol