백승환 교수

OBJECTIVES: We investigated the incidence and characteristics of cholangitis after Kasai portoenterostomy (KPE) in patients with biliary atresia. We also examined the distribution and antimicrobial susceptibility patterns of the causative pathogens, which were isolated in sterile specimens, such as blood and ascites. METHODS: A retrospective chart review was performed in patients with biliary atresia who underwent KPE at Severance Children's Hospital in Korea from 2006 to 2015. The Kaplan-Meier

BACKGROUND: Dexamethasone is widely used as a systemic corticosteroid to treat and prevent bronchopulmonary dysplasia (BPD) in preterm infants. We evaluated the current epidemiology of dexamethasone use to prevent BPD and analyse the factors associated with the response to dexamethasone in very low birthweight infants using a nationwide database. METHODS: We included very low birthweight infants born between January 2013 and December 2020 with a gestational age of 23-31 weeks using data from the

Antiviral initiation was delayed in RAT-false-negative patients. Our findings support the guideline that children with influenza, suspected of having severe or progressive infection, should be treated immediately.

Background: Management of hepatic hemangioma (HH) in infancy ranges from close monitoring to surgical resection. We analyzed the clinical characteristics and outcomes of HH according to its treatment options, with particular focus on challenging cases. Methods: Data of patients diagnosed with HHs in their first year of life and followed up for at least 1 year were retrospectively reviewed and divided into treatment and observation groups. Serial imaging results, serum alpha-fetoprotein (AFP) lev

Hemimegalencephaly (HME) is a rare disease characterized by partial or complete hypertrophy of one cerebral hemisphere.It is associated with intractable seizures, developmental delay, hemiparesis, and other neurological symptoms.Tuberous sclerosis (TSC) is a neurocutaneous syndrome that affects various organs, including the heart, brain, skin, kidney, and eyes, and is caused by mutations in TSC1 and TSC2 genes.Herein, we report the case of a patient with TSC and HME who required early neurosurgi

Chordomas originate from remnants of the embryonic notochord and account for < 2% of all malignant bone tumors (1). Although chordomas are low-grade tumors, they have a high rate of local recurrence, which makes clinical manifestation of a chordoma similar to a malignant tumor (2). In most cases, the initial clinical manifestations of a chordoma are neurological deficits caused by direct local invasion or the mass effect on adjacent structures (3). The incidence of chordoma metastasis varies wid

Gaucher disease (GD) is a rare autosomal recessive genetic disease. The symptoms and age of onset vary depending on the subtype. Type 2 GD is potentially lethal, and the mean lifespan is less than 2 years. Due to rapid disease progression, early diagnosis of type 2 GD is important. Here, we present an infant with congenital ichthyosis and rigidity with joint contracture, who later presented with bulbar involvement. Feeding difficulty, apnea, hepatosplenomegaly, and thrombocytopenia were also evi

Larger initial ventricle size in antenatal VM was associated with poorer neurodevelopmental outcomes. Normal antenatal findings can obscure postnatal CNS abnormalities. Advanced imaging and postnatal evaluation are essential for timely diagnosis and perinatal counseling and management.

Background: Neonatal morbidities are major determinants of clinical outcomes and healthcare utilization in preterm infants. However, population-level evidence quantifying the cumulative contribution of neonatal morbidities to neonatal intensive care unit (NICU) length of stay (LOS) and medical costs remains limited. Methods: We conducted a nationwide retrospective cohort study using the Korean Health Insurance Review and Assessment Service database. Preterm infants admitted to NICUs between 2020