Skip to main content

최승혜 교수

Seung-Hye Choi

연세대학교 의생명과학부 · 의학

연구실 소개

최승혜 교수의 연구실은 주로 식품과 장내 미생물, 만성 질환 간의 상호작용을 중심으로 한 기능성 식품의 질병 예방 및 치료 기전을 연구하고 있습니다. 특히 김치의 항염증, 항암, 근육분해 억제 작용 등에 기반한 암 케이크시아, 위암, 뇌졸중 후 통증 등 만성질환의 예방 및 관리 전략을 개발하고 있습니다. 장내 미생물 조절을 통한 면역 조절 및 체내 염증 반응 조절 메커니즘을 중심으로 기초 및 번역 연구를 병행하고 있습니다.

김치장내 미생물암 케이크시아염증 조절기능성 식품

연구 현황

논문 수
36
총 인용 수
299
최근 5년 논문
8
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
8총합
2019
2020
2021
2022
2023
5개년 연도별 피인용 수
92총합
20192020202120222023

주요 논문

15
1
논문|인용수 55·2016
Musculoskeletal and central pain at 1 year post-stroke: associated factors and impact on quality of life
Smi Choi‐Kwon, Seung Hye Choi, Minhee Suh, Se Hyun Choi, Kyung‐Hee Cho, Hyun Wook Nah, Ha-Sup Song, J. S. Kim
SJR Q1Acta Neurologica Scandinavica

Pain is common 12 months post-stroke. The factors associated with CPSP and MSP differ, but are both closely associated with fatigue rather than depression. QOL is the poorest in patients with combined pain. Management of pain and fatigue may be important for improving the QOL in stroke patients.

RehabilitationMedicine
2
리뷰|인용수 44·2004
Malignant Gastrointestinal Stromal Tumor of the Gallbladder
Jong Kyung Park, Seung Hye Choi, Seong Lee, Ki Ouk Min, Sang Seob Yun, Hae Myung Jeon
SJR Q2Journal of Korean Medical ScienceOA

Gastrointestinal stromal tumors (GISTs) of the gallbladder are representative of an extremely rare group of tumors. We have encountered a patient with a malignant GIST of the gallbladder and presented it with a review of some articles. A 72-yr-old woman initially presented with right upper quadrant abdominal pain, fever and chills. Emergency cholecystectomy was performed under the impression of gallbladder empyema. Liver metastasis was found at 7 months postoperatively and the patient expired 9

GastroenterologyMedicine
3
논문|인용수 38·2013
Synbiotic impact of tagatose on viability of Lactobacillus rhamnosus strain GG mediated by the phosphotransferase system (PTS)
Ji Hoon Koh, Seung Hye Choi, Seung Won Park, Nag-Jin Choi, Younghoon Kim, Sae Hun Kim
SJR Q1Food Microbiology
Endocrinology, Diabetes and MetabolismMedicine
4
논문|인용수 33·2019
Dietary intake of probiotic kimchi ameliorated IL-6-driven cancer cachexia
Jeong Min An, Eun Ae Kang, Young‐Min Han, Ji Young Oh, Dong Yoon Lee, Seung Hye Choi, Duk Hwan Kim, Ki Baik Hahm
SJR Q2Journal of Clinical Biochemistry and NutritionOA

Cancer cachexia is a syndrome accompanying weight loss, skeletal muscle atrophy, and loss of adipose tissue in patients with advanced cancer. Since interleukin-6 (IL-6) is one of core mediators causing cancer cachexia and kimchi can modulate IL-6 response, we hypothesized dietary intake of kimchi can ameliorate cancer cachexia. In this study, we studied preemptive administration of kimchi can ameliorate mouse colon carcinoma cells colon (C26) adenocarcinoma-induced cancer cachexia and explored a

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
논문|인용수 30·2015
Factors Affecting Nursing Students' Practice of Patient Safety Management in Clinical Practicum
Seung Hye Choi, Haeyoung Lee
SJR Q2Journal of Korean Academy of Nursing AdministrationOA

Purpose: This study was done to assess nursing students’ practice of patient safety management (PSM), identify factors affecting PSM and provide basic data to develop education programs to strengthen students’ competencies for patient safety. Methods: In this descriptive research the practice of PSM by nursing students was examined and predictive factors were identified. Participants were junior and senior nursing students from 7 universities in 7 cities. Self-report questionnaires were used for

PharmacyHealth Professions
6
논문|인용수 29·2020
Dietary intake of fermented kimchi prevented colitis-associated cancer
Young‐Min Han, Eun Ae Kang, Jong Min Park, Ji Young Oh, Dong Yoon Lee, Seung Hye Choi, Ki Baik Hahm
SJR Q2Journal of Clinical Biochemistry and NutritionOA

Kimchi is composed of various chemopreventive phytochemicals and profuse probiotics, defining kimchi as probiotic foods. Concerns had increased on the modulation of intestinal microbiota on various kinds of systemic diseases. Under the hypothesis that dietary intake of kimchi can be ideal intervention for either ameliorating colitis or preventing colitic cancer, we performed the study to validate the efficolitic cancery of fermented kimchi on preventing colitic cancer. Using azoxymethane-initiat

Food ScienceAgricultural and Biological Sciences
7
논문|인용수 13·2021
Fermented kimchi rejuvenated precancerous atrophic gastritis via mitigating <i>Helicobacter pylori</i>-associated endoplasmic reticulum and oxidative stress
Jong Min Park, Young Min Han, Ji Young Oh, Dong Yoon Lee, Seung Hye Choi, Seong-Jin Kim, Ki Baik Hahm
SJR Q2Journal of Clinical Biochemistry and NutritionOA

Dietary intervention to prevent <i>Helicobacter pylori</i> (<i>H. pylori</i>)-gastric cancer might be ideal by long-term intervention, rejuvenating action, and no risk of bacterial resistance. Stimulated with finding that kimchi prevented <i>H. pylori</i>-gastric cancer, we compared the efficacy of cancer preventive kimchi (cpkimchi) and standard recipe kimchi (skimchi) and the efficacy between fermented kimchi and non-fermented kimchi (kimuchi) in <i>H. pylori</i>-initiated gastric cancer model

SurgeryMedicine
8
논문|인용수 11·2009
Malignant Peripheral Nerve Sheath Tumor of the Breast in a Patient without Neurofibromatosis: A Case Report
Jeong Min Yi, Eun Jeong Moon, Se Jeong Oh, Ahni Lee, Young Jin Suh, Jong Min Baek, Seung Hye Choi, Sang Seol Jung
SJR Q2Journal of Breast CancerOA

Malignant peripheral nerve sheath tumors (MPNSTs) are malignant variants of peripheral nerve sheath tumors that develop at major or minor peripheral nerve branches or at the sheaths of peripheral nerve fibers. These tumors are derived from Schwann cells or pluripotent cells of a neural crest origin. Malignant tumors of the peripheral nerve sheath are most commonly seen in deeper soft tissues, and usually in the proximity of a nerve trunk. MPNSTs of the breast are very uncommon and they have rare

NeurologyMedicine
9
논문|인용수 8·2022
The different prognostic impact of age according to individual molecular subtypes in breast cancer
Nam Hee Kim, Hye Won Bang, Yong Hwa Eom, Seung Hye Choi
SJR Q2Annals of Surgical Treatment and ResearchOA

Purpose: Young age at diagnosis has been considered a poor prognostic factor. However, considering young age itself as an independent poor prognostic factor for all breast cancers is unwarranted. We analyzed the different prognostic effects of age as a prognostic factor according to molecular subtype. Methods: We retrieved data from 1,819 patients with primary breast cancer at the breast cancer center between 2007 and 2012. We classified each molecular subtype in 3 age cohorts (<40, 40-50, and >

Cancer ResearchBiochemistry, Genetics and Molecular Biology
10
논문|인용수 7·2015
Trend Analysis of Research in the Korean Journal of Adult Nursing for 5 Years (2010~2014): Focused on Usage of Nursing Theories
Nam Kyung Han, Sanghee Kim, Myoung Shin Kim, Jong Gun Kim, Chang Hwan Kim, Seung Hye Choi
SJR Q3Korean Journal of Adult NursingOA

Purpose: The purpose of this study was to analyze the trend of nursing theories by Korean Journal of Adult Nursing (KJAN) for the last five years and to provide future directions for improvement. \n\nMethods: The study analyzed data collected from 323 research papers published in KJAN between 2010~2014. Descriptive analysis was conducted with a focus on frequency and percentage for the quantitative analysis. Qualitative analysis was performed for the analysis of nursing theories. \n\nResults: As

Public Health, Environmental and Occupational HealthMedicine
11
논문|인용수 6·1999
A Case of Primary Leiomyosarcoma of the Lesser Omentum
Don Hyoun Joe, Jin Mo Yang, Hyun Su Kim, Sung Soo Kim, Sang Wook Choi, Seung Hye Choi, Seong Lee, Keun Woo Lim
SJR Q2The Korean Journal of Internal MedicineOA

Leiomyosarcoma is a rare tumor that originates in the smooth muscle, usually in the gastrointestinal tract, the retroperitoneum and the genitourinary tract. The omentum has been rarely reported as a primary site of occurrence with leiomyosarcoma. A 72 year-old woman, with palpable mass on the left upper quadrant of abdomen and weight loss, was admitted to St. Paul's Hospital. Abdominal CT scan showed a 12 x 8 x 8 cm-sized cystic mass in the left upper quadrant of the abdomen. Endoscopic ultrason

GastroenterologyMedicine
12
논문|인용수 5·2015
Granular Cell Tumor of the Thyroid Gland: A Case Report and Review of the Literature
Woo Chan Park, Seung Hye Choi, Youn Soo Lee
The Korean Journal of Endocrine SurgeryOA
Pathology and Forensic MedicineMedicine
13
논문|인용수 5·2021
Transcriptome profiling implicated in beneficiary actions of kimchi extracts against <i>Helicobacter pylori</i> infection
Jong Min Park, Young Min Han, Ji Young Oh, Dong Yoon Lee, Seung Hye Choi, Ki Baik Hahm
SJR Q2Journal of Clinical Biochemistry and NutritionOA

Dietary intervention to prevent <i>Helicobacter pylori</i> (<i>H. pylori</i>)-gastric cancer might be ideal because of no risk of bacterial resistance, safety, and rejuvenating action of atrophic gastritis. We have published data about the potential of fermented kimchi as nutritional approach for <i>H. pylori</i>. Hence recent advances in RNAseq analysis lead us to investigate the transcriptome analysis to explain these beneficiary actions of kimchi. gastric cells were infected with either <i>H.

SurgeryMedicine
14
논문|인용수 3·2021
Eosinophilic Mastitis: A Case Report
Hye Won Bang, Kwan Ho Lee, Hyeon Sook Kim, Ki Ouk Min, Seung Hye Choi
Journal of Breast DiseaseOA

Eosinophilic mastitis is a rare disease in which eosinophils infiltrate the ducts and lobules of the breast, causing mammary inflammation. Although eosinophilic mastitis is a benign condition, it presents similarly to and is often mistaken for breast cancer. Here we report the first case of eosinophilic mastitis in Korea. A 43-year-old woman presented with redness and swelling in her right breast. A breast ultrasound revealed ill-defined isoechoic and hyperechoic areas in the upper half and lowe

RheumatologyMedicine
15
리뷰|인용수 1·2008
A Review of the Classification of the Practice Characteristics andthe Physicians' Work in Vascular Surgery
Seung Hye Choi, Sang Seob Yun
Daehan hyeolgwan oe'gwa haghoeji
SurgeryMedicine

대표 연구 분야

SurgeryGeneticsPathology and Forensic MedicinePulmonary and Respiratory MedicineGastroenterologyMolecular Biology

최승혜 교수의 연구를 Nubint에서 더 깊이 살펴보세요

이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.