이승로 교수
Seung Ro Lee
한양대학교 영상의학과 · 의학
연구실 소개
이승로 교수의 연구실은 신경영상의학과 생체영상 기반의 뇌질환 및 뇌손상 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 특히 뇌경색에서의 세포사 조절 기전과 신경보호 작용을 연구하며, 이는 파라티로이드 폴리메라제(PARP) 억제제의 작용 기전을 밝혀내는 데 기여하고 있습니다. 또한, 금속 forming 공정에서의 에너지 소비 예측과 프리포밍 형상 설계에 머신러닝 기반의 혁신적 접근을 도입하여, 의료영상과 공정공학의 융합 연구를 선도하고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15A series of 210 patients with facial fractures sufficiently severe to require cranial computerized tomography (CT) to evaluate suspected closed-head injury (CHI) was studied. The injuries were separated into five grades of severity based on neurological examination, including cranial CT. The injuries were also grouped into three categories based on facial regional involvement, using chi-square contingency table analysis. The data demonstrated that patients with upper facial fractures were at gre
Multilocular thymic cysts typically manifest on CT as unilocular or multilocular cystic thymic masses, often with soft-tissue attenuation components. CT cannot be used to distinguish neoplastic from nonneoplastic soft-tissue components.
Poly(ADP-ribose) polymerase (PARP) plays an important role in ischaemic cell death, and 3-aminobenzamide (3-AB), one of the PARP inhibitors, has a protective effect on ischaemic stroke. We investigated the neuroprotective mechanisms of 3-AB in ischaemic stroke. The occlusion of middle cerebral artery (MCA) was made in 170 Sprague-Dawley rats, and reperfusion was performed 2 h after the occlusion. Another 10 Sprague-Dawley rats were used for sham operation. 3-AB was administered to 85 rats 10 min
Basal cell adenoma is a rare benign salivary gland epithelial tumor, usually involving the parotid gland. We report CT and MR findings of three cases with basal cell adenoma occurring in the parotid gland. The three cases presented here demonstrate a well-circumscribed tumor, which showed a cystic and solid, or the pure solid mass. They were well enhanced after contrast matter injection. The solid portion of the mass was isoattenuated at CT, with intermediate signal intensity on T1- and T2-weigh
This research provides an insight on the performances of machine learning (ML)-based algorithms for the estimation of the energy consumption in metal forming processes and is applied to the radial-axial ring rolling process. To define the mutual influence between ring geometry, process settings, and ring rolling mill geometries with the resulting energy consumption, measured in terms of the force integral over the processing time (FIOT), FEM simulations have been implemented in the commercial SW
This study presents an innovative methodology for preform design in metal forging processes based on the convolution neural network (CNN) algorithm. The proposed approach extracts the features of inputted forging product geometries and utilizes them to derive the corresponding preform shapes by employing weight arrays (filters) determined during the convolutional operations. The filters are progressively updated during the training process, emulating the learning steps of a process engineer resp
Ankylosing spondylitis (AS) results in disease-specific inflammation at the site of ligamentous insertion into the bone. Atlantoaxial joint subluxation and vertical subluxation of the axis may occur as a consequence of instability resulting from the inflammatory process. Spontaneous anterior atlantoaxial subluxation is a well recognized complication in about 2% of patients with AS, and presents with or without signs of spinal cord compression. Vertical subluxation may follow anterior or posterio
We report a case of hypereosinophilia causing multiple areas of cerebral infarcts. A 52-year-old Korean man presented with dysarthria and weakness in both arms. A brain MRI revealed multiple acute infarcts in the distal border zone with focal intracerebral hemorrhage, whereas a cerebral angiogram was not remarkable. The eosinophil count was 5,500/microL and was accompanied by elevated cardiac enzyme levels. The pattern of cerebral infarcts and laboratory results suggest a thromboembolic infarcti
Sheets’ buckling instability, also known as oil canning, is an issue that characterizes the resistance to denting in thin metal panels. The oil canning phenomenon is characterized by a depression in the metal sheet, caused by a local buckling, which is a critical design issue for aesthetic parts, such as automotive outer panels. Predicting the buckling instability during the design stage is not straightforward since the shape of the component might change several times before the part is sent to
Loss of knee cartilage can cause intense pain at the knee epiphysis and this is one of the most common diseases worldwide. To diagnose this condition, the distance between the femur and tibia is calculated based on X-ray images. Accurate segmentation of the femur and tibia is required to assist in the calculation process. Several studies have investigated the use of automatic knee segmentation to assist in the calculation process, but the results are of limited value owing to the complexity of t
Most intrasellar meningiomas are located in the subdiaphragmatic and supraglandular region because they originate from the diaphragma sellae. Subglandular meningiomas located under the pituitary gland are extremely rare. Intrasellar meningiomas in the subdiaphragmatic and subglandular region probably originate from the dura in the sellar floor. We report a case of a subglandular meningioma along with a review of the literature.
Purpose: To evaluate post-ablation syndrome after radiofrequency thermal ablation of malignant hepatic tumors. Materials and Methods: Forty-two patients with primary (n=29) or secondary (n=13) hepatic tumors under-went radiofrequency thermal ablation. A total of 65 nodules ranging in size from 1.1 to 5.0 (mean, 3.1) cm were treated percutaneously using a 50W RF generator with 15G expandable needle electrodes. We retrospec-tively evaluated the spectrum of post-ablation syndrome including pain, fe
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