김승한 교수
Seunghan Kim
고려대학교 내과 · 의학
연구실 소개
김승한 교수의 연구실은 소화기계 질환의 비침습적 진단 및 치료 기술 개발에 초점을 맞추고 있습니다. 특히 내 endoscopic 치료법, 예를 들어 위장관 내 배치 가능한 복강내 볼루스(내시경 비만치료)와 혈관내 내시경 캡슐 엔도스코피 기술의 임상적 응용을 연구하고 있습니다. 또한 항암치료 유발 장내 염증(장점막염)의 예방 및 치료를 위한 약리학적 전략, 특히 유르소디옥시콜린산의 세포보호 작용에 대한 기전 연구도 진행 중입니다. 이는 환자의 삶의 질 향상과 합병증 감소에 기여할 잠재력을 지닌 분야입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Endoscopic bariatric therapy may be a useful alternative to pharmacological treatment for obesity, and it provides greater efficacy with lower risks than do conventional surgical procedures. Among the various endoscopic treatments for obesity, the intragastric balloon is associated with significant efficacy in body weight reduction and relief of comorbid disease symptoms. Anatomically, this treatment is based on gastric space-occupying effects that increase the feeling of satiety and may also af
The purpose of the course presented here is to introduce freshmen to embedded systems using LEGO Mindstorms, under an ANSI-C programming environment. The students build their own LEGO robots, make programs for them using ANSI-C, and operate them. By creating these LEGO robots, the students become more motivated, learning the basic concepts of embedded systems and how these concepts can be applied to real world problems.
BACKGROUND: Tegoprazan is a novel, fast- and long-acting potassium-competitive acid blocker that suppresses gastric acid secretion, which could benefit patients with non-erosive reflux disease (NERD), a type of gastroesophageal reflux disease. AIM: To evaluate the efficacy and safety profiles of tegoprazan compared with those of a placebo in Korean patients with NERD. METHODS: In this phase 3, double-blind, placebo-controlled, multicentre study, 324 Korean patients with NERD were randomised into
Lego Company has made a programmable robot set named Mindstorms NXT(NXT). This set comes with several types of sensors, motor, and programmable brick. The NXT set is provided with visual programming environment. Novice programmer can easily make a program for robot using this visual programming environment. The software of NXT is based on National Instruments’ LabVIEW. Also, Microsoft developed a platform called Microsoft Robotics Studio(MSRS) which is aimed to support all types of robot. MSRS a
Capsule endoscopy of the gastrointestinal tract is an innovative technology that serves to replace conventional endoscopy. Wireless capsule endoscopy, which is mainly used for small bowel examination, has recently been used to examine the entire gastrointestinal tract. This method is promising for its usefulness and development potential and enhances convenience by reducing the side effects and discomfort that may occur during conventional endoscopy. However, capsule endoscopy has fundamental li
Intestinal mucositis is a commonly encountered complication of chemotherapy. However, there are few effective treatments or preventive methods. Ursodeoxycholic acid (UDCA) stabilizes cell membranes, acts as an antioxidant and inhibits apoptosis, thereby exerting cytoprotective effects. The aim of the present study was to examine the ability of UDCA to protecting against chemotherapy-associated mucositis. Sprague-Dawley rats were randomly assigned to five groups: Control, vehicle + 5-fluorouracil
BACKGROUND AND STUDY AIMS: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in patients with overt obscure gastrointestinal bleeding (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. PATIENTS AND METHODS: We retrospectively enrolled patients who ha
A robot highly motivates students and it is one of the best ways to connect students with the technology. LEGO created a set called robotic invention system. This system helps students to understand the technology of both robot and programming language. It also improves creativeness by building and controlling the robot. This paper would propose the idea on educating C language to students using Robotic Invention System 2.0
We recommend using etomidate-midazolam in patients with high ASA score or vulnerable to risk factors; propofol-midazolam may be used as a guideline in patients with low ASA score.
GES is feasible with our minimally invasive wireless device. This technique has the potential to increase utilization of GES as a treatment alternative.
Background/Aims . Capsule endoscopy (CE) is a noninvasive test for diagnosing small bowel disorders. However, several studies reported that the CE-based visualization is suboptimal. This study, the first to use two CEs simultaneously, aimed at evaluating the diagnostic ability of dual CE. Methods . Dual CE procedures were prospectively conducted. All patients completed bowel cleansing 2 hours before examination. Subsequently, they simultaneously swallowed two capsules: MiroCam (IntroMedic, Seoul
Among variously sized resected tissue specimens, submucosal thicknesses were more variable in the conventional fixation group, while the thicknesses were comparatively consistent in the fixation device group. After endoscopic submucosal dissection, pathologic preparation using this fixation device could offer more objective assessment of specimens.
The safety of bowel-cleansing agents is an important issue in clinical practice, especially in patients with chronic diseases. Although the safety and efficacy of polyethylene glycol (PEG) has been investigated in many studies, few studies on PEG plus ascorbic acid exist. In this study, we compared the safety of 2 bowel-cleansing agents for patients with liver cirrhosis: 2-liter PEG (2 L PEG) plus ascorbic acid versus 4-liter PEG (4 L PEG). We performed a retrospective study on colonoscopy in pa
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