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이소희 교수

So Hee Lee

서울대학교 내과 · 의학

연구실 소개

이소희 교수의 연구실은 천식 및 만성 호흡기질환의 조절 수준과 환자의 삶의 질 간의 관계를 밝히는 데 초점을 맞추고 있으며, 특히 한국어로 번역된 천식 조절 검사(Act)와 질환 관련 삶의 질(AQLQ) 측정 도구의 신뢰성과 타당성을 검증하는 데 기여하고 있습니다. 또한 알츠하이머병과 같은 신경퇴행성 질환에서 장내 미생물과 뇌 간의 상호작용을 탐구하며, 한국홍삼(KRG)이 장-뇌 축을 통해 뇌 기능에 미치는 영향을 생물학적 모델을 통해 규명하고 있습니다. 추가로, 자기공명영상(MRI)의 정확도를 높이기 위한 다중구역 구조의 병리 모의체 개발을 통해 의료 영상 기술의 표준화에도 기여하고 있습니다.

천식 조절장-뇌 축장내 미생물의료 영상 표준화한국홍삼

연구 현황

논문 수
52
총 인용 수
630
최근 5년 논문
11
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
11총합
2020
2021
2022
2023
2025
5개년 연도별 피인용 수
73총합
20202021202220232025

주요 논문

15
1
논문|인용수 140·2008
Epidemiologic and clinical features of anaphylaxis in Korea
Min‐Suk Yang, So-Hee Lee, Tae‐Wan Kim, Jae‐Woo Kwon, Sang Min Lee, Sae‐Hoon Kim, Hyouk-Soo Kwon, Changhan Park, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung‐Up Min
SJR Q1Annals of Allergy Asthma & Immunology
Immunology and AllergyMedicine
2
논문|인용수 55·2008
Correlation between the Korean Version of Asthma Control Test and Health-Related Quality of Life in Adult Asthmatics
Hyouk‐Soo Kwon, So-Hee Lee, Min‐Suk Yang, Sang Min Lee, Sae‐Hoon Kim, Deok-In Kim, Seong-Wook Sohn, Chang-Han Park, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung-Up Min
SJR Q2Journal of Korean Medical ScienceOA

The Asthma Control Test (ACT) is a patient-completed questionnaire developed to assess asthma control. Health-related quality of life (HRQL) in asthmatics has shown relatively low correlations with parameters of asthma control and the relationship between the ACT and HRQL in asthmatics is yet unclear. Because revalidations of translated versions of questionnaires are critical for its utilization, we first sought to validate the Korean version of ACT and then to evaluate the relationship between

PhysiologyMedicine
3
논문|인용수 48·2010
Outcomes of premedication for non-ionic radio-contrast media hypersensitivity reactions in Korea
Sae‐Hoon Kim, So-Hee Lee, Sang Min Lee, Hye‐Ryun Kang, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung-Up Min, You-Young Kim, Yoon‐Seok Chang
SJR Q1European Journal of Radiology
Immunology and AllergyMedicine
4
논문|인용수 31·2014
Are asthmatic patients prone to bone loss?
Jae-Woo Jung, Hye‐Ryun Kang, Ju‐Young Kim, So-Hee Lee, Sun-Sin Kim, Sang‐Heon Cho
SJR Q1Annals of Allergy Asthma & Immunology
Pathology and Forensic MedicineMedicine
5
논문|인용수 29·2010
Toll-like Receptor Expression on Peripheral Blood Mononuclear Cells in Asthmatics; Implications for Asthma Management
Eunyoung Chun, So-Hee Lee, Soo‐Yeon Lee, Eun-Jin Shim, Sang‐Heon Cho, Kyung‐Up Min, You-Young Kim, Heung‐Woo Park
SJR Q1Journal of Clinical Immunology
PhysiologyMedicine
6
논문|인용수 28·2010
Dexamethasone-Induced FKBP51 Expression in Peripheral Blood Mononuclear Cells Could Play a Role in Predicting the Response of Asthmatics to Treatment with Corticosteroids
Eunyoung Chun, Hyun Seung Lee, Bo‐Ram Bang, Tae‐Wan Kim, So-Hee Lee, Ju Han Kim, Sang‐Heon Cho, Kyung-Up Min, You-Young Kim, Heung‐Woo Park
SJR Q1Journal of Clinical Immunology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 24·2021
Effect of Lactobacillus dominance modified by Korean Red Ginseng on the improvement of Alzheimer's disease in mice
Mijung Lee, So-Hee Lee, Min‐Soo Kim, Min‐Soo Kim, Kwang‐Sung Ahn, Manho Kim, Manho Kim
SJR Q1Journal of Ginseng ResearchOA

Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divid

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 22·2014
The Interaction Between Allelic Variants ofCD86andCD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis
So-Hee Lee, Eun-Bong Lee, Eun‐Soon Shin, Jong Eun Lee, Sang‐Heon Cho, Kyung-Up Min, Heung‐Woo Park
SJR Q1Allergy Asthma and Immunology ResearchOA

Our findings suggest that a genetic interaction between CD86 and CD40LG favors the development of both AA and RA.

PhysiologyMedicine
9
논문|인용수 20·2014
Influence of Chronic Sinusitis and Nasal Polyp on the Lower Airway of Subjects Without Lower Airway Diseases
Suh‐Young Lee, Soon Ho Yoon, Woo‐Jung Song, So-Hee Lee, Hye‐Ryun Kang, Sun-Sin Kim, Sang‐Heon Cho
SJR Q1Allergy Asthma and Immunology ResearchOA

CT findings suggesting chronic sinusitis and nasal polyp were associated with subclinical lower airway flow limitation even in the absence of underlying lung disease.

OtorhinolaryngologyMedicine
10
논문|인용수 18·2013
New insight into the assessment of asthma using xenon ventilation computed tomography
Jae‐Woo Jung, Jae‐Woo Kwon, Tae‐Wan Kim, So-Hee Lee, Kyung-Mook Kim, Hye‐Ryun Kang, Heung‐Woo Park, Chang Hyun Lee, Jin-Mo Goo, Kyung‐Up Min, Sang‐Heon Cho
SJR Q1Annals of Allergy Asthma & Immunology
Atomic and Molecular Physics, and OpticsPhysics and Astronomy
11
논문|인용수 18·2010
The effects of PG102, a water-soluble extract from Actinidia arguta, on serum total IgE levels: a double-blind, randomized, placebo-controlled exploratory clinical study
Sae‐Hoon Kim, Sunyoung Kim, So-Hee Lee, Heung‐Woo Park, Yoon‐Seok Chang, Kyung-Up Min, Sang‐Heon Cho
SJR Q1European Journal of Nutrition
PhysiologyMedicine
12
논문|인용수 16·2019
Fabrication of a spherical inclusion phantom for validation of magnetic resonance-based magnetic susceptibility imaging
Jun‐Ho Kim, Jung‐Hyun Kim, So-Hee Lee, So-Hee Lee, Jinhyoung Park, Seung‐Kyun Lee, Seung‐Kyun Lee
SJR Q1PLoS ONEOA

Fabrication of a spherical multi-compartment MRI phantom is demonstrated that can be used to validate magnetic resonance (MR)-based susceptibility imaging reconstruction. The phantom consists of a 10 cm diameter gelatin sphere that encloses multiple smaller gelatin spheres doped with different concentrations of paramagnetic contrast agents. Compared to previous multi-compartment phantoms with cylindrical geometry, the phantom provides the following benefits: (1) no compartmental barrier material

Radiology, Nuclear Medicine and ImagingMedicine
13
논문|인용수 15·2015
Validation of the Korean version of the European Community Respiratory Health Survey screening questionnaire for use in epidemiologic studies for adult asthma
Woo‐Jung Song, So-Hee Lee, Min‐Gyu Kang, Ju‐Young Kim, Miyoung Kim, Eun‐Jung Jo, Suh‐Young Lee, Seung Eun Lee, Min‐Hye Kim, Min‐Suk Yang, Sae‐Hoon Kim, Hye‐Ryun Kang
SJR Q2Asia Pacific AllergyOA

The present study demonstrated that the Korean version of the ECRHS screening questionnaire was comprehensible, reliable and valid. We suggest the questionnaire to be utilized in further epidemiological studies for asthma in Korean adult populations.

PhysiologyMedicine
14
논문|인용수 14·2015
Reliability and Validity of a Korean Version of the Leicester Cough Questionnaire
권재우, 문지용, 김세훈, 송우정, 김민혜, 강민규, 임경환, 이소희, 이상민, 이진영, 권혁수, 김경묵

Purpose: There are no specific tools for measurement of the severity of chronic cough in Korea. We developed a Korean version of the Leicester Cough Questionnaire (LCQ) and tested its scaling and clinical properties. Methods: The LCQ was adapted for Korean conditions following a forward- backward translation procedure. All patients referred to chronic cough clinics at 5 university hospitals between May 2011 and October 2013 completed 2 questionnaires, the LCQ and the Short-Form 36 (SF-36), upon

15
논문|인용수 14·2020
Blood Eosinophil Count as a Predictor of Lung Function Decline in Healthy Individuals
So-Hee Lee, Kyung‐Min Ahn, Suh‐Young Lee, Sun-Sin Kim, Heung‐Woo Park
SJR Q1The Journal of Allergy and Clinical Immunology In Practice
PhysiologyMedicine

대표 연구 분야

PhysiologyImmunology and AllergyPharmacologyPathology and Forensic MedicineMolecular BiologyRenewable Energy, Sustainability and the Environment

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