이소희 교수
So Hee Lee
서울대학교 내과 · 의학
연구실 소개
이소희 교수의 연구실은 천식 및 만성 호흡기질환의 조절 수준과 환자의 삶의 질 간의 관계를 밝히는 데 초점을 맞추고 있으며, 특히 한국어로 번역된 천식 조절 검사(Act)와 질환 관련 삶의 질(AQLQ) 측정 도구의 신뢰성과 타당성을 검증하는 데 기여하고 있습니다. 또한 알츠하이머병과 같은 신경퇴행성 질환에서 장내 미생물과 뇌 간의 상호작용을 탐구하며, 한국홍삼(KRG)이 장-뇌 축을 통해 뇌 기능에 미치는 영향을 생물학적 모델을 통해 규명하고 있습니다. 추가로, 자기공명영상(MRI)의 정확도를 높이기 위한 다중구역 구조의 병리 모의체 개발을 통해 의료 영상 기술의 표준화에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The Asthma Control Test (ACT) is a patient-completed questionnaire developed to assess asthma control. Health-related quality of life (HRQL) in asthmatics has shown relatively low correlations with parameters of asthma control and the relationship between the ACT and HRQL in asthmatics is yet unclear. Because revalidations of translated versions of questionnaires are critical for its utilization, we first sought to validate the Korean version of ACT and then to evaluate the relationship between
Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divid
Our findings suggest that a genetic interaction between CD86 and CD40LG favors the development of both AA and RA.
CT findings suggesting chronic sinusitis and nasal polyp were associated with subclinical lower airway flow limitation even in the absence of underlying lung disease.
Fabrication of a spherical multi-compartment MRI phantom is demonstrated that can be used to validate magnetic resonance (MR)-based susceptibility imaging reconstruction. The phantom consists of a 10 cm diameter gelatin sphere that encloses multiple smaller gelatin spheres doped with different concentrations of paramagnetic contrast agents. Compared to previous multi-compartment phantoms with cylindrical geometry, the phantom provides the following benefits: (1) no compartmental barrier material
The present study demonstrated that the Korean version of the ECRHS screening questionnaire was comprehensible, reliable and valid. We suggest the questionnaire to be utilized in further epidemiological studies for asthma in Korean adult populations.
Purpose: There are no specific tools for measurement of the severity of chronic cough in Korea. We developed a Korean version of the Leicester Cough Questionnaire (LCQ) and tested its scaling and clinical properties. Methods: The LCQ was adapted for Korean conditions following a forward- backward translation procedure. All patients referred to chronic cough clinics at 5 university hospitals between May 2011 and October 2013 completed 2 questionnaires, the LCQ and the Short-Form 36 (SF-36), upon
대표 연구 분야
이소희 교수의 연구를 Nubint에서 더 깊이 살펴보세요
이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.