박소연 교수

Staphylococcus aureus is a formidable bacterial pathogen that is responsible for infections in humans and various species of wild, companion, and agricultural animals. The ability of S. aureus to move between humans and livestock is due to specific characteristics of this bacterium as well as modern agricultural practices.

This study aimed to compare the mean scores of mobile phone use, mobile phone addiction, and depressive symptoms at three-time points among Korean adolescents according to gender and to examine the differences in the long-term relationships among the three abovementioned variables between Korean boys and girls in a four-year period. Data for 1794 adolescents (897 boys and 897 girls) were obtained from three waves of the second panel of the Korean Children and Youth Panel Survey. Multigroup struc

BACKGROUND: Pseudomonas aeruginosa has gained an increasing amount of attention in the treatment of patients with pneumonia. However, the benefit of empirical combination therapy for pneumonia remains unclear. We evaluated the effects of adequate empirical combination therapy and multidrug-resistance in bacteremic Pseudomonas pneumonia on the mortality. METHODS: A retrospective cohort study was performed at the 2,700-bed tertiary care university hospital. We reviewed the medical records of patie

Few antiviral agents are available for treating paramyxovirus infections, such as those involving respiratory syncytial virus (RSV), parainfluenza virus (PIV), and human metapneumovirus (hMPV). We evaluated the effect of oral ribavirin on clinical outcomes of paramyxovirus infections in patients with hematological diseases. All adult patients with paramyxovirus were retrospectively reviewed over a 2-year period. Patients who received oral ribavirin were compared to those who received supportive

In South Korea, 4.5% patients of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were readmitted to hospitals after discharge. However, there is insufficient research on risk factors for readmission and management of patients after discharge is poor. In this study, 7590 confirmed coronavirus disease (COVID-19) patients were defined as a target for analysis using nationwide medical claims data. The demographic characteristics, underlying diseases, and the use of medical resources wer

PURPOSE: This cross-sectional study investigated the status of life-sustaining treatment (LST) practices and identified characteristics and factors influencing decision-making practices. MATERIALS AND METHODS: The National Agency for Management of Life-sustaining Treatment retains records provided by doctors regarding patients subject to LST implementation. A total of 71,327 patients receiving LST were identified. We analyzed all nationally reported data between February 2018 and October 2019. I

Hypertension affects about one in three US adults, from recent surveillance, or four in nine based on the 2017 ACC/AHA Hypertension Guideline; about half of them have their blood pressure controlled, and nearly one in six are unaware of their hypertension status. National estimates of hypertension awareness, treatment, and control in the United States are traditionally based on measured BP from National Health and Nutrition Examination Survey (NHANES); however, at the state level, only self-repo

Staphylococcus aureus is a major etiological agent of clinical and subclinical bovine mastitis. The versatile and adaptative evolutionary strategies of this bacterium have challenged mastitis control and prevention globally, and the high incidence of S. aureus mastitis increases concerns about antimicrobial resistance (AMR) and zoonosis. This study aims to describe the evolutionary relationship between bovine intramammary infection (IMI)-associated S. aureus and human pathogenic S. aureus and fu

본 연구는 제5차 청소년건강행태 온라인조사 자료를 활용해 청소년의 인터넷 중독에 영향을 미치는 요인을 인구사회학적 특성 요인, 건강 요인, 일탈행동 요인을 중심으로 탐색하였다. 이를 위해 본 연구에서는 첫째, 독립변인인 인구사회학적 특성 요인, 건강 요인, 일탈행동 요인과 종속변인인 인터넷 중독 수준을 빈도분석, 백분율, 평균 등의 기술 통계분석을 통해 파악하였으며, 둘째, 각 독립변인의 하위집단별 인터넷 중독 수준의 차이를 카이자승 검증을 통해 비교분석하였으며, 셋째, 각 독립변인들이 인터넷 중독에 미치는 영향을 로지스틱회귀분석을 통해 파악하였다. 연구결과를 로지스틱 회귀분석에 의해 제시하면, 인구사회학적 특성 요인에서는 남학생인 경우에, 양부모와 동거하지 않는 경우에, 가계의 경제수준이 낮은 경우에, 학업성적이 낮은 경우에, 건강 요인에 있어서는 주관적으로 건강하지 못하다고 느끼는 경우에, 주관적으로 행복하지 못하다고 느끼는 경우에, 스트레스정도가 높은 경우에, 우울을 경험한 경

OBJECTIVES: We performed a prospective observational study comparing the efficacy and safety of low-dose ganciclovir (5 mg/kg/day) as initial preemptive therapy in allogeneic haematopoietic stem cell transplantation (HSCT) recipients with conventional-dose ganciclovir (10 mg/kg/day). METHODS: All adult patients undergoing allogeneic HSCT were enrolled at a transplant centre over a 24 month period. The decision to use low-dose or conventional-dose ganciclovir was at the discretion of each attendi

Esterases represent a large family of hydrolases with broad substrate specificity and functional sequence space. Although many attempts to screen new esterases have been conducted, there have been few reports conducted to discriminate unique enzymes from typical ones based on novel structure and function. In this study, we discovered an esterase and a novel family through a successive assay of whole cells and crude lysates (oxidative open condition). The screened putative esterases from the meta

BACKGROUND: Staphylococcus aureus is a common cause of clinical mastitis (CM) in dairy cattle. Optimizing the bovine mammary gland microbiota to resist S. aureus colonization is a growing area of research. However, the details of the interbacterial interactions between S. aureus and commensal bacteria, which would be required to manipulate the microbiome to resist infection, are still unknown. This study aims to characterize changes in the bovine milk bacterial community before, during, and afte

BACKGROUND: Antibiotic-resistant Staphylococcus aureus clones have emerged globally over the last few decades. Probiotics have been actively studied as an alternative to antibiotics to prevent and treat S. aureus infections, but identifying new probiotic bacteria, that have antagonistic activity against S. aureus, is difficult since traditional screening strategies are time-consuming and expensive. Here, we describe a new plasmid-based method which uses highly stable plasmids to screen bacteria

This study examined characteristics between Chinese Americans and Korean Americans who received treatment for alcohol use problems, using case records of 103 Chinese Americans and 108 Korean Americans. Findings show that the majority of Chinese Americans and Korean Americans were referred for treatment by the legal system and denied having alcohol problems. Significant differences were found between the groups in income, education, and types and quantity of alcohol use. Participants from neither