김송이 교수
Song-I Kim
연세대학교 내과 · 의학
연구실 소개
김송이 교수의 연구실은 감염병, 특히 다제내성 병원성 박테리아와의 전쟁에서의 진단 및 예후 예측을 중심으로 연구를 진행하고 있습니다. 특히 날카로운 임상적 문제인 카바페넴내성 아크ิน토박터 바우마니아 감염, 세균성 패혈증, 그리고 희귀 피부질환인 올름스타드 증후군의 유전적 기반을 규명하는 데 초점을 맞추고 있습니다. 또한 신기능 평가 및 신장손상의 조기 진단 지표로써의 세균성 캐스티네인 C의 임상적 유용성에 대해서도 깊이 있는 연구를 수행하고 있습니다. 이와 함께 동아시아 인구 특성에 맞는 유전적 소인 분석을 통해 피부질환의 유전적 기반을 규명하고자 하는 다학제적 연구도 진행 중입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Purpose: Acute kidney injury (AKI) is common in critically ill patients. Serum cystatin C has emerged as a reliable marker of AKI. We sought to assess the value of serum cystatin C for early detection and prediction of renal function recovery in patients with sepsis. Materials and Methods: Sepsis patients (113 AKI patients and 49 non-AKI patients) admitted to the intensive care unit (ICU) were included. Serum creatinine and cystatin C levels and glomerular filtration rate were measured on days 0
To assess the risk factors for carbapenem-resistant Acinetobacter baumannii (CRAB)bacteremia and for 30-day mortality in patients with CRAB bacteremia in the intensive care unit (ICU), we conducted a retrospective study in the ICU at Severance Hospital in Korea from January 2008 to December 2009. Patients who acquired CRAB bacteremia in the ICU were enrolled as the case group and patients whose specimens of blood culture,sputum/endotracheal aspirate and urine revealed no AB were enrolled as cont
Purpose: Atopic dermatitis (AD) is a chronic, relapsing eczematous inflammatory skin disease. Mutations in the filaggrin gene (FLG) are major predisposing factors for AD. Ethnic differences exist between Asian and European populations in the frequency and spectrumof FLG mutations. Moreover, a distinct set of FLG mutations has been reported in Asian populations. The aim of this study was to examine the spectrum of FLG mutations in Koreans with AD. We also investigated the association of FLG mutat
Purpose: We investigated the characteristics of lung allocation and outcomes of lung transplant (LTx) according to the Korean urgencystatus. Materials and Methods: LTx registration in the Korean Organ Transplantation Registry (KOTRY) began in 2015. From 2015 toJune 2017, 86 patients who received LTx were enrolled in KOTRY. After excluding one patient who received a heart-lung transplant,85 were included. Subjects were analyzed according to the Korean urgency status. Results: Except for Status 0,
Background/Aims: Delayed diagnosis and treatment of smear-negative pulmonary tuberculosis (TB) are major concerns for TB control. We evaluated characteristics of patients with smear-negative pulmonary TB who received a delayed diagnosis and identified risk factors that may have contributed to this delay. Methods: We reviewed medical records of patients with smear-negative culturepositive pulmonary TB treated at a tertiary care hospital in South Korea between January 2017 and December 2018. Patie
Olmsted syndrome (OS) is a rare congenital skin disorder characterized by severe palmoplantar and periorificial keratoderma, alopecia, onychodystrophy, and severe pruritus. Recently, pathogenic ‘gain-of-function’ mutations of the transient receptor potentialvanilloid 3 gene (TRPV3), which encodes a cation channel involved in keratinocyte differentiation and proliferation, hair growth, inflammation, pain and pruritus, have been identified to cause OS. Due to the rarity, the pattern of inheritance
Purpose: We aimed to determine the relationship between environmental exposure and nontuberculous mycobacterial pulmonarydisease (NTM-PD) in Korea. Materials and Methods: A group of 150 patients with NTM-PD and a control group of 217 patients with other respiratory diseaseswere prospectively enrolled between June 2018 and December 2020 in Seoul, Korea. They were surveyed with a standardizedquestionnaire, and their medical records were reviewed. Odds ratio (OR) and 95% confidence intervals (CI) w
Purpose: Anastomotic airway complications are a major cause of morbidity and mortality after lung transplantation (LTx). In this study, the authors identified types and clinical outcomes of airway complications after LTx. Materials and Methods: All bronchial anastomotic complications were analyzed in a total of 94 LTx cases involving 90 recipients who underwent surgery between July 2006 and May 2014. Fifteen LTx cases (14 recipients) with incomplete medical records for fiberoptic bronchoscopy (F
Purpose: Endobronchial metastasis is defined as documented extrathoracic malignancies metastatic to the endobronchus within a bronchoscopically visible range. Although the clinical and radiologic findings of endobronchial metastasis are similar to primary lung cancer, treatment and prognosis may be different. We hereby investigated the clinical, radiologic and bronchoscopic aspects of endobronchial metastases (EBM) in Korean patients. Materials and Methods: A total of 43 patients with EBM who un
Purpose: Isoniazid (INH) mono-resistant tuberculosis (Hr-TB) is a highly prevalent type of drug-resistant TB, possibly associatedwith unfavorable treatment outcomes. However, definitive guidelines on an optimal treatment regimen and duration for Hr-TBare currently under discussion. We evaluated the characteristics and treatment outcomes of Hr-TB patients. Materials and Methods: We retrospectively reviewed the medical records of Hr-TB patients treated at a South Korean tertiary referralhospital f
Purpose: Calcineurin inhibitor (CNI) use has improved lung transplantation outcomes. However, significant perioperative complicationsin patients receiving CNI can deteriorate the early course of lung transplantation. To date, there is no consensus regardingthe optimal agent for the induction regimen after lung transplantation. We aimed to determine the efficacy of basiliximab inductionwith delayed CNI initiation in the prevention of acute complications without compromising immunosuppression inhi
Purpose: Recent history of malignancy without 5-year disease-free interval is an absolute contraindication for lung transplantation(LTx). However, in rare cases, lung cancer may be incidentally diagnosed in the explanted lung of recipients. We evaluatedthe prevalence, 5-year survival, and prognosis of incidental lung cancer after LTx. Materials and Methods: Medical records of patients who underwent LTx at Severance Hospital between January 1, 2012 and June30, 2019 were reviewed. Patients with in
Background: Recent reports have suggested that pneumonitis is a rare complication following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, its clinical features and outcomes are not well known. The aim of this study was to identify the clinical characteristics and outcomes of patients with vaccine-associated pneumonitis following vaccination against SARS-CoV-2. Methods: In this nationwide multicenter survey study, questionnaires were distributed to pul
This paper presents adoption process for GSCM (Green Supply Chain Management) in Korean manufacturing companies by analyzing their sustainability reports. At first, we developed GSCM evaluation index from two different frameworks, sustainability evaluation framework focusing on environmental side and strategy and activities in GSCM. Based on this, we analyzed 158 sustainability reports of Korean manufacturing firms published from 2008 to 2012. As a result, we observed that the adoption process f
Objectives: The purposes of this study were to analyze the trade newspapers related to ‘recognition of the dental hygienist as the healthcare professional‘ using R program and to identify opinions of groups concerned with dental hygienists. Methods: This study was designed with contents analysis and cross-sectional. The subjects of the study were the articles for the last three years in medical and dental newspapers about the recognition of the dental hygienist as the healthcare professional. Th
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