김세훈 교수
Soo Hoon Kim
연세대학교 병리학과 · 의학
연구실 소개
김세훈 교수의 연구실은 전자구조 분석을 기반으로 한 나노물질의 표면 및 계면 반응 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 고해상도 광전자분광법(HRPES)을 활용해 그래핀과 같은 2차원 물질의 화학적 기능화 및 결합 특성에 대한 정밀 분석을 수행하며, 이는 나노전자소자 및 반도체 소재 개발에 기여하고 있습니다. 또한 신경계 질환, 특히 어린이 간질과 뇌종양의 분자 기전 및 영상 진단 기법에 대한 다학제적 연구도 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Chemically modified epitaxial graphene (EG) by azidotrimethylsilane (ATS) was investigated using high-resolution photoemission spectroscopy (HRPES). Through the spectral analysis, we clearly confirmed that EG is modified by thermally generated nitrene radicals and found that the bonding nature between the nitrene radicals and EG is covalent. As we observe bonding nature of N 1s peaks, we found that two distinct N peaks can be clearly distinguished in the spectra. Using a covalently bound stretch
PURPOSE: To determine if defects in mitochondrial respiratory chain enzyme complexes (MRCs) contribute to the etiology of childhood epilepsy. METHODS: We reviewed the clinical and laboratory features of 48 epileptic patients (23 male, 25 female) with MRC defects that were confirmed by biochemical assays using muscle biopsies. RESULTS: (1) Thirty-five cases (72.9%) were MRC I deficient, one case (2.1%) was MRC II deficient, 11 cases (22.9%) were MRC IV deficient, and one case (2.1%) had combined
PURPOSE: The purpose of this study is to determine the sensibility of each imaging tool in identifying focal cortical dysplasia (FCD) in children and adolescents with epilepsy and to define the prognostic factors of pediatric and adolescent epilepsy surgery. METHODS: We identified 48 children with FCD who underwent resective surgery and analyzed their preoperative data. The results of various anatomic and functional neuroimaging studies were compared for accuracy in locating the lesion. We also
A mixed-basis band-structure interpolation scheme for fcc d-band metals has been extended to include fluorite-structure (${\mathrm{CaF}}_{2}$) compounds by incorporating more plane waves in the basis set. Since the fluorite and fcc structures belong to the same space group, the interpolation scheme originally developed for fcc d-band metals is also capable of generating fluorite band structures. The interpolation parameters for ${\mathrm{NiSi}}_{2}$, ${\mathrm{AuAl}}_{2}$, ${\mathrm{AuGa}}_{2}$,
Stereotactic radiosurgery has been an important treatment modality in the treatment of pituitary adenomas. However, it has the disadvantage of a delayed effect on hormonal normalization compared with microsurgical resection of functioning pituitary adenomas. To define the efficacy of radiosurgery in the treatment of functioning pituitary adenomas, 37 cases with a mean follow-up duration of 26.9 months were analyzed. There were 18 prolactinomas, 11 cases with acromegaly, and 8 cases with Cushing
BACKGROUND: Spinal cord glioma grade IV is a rare, diffuse midline glioma. H3 K27M-mutant was classified in a different entity in the 2016 World Health Organization (WHO) classification recently. No reports about prognosis of spinal cord glioma grade IV are available yet. OBJECTIVE: To analyze the prognostic factors for spinal cord glioma grade IV. METHODS: Twenty-five patients with spinal cord glioma of grade IV who underwent surgery in a single institute were selected. All grade IV spinal cord
In this paper, we consider the frequency assignment problem (FAP) in a cellular mobile communication system under the assumption that there is no channel interference between two cells separated by more than a certain distance. This special structure is observed in most cellular systems. To handle the considered FAP, we use the pattern approach which fits naturally to the problem. Based on this approach, we are able to formulate the considered FAP into a manageable optimization problem and propo
The histopathologic type of lung cancer is known to be correlated with tumor behavior and prognosis. However, this classification is subjective and no specific molecular markers have been identified. The aim of this study was to identify protein markers in different types of nonsmall cell lung cancers. Two-dimensional polyacrylamide gel electrophoresis analysis was performed with paired samples of three squamous cell carcinomas, three adenocarcinomas, four large cell carcinomas, and four basaloi
OBJECTIVES/HYPOTHESIS: The objective of this prospective study was to confirm the validity of transoral robotic supraglottic partial laryngectomy as a conservation surgery for treating supraglottic cancer. STUDY DESIGN: Prospective case study. METHODS: Between December 2009 and November 2011, 16 patients were enrolled in this study. Acoustic waveform analysis was conducted and Voice Handicap Index 10 was measured to assess voice status. Videopharyngogram study and the functional outcome swallowi
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