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함수연 교수

Su Yeon Ham

성균관대학교 의학과 · 의학

연구실 소개

함수연 교수의 연구실은 의료 영상 분석과 생물학적 기전 탐구를 융합한 연구를 주도하고 있습니다. 특히 유방 조영 검사 및 흉부 CT를 활용한 암 조기 진단 기술 개발과 함께, 염증성 질환 및 혈관 기능 이상의 세밀한 분자 기전을 규명하고자 합니다. 신경영상 기반 진단 정확도 향상과 함께, 혈액 생물학적 마커를 활용한 폐질환 구별 진단법 개발에도 기여하고 있습니다.

의료영상 분석유방암 조기진단염증성 폐질환혈관 기능 이상생물학적 마커

연구 현황

논문 수
77
총 인용 수
551
최근 5년 논문
31
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
31총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
86총합
20222023202420252026

주요 논문

15
1
논문|인용수 135·2018
Detection of masses in mammograms using a one-stage object detector based on a deep convolutional neural network
Hwejin Jung, Bumsoo Kim, Inyeop Lee, Minhwan Yoo, Junhyun Lee, Soo‐Youn Ham, Ok-Hee Woo, Jaewoo Kang
SJR Q1PLoS ONEOA

Several computer aided diagnosis (CAD) systems have been developed for mammography. They are widely used in certain countries such as the U.S. where mammography studies are conducted more frequently; however, they are not yet globally employed for clinical use due to their inconsistent performance, which can be attributed to their reliance on hand-crafted features. It is difficult to use hand-crafted features for mammogram images that vary due to factors such as the breast density of patients an

Artificial IntelligenceComputer Science
2
논문|인용수 64·2018
Diagnostic Value of Contrast-Enhanced Digital Mammography versus Contrast-Enhanced Magnetic Resonance Imaging for the Preoperative Evaluation of Breast Cancer
Eun Young Kim, Inyoung Youn, Kwan Ho Lee, Ji‐Sup Yun, Yong Lai Park, Chan Heun Park, Juhee Moon, Seon Hyeong Choi, Yoon Jung Choi, Soo‐Youn Ham, Shin Ho Kook
SJR Q2Journal of Breast CancerOA

CEDM demonstrated a diagnostic performance comparable with CEMRI in depicting index cancers, secondary cancers, and occult cancer in the contralateral breast. CEDM demonstrated similar changes in surgical management compared with CEMRI.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
3
논문|인용수 34·2019
Contrast enhanced digital mammography versus magnetic resonance imaging for accurate measurement of the size of breast cancer
Inyoung Youn, Seon-Hyeong Choi, Yoon Jung Choi, Ju Hee Moon, Hee Jin Park, Soo‐Youn Ham, Chan Heun Park, Eun Young Kim, Shin Ho Kook
SJR Q1British Journal of RadiologyOA

To compare the accuracy of contrast-enhanced digital mammography (CEDM) and MRI, including maximal intensity projection (MIP) images, for measuring the tumour size of breast cancer. We included 52 females (mean age, 50.9 years) with surgery due to breast cancer, and measured maximum diameter of main mass on mediolateral oblique (MLO) and craniocaudal (CC) views of mammography and CEDM; sagittal, axial MIP images, and early dynamic contrast-enhanced MRI (CEMRI) before surgery. Bland–Altman plot,

Pulmonary and Respiratory MedicineMedicine
4
논문|인용수 28·2020
Preoperative evaluation of mammographic microcalcifications after neoadjuvant chemotherapy for breast cancer
Eung Yeop Kim, Sung‐Im Do, Jong-Min Yun, Y.L. Park, C.H. Park, Juhee Moon, In Young Youn, Young‐Gwan Choi, Soo‐Youn Ham, Shin Ho Kook
SJR Q2Clinical Radiology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
5
논문|인용수 25·2019
Doxorubicin inhibits PD-L1 expression by enhancing TTP-mediated decay of PD-L1 mRNA in cancer cells
Dong Jun Kim, Ji Hun Jang, Soo‐Youn Ham, Seong Hee Choi, Sung Soon Park, So Yeon Jeong, Beom Chang Kim, Do Yong Jeon, Byung Ju Lee, Byung Kyun Ko, Jeong Woo Park, Wha Ja Cho
SJR Q2Biochemical and Biophysical Research Communications
OncologyMedicine
6
논문|인용수 19·2019
Clinical characteristics and chest computed tomography findings of smear-positive and smear-negative pulmonary tuberculosis in hospitalized adult patients
Jong Hun Kim, Min Ja Kim, Soo‐Youn Ham
SJR Q3MedicineOA

Pulmonary tuberculosis (PTB) continues to be one of the significant public health threats with significant morbidity and mortality. The present study was aimed to assess the clinical characteristics and chest computed tomography (CT) findings of smear-positive and smear-negative PTB in hospitalized adult patients.Hospitalized adult patients diagnosed with PTB by positive Mycobacterium tuberculosis growth on acid-fast bacilli culture from bronchial aspiration or sputum from 2015 to 2017 were revi

Infectious DiseasesMedicine
7
논문|인용수 14·2022
DRG2 Depletion Promotes Endothelial Cell Senescence and Vascular Endothelial Dysfunction
Anh-Nhung Le, Seong-Soon Park, Minh-Xuan Le, Unn Hwa Lee, Byung Kyun Ko, Hye Ryeong Lim, Ri Yu, Seong Hee Choi, Byung Ju Lee, Soo‐Youn Ham, Chang Man Ha, Jeong Woo Park
SJR Q1International Journal of Molecular SciencesOA

Endothelial cell senescence is involved in endothelial dysfunction and vascular diseases. However, the detailed mechanisms of endothelial senescence are not fully understood. Here, we demonstrated that deficiency of developmentally regulated GTP-binding protein 2 (DRG2) induces senescence and dysfunction of endothelial cells. DRG2 knockout (KO) mice displayed reduced cerebral blood flow in the brain and lung blood vessel density. We also determined, by Matrigel plug assay, aorta ring assay, and

ImmunologyImmunology and Microbiology
8
논문|인용수 8·2018
The role of serum procalcitonin in the differential diagnosis of pneumonia from pulmonary edema among the patients with pulmonary infiltrates on chest radiography
Young Kyung Yoon, Min Ja Kim, Kyung‐Sook Yang, Soo‐Youn Ham
SJR Q3MedicineOA

The aim of this study is to evaluate the usefulness of serum procalcitonin (PCT) as a diagnostic biomarker for distinguishing pneumonia from pulmonary edema in patients presenting with pulmonary infiltrates on chest radiography.A comparative study was performed retrospectively in a university-affiliated hospital, from May, 2013 to April, 2015. Adult patients (≥18 years) who showed pulmonary infiltrates on chest radiography and had blood tests with C-reactive protein (CRP), erythrocyte sedimentat

EpidemiologyMedicine
9
논문|인용수 5·2020
Clinical implications of thoracic duct dilatation in patients with chronic liver disease
Seung Woon Park, Tae Hyung Kim, Soo‐Youn Ham, Soon Ho Um, Hyun Gil Goh, Sunhye Lee, Han Ah Lee, Sun Young Yim, Yeon Seok Seo, Hyung Joon Yim, Hyonggin An, Yu‐Whan Oh
SJR Q3MedicineOA

This study aimed to investigate the association between the degree of thoracic duct dilatation and the progression of chronic liver disease.In this cross-sectional and retrospective study, 179 patients (mean age, 60.9 years; 114 men) with chronic liver disease who underwent chest CT were enrolled. Dilatation of the left distal thoracic ducts (DTD) was measured and divided into the following 3 grades according to the maximum transverse diameter: grade 0, invisible thoracic duct; grade 1, visible

SurgeryMedicine
10
논문|인용수 2·2024
Deep Learning-Based Slice Thickness Reduction for Computer-Aided Detection of Lung Nodules in Thick-Slice CT
Jong-Hun Jeong, Doohyun Park, Jung‐Hyun Kang, M Kim, Hwa-Young Kim, Woosuk Choi, Soo‐Youn Ham
SJR Q2DiagnosticsOA

BACKGROUND/OBJECTIVES: Computer-aided detection (CAD) systems for lung nodule detection often face challenges with 5 mm computed tomography (CT) scans, leading to missed nodules. This study assessed the efficacy of a deep learning-based slice thickness reduction technique from 5 mm to 1 mm to enhance CAD performance. METHODS: In this retrospective study, 687 chest CT scans were analyzed, including 355 with nodules and 332 without nodules. CAD performance was evaluated on nodules, to which all th

Pulmonary and Respiratory MedicineMedicine
11
논문|인용수 2·2024
Patch-wise vector quantization for unsupervised medical anomaly detection
Taejune Kim, Yun-Gyoo Lee, Inho Jeong, Soo‐Youn Ham, Simon S. Woo
SJR Q1Pattern Recognition Letters
Artificial IntelligenceComputer Science
12
논문|인용수 1·2002
Hepatic Segments II and III Mimicking a Lung Mass: Diagnosis of a Normal Variant Using Reformatted Multiplanar CT Images
Soo‐Youn Ham, Gregory W. Gladish, Jeremy J. Erasmus
SJR Q3Journal of Computer Assisted Tomography

We describe a patient misinterpreted to have a lung mass on CT owing to extension of hepatic segments II and III between the diaphragm and spleen. This report underscores the importance of being aware of this normal anatomic variant and the utility of two-dimensional multiplanar reformation in interpretation of abnormalities in the region of the thoracoabdominal junction.

HepatologyMedicine
13
논문|인용수 0·2018
P3.17-04 Dealing with the N2 Disesase in Non- Small Cell Lung Cancer- on the Edge.
Soo‐Youn Ham, Sang Won Shin, Byung Kyun Ko
SJR Q1Journal of Thoracic OncologyOA
Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 0·2026
Suggestion for optimizing chest CT evaluation following the screening chest radiography for health surveillance
Soo‐Youn Ham
European Society of RadiologyOA
Pulmonary and Respiratory MedicineMedicine
15
논문|인용수 0·2005
The imaging follow-up of ACR category 3 lesions in screening work up
Soo‐Youn Ham, Soo Young Chung, Ko Byung-Kyun, Ik Yang, Hyoung Jung Kim

Poster: ECR 2005 / B-831 / The imaging follow-up of ACR category 3 lesions in screening work up by: S.-Y. Ham, S. Y. Chung, B.-K. Ko, I. Yang, H. J. K. Kim; Seoul/KP

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

Pulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingArtificial IntelligenceOncologyInfectious DiseasesHepatology

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