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Purpose: The purpose of this study was to define the predictive factors for the early progression of androgen independent prostate cancer in patients receiving intermittent androgen deprivation(IAD) therapy. Materials and Methods: A total of 101 patients(stages A to C in 29 and stage D in 72), who had completed at least 1 cycle of IAD, were included. A variety of possible prognostic factors, such as age, initial prostate-specific antigen(PSA) and testosterone, Gleason score, lymph node or bone m

Abstract Background Tumor-infiltrating lymphocytes (TILs) have been recognized as prognostic and predictive biomarkers in breast cancer. However, challenges such as interobserver variability and lack of standardized cut-off values have limited their clinical implementation. Recent advancements in artificial intelligence (AI)-based pathology have shown potential to enhance reproducibility and objectivity in TIL quantification. Concurrently, circulating tumor DNA (ctDNA) has emerged as a minimally