안석균 교수

ObjectiveaaThe Structured Interview for Prodromal Syndrome (SIPS) from Yale University is intended to diagnose prodromal syndrome of psychosis and to measure the severity of prodromal symptoms. Here, a Korean version of SIPS is presented, and its reliability, validity, and factor structures are examined using a representative Korean sample. MethodsaaThe Korean version of SIPS was administered to 40 participants over a period of 1 year. The inter-rater reliability and internal consistency of the

Individuals at ultra-high-risk (UHR) for psychosis have become a major focus for research designed to explore markers for early detection of and clinical intervention in schizophrenia. In particular, structural magnetic resonance imaging studies in UHR individuals have provided important insight into the neurobiological basis of psychosis and have shown the brain changes associated with clinical risk factors. In this review, we describe the structural brain abnormalities in magnetic resonance im

Objective: We designed a nationwide study with limited exclusion criteria to investigate the prevalence of metabolic syndrome (MetS) in Korea and its relationship with antipsychotic medications. Methods: This multicenter, cross-sectional, and observational study included patients diagnosed with schizophrenia or schizoaffective disorder. Sixteen hospitals enrolled 845 patients aged 18 to 65 years prescribed any antipsychotic medication between August 2011 and August 2013. MetS was diagnosed using

Objective: Psychosocial dysfunction was a nettlesome problem of schizophrenia even in their prodromal phase as well as in their first-episode. In addition, its relations with psychopathology were not determined. The aim of the present study was to examine whether the social and role function impairment was found in ultra-high risk for psychosis (UHR) individuals as well as first-episode schizophrenia patients and to explore its relations with psychopathology. Methods: Thirty-seven normal control

Objective Improving quality of life is an important goal in the treatment of schizophrenia. In previous research, quality of life has been reported to be compromised in patients with schizophrenia. The aim of this study was to investigate whether quality of life may be impaired in first-episode schizophrenia patients and to identify the associated factors of quality of life in first-episode schizophrenia. Methods Forty-eight patients with first-episode schizophrenia and 20 normal controls were r

Objective It was proposed that the ability to recognize facial emotions is closely related to complex neurocognitive processes and/or skills related to theory of mind (ToM). This study examines whether ToM skills mediate the relationship between higher neurocognitive functions, such as reasoning ability, and facial emotion recognition. Methods A total of 200 healthy subjects (101 males, 99 females) were recruited. Facial emotion recognition was measured through the use of 64 facial emotional sti

Many researchers have used cue reactivity paradigm to study alcohol craving. But the difference of craving response to drinks between alcoholic patients and social drinkers was little evaluated. To investigate characteristics of alcohol-related visual cues which induce alcohol craving in alcoholism, we examined the response of subjects to alcohol-related cues considering qualitative aspects. The authors developed 27 photographs related to alcohol as candidate visual cues. Thirty five patients wi

Objective Attributional style, especially external personal attribution bias, was found to play a pivotal role in clinical and non-clinical paranoia. The study of the relationship of the tendency to infer/perceive hostility and blame with theory of mind skills has significant theoretical importance as it may provide additional information on how persons process social situations. The aim of this study was whether hostility perception bias and blame bias might be associated with theory of mind sk

Objective: Psychosocial dysfunction was a nettlesome of schizophrenia even in their prodromal phase as well as first episode and its relations with psychopathology were not determined. The aim of the present study was to examine whether the social and role function impairment was found in ultra-high risk for psychosis (UHR) individuals as well as first-episode schizophrenia patients and to explore its relations with psychopathology. Methods: Thirty-seven normal controls, 63 UHR participants and

Objective The Reading the Mind in the Eyes Test (RMET) was developed by using Caucasian eyes, which may not be appropriate to be used in Korean. The aims of the present study were 1) to develop a Korean version of the RMET (K-RMET) by using Korean eye stimuli and 2) to examine the psychometric properties of the Korean-translated version of the RMET and the K-RMET.Methods Thirty-six photographs of Korean eyes were selected. A total of 196 (101 females) healthy subjects were asked to take the Kore

본 논문은 한국형 알고리듬 개발 사업내용과 기본계획, 조직구성, 알고리듬 개발의 기본원칙, 개발방법, 제한점 및 사용시 주의점에 대해 언급하고자 하였다. 이 사업은 대한정신약물학회와 대한정신분열병학회가 공동으로 주관하였으며 국내 현실에 적합하며, 환자에게는 질적으로 우수한 약물치료가 될 수 있는 한국형 주요 정신질환(정신분열병, 양극성 장애)의 약물치료에 대한 한국형 알고리듬 개발을 시작하였다. 알고리듬이 여러 가지 장점을 지니고 있음에도 불구하고, 여러 가지 제한점과 문제점도 동시에 지니고 있기 때문에 개발 단계에서부터 알고리듬이 지향하는 목표, 그리고 목표에 따른 구체적인 개발 방법에 대한 설계를 소개할 필요가 있었다. 이러한 임상지침서는 최신 설문기법을 이용하였으며 현재 가장 잘 알려진 임상 표준치료법을 반영하였다. 이러한 결과는 한국형 주요 정신질환 환자에 관련되어 있는 임상가뿐만 아니라 정신건강 교육자, 보건전문가들에게도 실제적인 근거를 제시할 수 있다. 본 알고리듬 사업은

Objective Biased attribution styles of assigning hostile intention to innocent others and placing the blame were found in schizophrenia. Attribution styles in individuals at ultra-high risk (UHR) for psychosis, however, have been less studied especially for its association with various psychological factors. We investigated whether UHR individuals show increased hostility perception and blaming bias and explored the associations of these biased styles of attribution with the factor structure of

본 연구 결과는 한국어판 모호한 의도-적개심 설문지가 우리나라 일반 성인에게서도 의도가 다른 상황에 대해 다른 사람을 탓하고 적개심을 가지는 것을 평가하기에 신뢰할 만하고 타당함을 보이고 있다. 향후 한국어판 모호한 의도-적개심 설문지의 분별 타당도를 평가하기 위하여 편집형 정신분열증 환자들을 대상으로 한 비교연구가 필요하겠다.

To explore whether or not patients with schizophrenia display a more profound impairment of negative emotion processing, we assessed the implicit evaluation of positive and negative emotional stimuli. Twenty patients with schizophrenia (9 paranoid, 11 non-paranoid) and 22 normal controls were instructed to classify emotional pictures according to the intrinsic valence if the pictures were black and white. If the stimuli were color-filtered, participants were instructed to press the positive/nega