김수경 교수

Mesenchymal stem cells (MSCs) have an extensive migratory capacity for gliomas, which is comparable to that of neural stem cells. Among the various types of MSCs, human adipose tissue-derived MSCs (hAT-MSC) emerge as one of the most attractive vehicles for gene therapy because of their high throughput, lack of ethical concerns, and availability and ease of isolation. We evaluated the therapeutic potential and safety of genetically engineered hAT-MSCs encoding the tumor necrosis factor-related ap

The association between subclinical hypothyroidism and cardiovascular disease and the beneficial effect of levothyroxine replacement in subclinical hypothyroidism are still under debate. The present study was designed to determine whether subclinical hypothyroidism is associated with an increase in the intima-media thickness of the common carotid artery (C-IMT) and whether thyroid hormone replacement can reverse this change in the C-IMT. Patients with newly-diagnosed subclinical (n=36) and overt

CONTEXT: The association between nonalcoholic fatty liver disease (NAFLD) and subclinical atherosclerosis in type 2 diabetes is controversial. OBJECTIVE: The objective of the study was to investigate the participation of insulin resistance in the association of NAFLD and the carotid atherosclerotic burden in a large cohort of patients with type 2 diabetes. DESIGN, SETTING, AND PATIENTS: This was an observational study performed in 4437 consecutively enrolled patients with type 2 diabetes. MAIN O

OBJECTIVE: To investigate whether waist circumference (WC), calf circumference (CC), and waist-to-calf ratio (WCR) are associated with carotid atherosclerosis in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was an observational study performed in 3,694 Korean patients with type 2 diabetes. Anthropometric measures and carotid ultrasound were performed on each subject. Carotid atherosclerosis was defined as having a clearly isolated focal plaque or mean carotid intima-media thi

AIMS/INTRODUCTION: We aimed to determine the hospital-based prevalence and clinical features of fulminant type 1 diabetes mellitus in Korea. MATERIALS AND METHODS: We identified all patients with diabetes who regularly visited the Endocrinology outpatient clinics at eight centers for a period >1 year between January 2012 and June 2017. We investigated their medical records retrospectively. RESULTS: During this period, 76,309 patients with diabetes had been regularly followed up. Among them, 913

The results of our study suggest that decreased vital capacity in Korean adult male subjects is associated with MetS, irrespective of obesity.

Cigarette smoking is associated with higher triglyceride in Korean men, with the most dramatic effect seen in current smokers with a smoking history of more than 20 pack-years. HDL-C were also lower in current smokers with more than 20 pack-years.

Leptin has been linked to adiposity, insulin resistance, and coronary artery disease (CAD). We examined whether the leptin concentrations are associated with the risk of CAD and metabolic syndrome (MS). The plasma leptin concentrations were measured in 556 diabetic patients (341 men and 215 women). The odds ratio (OR) of CAD and MS were increased on moving from the lowest quartile (Q1) of leptin concentration to the highest quartile (Q4) and remained significant after adjusting for age, sex, BMI

이 논문은 여성적 글쓰기의 구체적 방식을 연구하고자 하는 시도로서 ‘여행’이라는 체험이 여성적 글쓰기를 통해 구체적으로 어떻게 드러나는지, 남성적 글쓰기와는 어떤 차이가 있는지를 살펴보고자 한 글이다. 그 대상으로는 19세기에 창작된 여성 기행가사 작품으로 작가가 밝혀진 <부여노정기> <이부인기행가사> <금행일기> 세 편을 주된 대상으로 하되, 가사로서의 특징을 드러내기 위해 부분적으로 <호동서낙기>와 같은 동시대 산문기록과 비교하였다. 이 세 작품은 19세기 당시 여성에게 있어서 여행은 어떤 의미로 다가왔는지 보여주고 있으며 아쉬우나마 19세기 여성 기행가사의 지형도를 이루고 있다는 점에서 중요하다. 그 결과, 여성 기행가사에 나타나는 서술상의 특징으로 여행지에서 만나게 되는 새로운 경험만큼이나 가족 중심적 서술이 두드러진다는 점, 여행 체험은 적절하게 글로써 표현되어야 한다는 전통적 관념에 의해 문학적 표현의 욕구가 강하게 드러난다는 점, 이념이나 역사적 배경보다는 정서적 체험

Chronic low back pain (CLBP) is a major problem throughout the world and getting worse because of population increase and aging. The cost of treatment increases as the population of people with CLBP increases. This study aimed to examine the effect of auricular acupressure (AA) on pain and disability in elders with chronic low back pain. The randomized, single-blinded, and placebo-controlled study was conducted on 51 elders with CLBP in South Korea from June 2019 to August 2019. The experimental

필자는 이른바 ‘동요 황금시대’라고 일컬어졌던 1920~30년대의 동요의 실상과 미학적 가치를 탐구해오던 바, 현재까지 즐겨 불리는 동요의 상당수가 해방 이후에 창작된 것보다는 오히려 근대 초기이자 아동문학의 초창기였던 1920~30년대에 창작된 것이 라는 사실을 발견하게 되었다. 그리하여 1920~30년대 동요 가운데 과연 얼마만큼의 작품이, 그리고 어떤 작품이 현재까지 면면히 수용되고 있는지 추적해본다면 근대 초기 동요의 전통과 의의를 밝히는데 실증적으로 도움이 되리라고 생각하였다. 대상으로는 1차 교육과정부터 7차 교육과정까지 초등학교(국민학교) 음악교과서를 대상으로 하였고, 노랫말에 주목하여 음악적인 측면은 고려하지 않았음을 밝혀둔다. 그 결과, 초등학교 음악교과서에 수록된 노래 가운데는 창작 동요의 비중이 단연 높고, 창작 동요 가운데서는 1920~30년대, 이른바 동요황금시대라고 불렸던 시대에 창작된 작품이 높은 비중을 차지한다는 사실을 밝혔다. 6차 교육과정까지는 창작

This study aims to analyse girl’s textbooks which had been used in schools during the period from 1896~1910. The urgent demand of that period was the development of national power and children’s education for nation’s future against Japanese invasion. At that time, women’s education were focused on producing wise mother and good wives in the modern sense in order to raise their children. The newspapers and magazines in that period claimed that women, as the civilized citizen, had to be educated

Objectives: The prevalence of obesity among adolescents has been continuously increasing for the last 10 years. This study aimed to reveal individual- and school-level factors associated with the risk of obesity among Korean adolescents. Methods: We used recently collected data over a period of 3 years (2017-2019) through the Korea Youth Risk Behavior Survey. In total, 148,731 adolescents from 2,399 middle and high schools were included. The complex sample hierarchical logistic regression analys