이수민 교수
Sumin Lee
서울대학교 · 공학
연구실 소개
이수민 교수의 연구실은 주로 환경 오염 물질의 생물학적 분해를 핵심으로 삼고 있으며, 특히 흰가루버섯류(white rot fungi)를 활용한 유해 화학물질인 BPA, DBP, 메토크시클로르 등의 생분해 기술을 연구하고 있습니다. 또한, 생체적합성과 기계적 유연성을 갖춘 마이크로소재, 특히 뜨개질형(shape-memory alloy) 섬유를 활용한 웨어러블 재활 보조기구 개발에도 주력하고 있습니다. 이는 환경 정화와 동시에 환자 중심의 의료 기술 혁신을 동시에 추구하는 융복합 연구입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Two lignin-degrading basidiomycetes, Stereum hirsutum and Heterobasidium insulare, were used to degrade bisphenol A (BPA) in culture, and the estrogenic activity of the degradation products was examined using MCF-7 cell proliferation assays (E-screen) and analysis of pS2 mRNA expression in MCF 7 cells. Both S. hirsutum and H. insulare showed high resistance to BPA 100 ppm, and their mycelial growth was fully completed within 8 d of incubation at 30 degrees C. It took 7 to 14 d to achieve complet
In this study, white rot fungus, Polyporus brumalis, was applied to degrade dibutyl phthalate (DBP), a major environmental pollutant. The degradation potential and resulting products were evaluated with HPLC and GC/MS. As DBP concentration increased to 250, 750, and 1,250 microM, the mycelial growth of P. brumalis was inhibited. However, growth was still observed in the 1,250 microM concentration. DBP was nearly eliminated from culture medium of P. brumalis within 12 days, with 50% of DBP adsorb
Attention-deficit hyperactivity disorder (ADHD) is one of the most common childhood psychiatric conditions. In 2007, the Korean Academy of child and Adolescent Psychiatry developed Korean ADHD practice parameter. Advances in the scientific evidence of ADHD caused practice parameter to be modified and updated. The present guidelines developed by ADHD translational research center summarize current literature for the treatment of ADHD in children and adults. This parameter includes the clinical ev
Abstract We developed the knitted shape-memory alloy (SMA) as a flexible actuator and applied it to a soft wearable exoglove for rehabilitation assistance. Based on user needs and anthropometric data, we custom-designed the exoglove for three hemiplegic patients using the knitted-SMA actuator and evaluated its bending performance, gripping force and wearability under the four simulation conditions (S1–S4). To address the specific needs, both SMA plain- and double-knit modules were applied to the
Osteoarthritis is a chronic disease that affects joint cartilage and can cause severe pain and disability. Minor neglected injuries may also result in other diseases that affect daily life. Various attempts have been made to develop wearable auxiliary devices using functional fabrics, but few have simultaneously provided both heat and pressure. Using knitted shape memory alloy (SMA) fabric, a module was manufactured that achieved bending and contraction during operation. An elbow brace that simu
The white rot fungus Stereum hirsutum was used to degrade methoxychlor [2,2,2-trichloro-1,1-bis(4-methoxyphenyl)ethane] in culture and the degraded products were extensively determined. The estrogenic activity of the degraded products of methoxychlor was examined using cell proliferation and pS2 gene expression assays in MCF-7 cells. S. hirsutum showed high resistance to methoxychlor 100 ppm, and the mycelial growth was fully completed within 8 days of incubation at 30 degrees C. Methoxychlor in
Abstract As the global population ages, there is an increasing demand for physical assistive devices for the elderly. This study aimed to develop and evaluate a wearable gripping aid for elderly women to assist in their handgrip ability. We developed an actuator module for the hand-gripping aid using a 4D knitted shape memory alloy and attached to a flexible nylon glove. At baseline, we measured the bending angles of the knitted shape memory alloy and the subjects’ fingers while gripping. The be
Shape memory alloys (SMAs) have an innate property that allows them to return to a memorized form when stimulated. They have been recently designed as flexible fabrics for use in wearable assistive devices. This study aimed to develop a rehabilitation assistive glove with good wearability for a hemiplegic patient using a knitted SMA with a high-unidirectional contractile response. We fabricated warp-knitted SMA actuators, which had higher contractile responses than those of weft-knitted SMA. The
Abstract Electronic monitoring systems have been globally adopted to track criminals to ensure public safety efficiently. In this study, we aimed to assess the wearability of an electronic bracelet using multiple evaluation methods, including the evaluation of range of motion (ROM), air gap (AG), and clothing pressure (CP) at the wearer’s wrist, as well as self-scoring of subjective comfort (SC). We recruited eight Korean male participants (N = 8) who were in their 30 s and did not have any musc
Objectives:The objective of this study was to investigate the relationship between restricted, repetitive behaviors and interests (RRBI) and autistic symptoms in Korean high functioning autism spectrum disorder (ASD) children and to examine the structure of RRBI. Methods:Participants included 147 high functioning ASD subjects and 181 unaffected siblings. ASD subjects were divided into two groups based on the presence of RRBI. The domain scores of the Korean version of Autism Diagnostic Interview
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