박성배 교수
Sung Bae Park
서울대학교 신경외과 · 의학
연구실 소개
박성배 교수의 연구실은 척추외과 및 골다공로시스 관련 질환의 메커니즘과 치료 전략을 중심으로 연구를 진행하고 있습니다. 특히 노령 환자에서의 척추 고정 수술에 적합한 신소재 및 약물 치료 전략 개발에 초점을 맞추고 있으며, 골다공로시스가 동반된 환자에서 뼈 형성 촉진제의 임상적 유용성과 수술적 결과의 장기적 추적을 연구하고 있습니다. 또한, 퇄관절 및 척추 질환의 수술적 접근법 개선을 위한 임상 연구와 동물 모델 기반의 기전 연구를 병행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The prevalence of osteoporosis has been increasing globally. Recently surgical indications for elderly patients with osteoporosis have been increasing. However, only few strategies are available for osteoporotic patients who need spinal fusion. Osteoporosis is a result of negative bone remodeling from enhanced function of the osteoclasts. Because bone formation is the result of coupling between osteoblasts and osteoclasts, anti-resorptive agents that induce osteoclast apoptosis may not be effect
Bilateral OVX is a safe method for creating an osteopenic rat model. The significant decrease in BMD appears six weeks after bilateral OVX.
Carcinosarcoma of gallbladder (CSGB) is a rare malignancy characterized by malignant epithelial and mesenchymal components. Its pathogenesis is unknown and most CSGBs are associated with poor survival because the disease normally presents at an advanced stage, and as a result, curative resection is uncommon. This report describes a case that underwent curative resection. A 77-year-old woman presented with right upper quadrant pain. The preoperative diagnosis was gallbladder (GB) cancer, and thus
STUDY DESIGN: A retrospective cohort study of a nationwide sample database. OBJECTIVE: The objective of the present study was to compare the long-term incidence of reoperation for lumbar herniated intervertebral disc disease (HIVD) after major surgical techniques (open discectomy, OD; laminectomy; percutaneous endoscopic lumbar discectomy, PELD; fusion). SUMMARY OF BACKGROUND DATA: HIVD is a major spinal affliction; if the disease is intractable, surgery is recommended. Considering both the agin
STUDY DESIGN: A retrospective cohort study. OBJECTIVE: The objectives of the present study were to examine the changes in the number of surgeries, surgical methods selected, and reoperation rates between the years 2003 and 2008. SUMMARY OF BACKGROUND DATA: The selection of the appropriate surgical method between decompression-only (D) and decompression plus fusion (DF) represents a challenging clinical dilemma in patients with degenerative lumbar spinal spondylolisthesis. DF is selected in great
3.
Endovascular therapy can be successfully used as a primary treatment for the majority of patients with spinal DAVFs. Although it is difficult to perform in some patients, endovascular embolization should be the primary treatment of choice for spinal DAVF.
STUDY DESIGN: Retrospective analysis. OBJECTIVE: The object is to assess the correlation between whole lumbar lordosis (LL) and the segmental angle (SA) after single-level anterior lumbar interbody fusion for degenerative lumbar spondylolisthesis. SUMMARY OF BACKGROUND DATA: The restoration of the SA at lower lumbar spine is meaningful, considering it contributes approximately 60% of LL, and revision surgery due to flat back or adjacent segment pathology was necessary decades after the initial s
OBJECT: The aim of this study was to describe a novel technique for laminoplasty in which translaminar screws are used in the thoracic and lumbar spine. METHODS: The authors first performed a morphometric study in 20 control individuals using 3D reconstructed CT scans and spine simulation software to measure the lengths and diameters of the spaces available for translaminar screw placement from the T-1 to S-1. Based on the results of the morphometric study, the authors then attempted translamina
The design of the PEEK cage used may influence the SA, and this association needs to be considered when using stand-alone PEEK cages.
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