조성범 교수
Sung-Bon Cho
고려대학교 영상의학과 · 의학
연구실 소개
조성범 교수의 연구실은 주로 의료 영상 진단과 종양 생물학의 융합을 목표로 하며, 특히 MRI를 활용한 암 진단 정밀도 향상과 병변의 생물학적 특성 간 연관성 규명에 중점을 두고 있습니다. 간세포암과 신세포암과 같은 암 종양에서의 카드헤린 발현 패atters 분석, 그리고 화학요법 중 발생할 수 있는 유사 전이성 병변(CIFH)의 영상학적 특징 규명 등, 임상적 유의미성 있는 영상 생물지표 발굴에 기여하고 있습니다. 특히 컴퓨터 보조 진단 기술과 고해상도 영상 영역에서의 정밀 진단 기법 개발을 통해 개인 맞춤 치료 전략 수립에 기여하고자 합니다.
연구 현황
연구 성과 추이
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주요 논문
15POHL development is associated with increased number of OBC sessions, and POHL severity was correlated with various biomarkers of SOS.
CIFH should be considered a mimicker of metastasis in patients with gastrointestinal malignancy during chemotherapy. CIFH can be differentiated from metastasis on the basis of gadoxetic acid-enhanced MR and DW imaging findings; an ill-defined margin on HBP images was especially characteristic.
BACKGROUND: We aimed to investigate the efficacy of computer-aided detection (CAD) for MRI in the assessment of tumor extent, lymph node status, and multifocality in invasive breast cancers in comparison with other breast imaging modalities. METHODS: Two radiologists measured the maximum tumor size, as well as, analyzed lymph node status and multifocality in 86 patients with invasive breast cancers using mammography, ultrasound, CT, MRI with and without CAD, and 18-fludeoxyglucose positron emiss
Institutional review board approval and informed consent were obtained. The purpose of the study was to prospectively evaluate magnetic resonance (MR) urethrography for the depiction of obliterative urethral stricture. Twelve patients with obliterative urethral stricture were examined preoperatively with T2-weighted, T1-weighted, and contrast material-enhanced T1-weighted MR imaging of a urethra distended with sterile lubricating jelly. Ten of the 12 patients were examined with conventional retr
Loss or reduced E-cadherin expression and aberrant expression of N-cadherin have been associated with invasiveness of human carcinoma cells and poor prognosis. The role of E- and N-cadherin, however, in hepatocellular carcinoma (HCC) has not yet been elucidated. The aim of the present study was to investigate the expression pattern of E- and N-cadherin in surgically resected HCC specimens according to their relationship with clinicopathological features. The expression patterns of E- and N-cadhe
Background Identification of clinical features to determine the aggressive potential of tumors is highly warranted to stratify patients for adequate treatment. Computed tomography (CT) imaging features of clear cell renal cell carcinoma (ccRCC) may contribute to personalized risk assessment. Purpose To assess the correlation between CT imaging features and Fuhrman grade of ccRCC, and to identify the predictors of high Fuhrman grade in conjunction with tumor size. Material and Methods CT scans of
EVO generally accomplished better results of variceal obturations than EVL or hemoclipping, without serious adverse events. EVO may be an effective modality for control of ectopic variceal bleeding without radiologic intervention or surgery.
Continent urinary diversions have recently become the preferred procedures rather than performing an ileal conduit. Intravenous urography, pouchography, and computed tomography scans are frequently used for postoperative evaluation of patients with bladder carcinoma. During postoperative follow-up imaging studies, the radiologist must keep these 4 facets in mind as his primary focus: 1) the detection of newly developed urothelial tumors, 2) the detection of metastasis, 3) the detection of postop
OBJECTIVE: The aim of this study was to assess the utility of prostate-specific antigen density (PSAD) calculated using magnetic resonance imaging for predicting Gleason score (GS) upgrade in patients with low-risk prostate cancer on biopsy. METHODS: Seventy-three patients were divided into 2 groups according to the concordance between biopsy and prostatectomy GS: group 1 (6/6) and group 2 (6/≥7). Magnetic resonance imaging-based PSAD, prostate volume, prostate-specific antigen (PSA), and age we
BACKGROUND: The safety of gadolinium-based contrast agents is of fundamental importance. PURPOSE: To determine the frequency and severity of immediate-type adverse reactions to approved doses of gadoteridol in patients referred for routine gadoteridol-enhanced MRI in actual clinical practice settings. STUDY TYPE: Prospective, observational. POPULATION: In all, 6163 subjects were enrolled (mean age: 56.7 ± 15.4 years; range: 6-93 years). FIELD STRENGTH/SEQUENCE: 1.5T and 3.0T. ASSESSMENT: Assessm
PURPOSE: To evaluate the feasibility and the outcomes of transjugular percutaneous endovascular treatment of dysfunctional hemodialysis access in patients with chronic kidney disease. METHODS: A total of 50 transjugular treatments in 38 patients with arteriovenous fistulas or arteriovenous grafts from September 2011 to May 2015 were included in this study. Medical records and angiographies were retrospectively reviewed. Success rate, patency rate, procedure time, and complications including inte
Prostate-specific antigen adjusted for transition zone volume is more accurate than prostate-specific antigen density in distinguishing prostate cancer from benign prostatic hyperplasia in men with intermediate serum prostate-specific antigen of 4.1 to 10.0 ng/mL. Determination of transition zone volume by transrectal ultrasonography may be helpful for predicting the probability of positive biopsy results.
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