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고성범 교수

Sung-Bon Ko

고려대학교 신경과 · 의학

연구실 소개

고성범 교수의 연구실은 파킨슨병 환자에서 나타나는 비운동성 증상, 특히 시각 기능 저하와 인지 기능 저하의 기초를 규명하고자 한다. 주로 비약물성 치료와 조기 진단을 목표로 하며, 특히 입체시각(스테레오프시스)과 뇌의 회색질 부위의 변화 간 연관성을 분석하는 데 초점을 맞추고 있다. 또한 파킨슨병의 조기 발병 위험 요인과 비모터 증상 간의 인과관계를 규명하는 데에도 기여하고 있다.

비모터 증상입체시각뇌 구조 변화파킨슨병 조기 진단인지 기능 저하

연구 현황

논문 수
296
총 인용 수
4,204
최근 5년 논문
45
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
45총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
283총합
20222023202420252026

주요 논문

15
1
논문|인용수 67·2012
Validation of the Korean-Version of the Nonmotor Symptoms Scale for Parkinson's Disease
Seong‐Beom Koh, Jae Woo Kim, Hyeo‐Il Ma, Tae‐Beom Ahn, Jin Whan Cho, Phil Hyu Lee, Sun Ju Chung, Joong‐Seok Kim, Do‐Young Kwon, Jong Sam Baik
SJR Q2Journal of Clinical NeurologyOA

The K-NMSS exhibited good reliability and validity for the assessment of non-motor symptoms in Korean PD patients.

NeurologyMedicine
2
논문|인용수 59·2015
Nonmotor symptoms in essential tremor: Comparison with Parkinson's disease and normal control
Seon-Min Lee, Minjik Kim, Hye Mi Lee, Kyum‐Yil Kwon, Seong‐Beom Koh
SJR Q1Journal of the Neurological Sciences
NeurologyMedicine
3
논문|인용수 50·2012
Postural Instability and Cognitive Dysfunction in Early Parkinson's Disease
Jong Moon Lee, Seong‐Beom Koh, Sung Won Chae, Woo‐Keun Seo, Do‐Young Kwon, Ji Hyun Kim, Kyungmi Oh, Jong Sam Baik, Kun Woo Park
SJR Q2Canadian Journal of Neurological Sciences / Journal Canadien des Sciences NeurologiquesOA

BACKGROUND: Postural instability is one of the most disabling features of Parkinson's disease, usually occurring in late and advanced stages. The aim of this study was to investigate the postural performance of early-stage de novo Parkinson's disease patients with no clinical postural instability using computerized dynamic posturography. We sought to understand the relationship between postural sway and disease severity and the relationship between postural instability quantitatively measured by

NeurologyMedicine
4
논문|인용수 49·2007
Clinical and laboratory characteristics of cerebral infarction in tuberculous meningitis: A comparative study
Seong‐Beom Koh, Byung‐Jo Kim, Moon Ho Park, Sung-Wook Yu, Kun Woo Park, Dae Hie Lee
SJR Q2Journal of Clinical Neuroscience
SurgeryMedicine
5
논문|인용수 41·2016
The combined effect of REM sleep behavior disorder and hyposmia on cognition and motor phenotype in Parkinson's disease
Sung Hoon Kang, Hye Mi Lee, Woo‐Keun Seo, Ji Hyun Kim, Seong‐Beom Koh
SJR Q1Journal of the Neurological Sciences
Sensory SystemsNeuroscience
6
논문|인용수 36·2015
Comparison of motor and non-motor features between essential tremor and tremor dominant Parkinson's disease
Kyum‐Yil Kwon, Hye Mi Lee, Seon-Min Lee, Sung Hoon Kang, Seong‐Beom Koh
SJR Q1Journal of the Neurological SciencesOA
NeurologyMedicine
7
논문|인용수 36·2014
Nonmotor Symptoms and Cognitive Decline in de novo Parkinson’s Disease
Kyum‐Yil Kwon, Sung Hoon Kang, Minjik Kim, Hye Mi Lee, Ji Wan Jang, Ju Yeon Kim, Seon-Min Lee, Seong‐Beom Koh
SJR Q2Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

BACKGROUND: Cognitive impairments are common in Parkinson's disease (PD). Despite its clinical importance, the development of dementia is still difficult to predict. In this study, we investigated the possible associations between non-motor symptoms and the risk of developing dementia within a 2-year observation period in PD. METHODS: A total of 80 patients with PD participated in this study. Nonmotor symptoms (the Nonmotor Symptoms Questionnaire), PD status (Unified Parkinson's Disease Rating S

NeurologyMedicine
8
논문|인용수 33·2013
The interrelationship between non-motor symptoms in Atypical Parkinsonism
Chan‐Nyoung Lee, Minjik Kim, Hye Mi Lee, Ji-Wan Jang, Seon-Min Lee, Do‐Young Kwon, Kun Woo Park, Seong‐Beom Koh
SJR Q1Journal of the Neurological Sciences
NeurologyMedicine
9
논문|인용수 33·2014
Is reduced arm and leg swing in Parkinson's disease associated with rigidity or bradykinesia?
Kyum‐Yil Kwon, Minjik Kim, Seon-Min Lee, Sung Hoon Kang, Hye Mi Lee, Seong‐Beom Koh
SJR Q1Journal of the Neurological Sciences
NeurologyMedicine
10
논문|인용수 32·2011
Stereopsis in Drug Naïve Parkinson's Disease Patients
Seung Hyun Kim, Ji‐Hye Park, Yu Hwan Kim, Seong‐Beom Koh
SJR Q2Canadian Journal of Neurological Sciences / Journal Canadien des Sciences NeurologiquesOA

BACKGROUND: Motor deficits associated with Parkinson's disease (PD) have been well described, yet little attention has been paid to non-motor symptoms, especially cortical visual dysfunction. We investigated stereopsis, as well as the relationship between stereopsis and other cognitive function, in a sample of PD patients. METHODS: We used Titmus stereotest plates for assessing stereopsis. Fifty-nine subjects (29 PD patients and 30 normal controls) were included in this study. The included patie

Endocrinology, Diabetes and MetabolismMedicine
11
논문|인용수 32·2012
Clinical characteristics of impulse control and repetitive behavior disorders in Parkinson’s disease
Ju‐Yeon Kim, Mijin Kim, Do‐Young Kwon, Woo‐Keun Seo, Ji Hyun Kim, Jong Sam Baik, Seong‐Beom Koh
SJR Q1Journal of Neurology
NeurologyMedicine
12
논문|인용수 32·2013
Stereopsis and extrastriate cortical atrophy in Parkinson’s disease
Seong‐Beom Koh, Sang‐il Suh, Seung Hyun Kim, Ji Hyun Kim
SJR Q3Neuroreport

Among the various visuospatial dysfunctions, deficits of stereopsis could be associated with Parkinson's disease. We examined differences in regional gray matter volume between Parkinson's disease patients with normal stereopsis and with abnormal stereopsis to delineate the possible anatomical correlate of stereopsis. Stereopsis was assessed using the Titmus test in 35 drug-naive patients with Parkinson's disease. Voxel-based morphometry was utilized to assess regionally specific differences in

NeurologyMedicine
13
논문|인용수 28·2017
Recuperation of slow walking in de novo Parkinson’s disease is more closely associated with increased cadence, rather than with expanded stride length
Kyum‐Yil Kwon, Hye Mi Lee, Sung Hoon Kang, Seon Jong Pyo, Han‐Jun Kim, Seong‐Beom Koh
SJR Q1Gait & Posture
NeurologyMedicine
14
논문|인용수 26·2019
Influences of elbow, shoulder, trunk motion and temporospatial parameters on arm swing asymmetry of Parkinson's disease during walking
Seong‐Beom Koh, Young-Min Park, Mi‐Jung Kim, Woo-Sub Kim
SJR Q2Human Movement Science
NeurologyMedicine
15
논문|인용수 23·2023
Incidence of Parkinson’s disease and modifiable risk factors in Korean population: A longitudinal follow-up study of a nationwide cohort
Sung Hoon Kang, Seok Joo Moon, Minwoong Kang, Su Jin Chung, Geum Joon Cho, Seong‐Beom Koh
SJR Q1Frontiers in Aging NeuroscienceOA

Introduction: We aimed to investigate the incidence of Parkinson's disease (PD) by age and year for each sex as well as the modifiable risk factors for PD. Using data from the Korean National Health Insurance Service, 938,635 PD and dementia-free participants aged ≥40 years who underwent general health examinations were followed to December 2019. Methods: We analyzed the PD incidence rates according to age, year and sex. To investigate the modifiable risk factors for PD, we used the Cox regressi

NeurologyMedicine

대표 연구 분야

NeurologyPsychiatry and Mental healthCellular and Molecular NeuroscienceEpidemiologyPhysiologySurgery

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