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윤성현 교수

Sung Hyun Yoon

성균관대학교 의학과 · 의학

연구실 소개

윤성현 교수의 연구실은 대장암의 정밀 진단 및 치료 전략 개발에 초점을 맞추고 있습니다. 특히, 병행 치료와 수술 후 생존율에 영향을 미치는 분자유전자 마커(예: KRAS 변이)와 종양 침윤 수치(종양 침윤 수)의 예후적 역할을 체계적으로 분석하고 있으며, 복강경 수술 기술의 정착과 발전을 위한 임상적 연구도 지속하고 있습니다. 이는 환자의 개인화된 치료 계획 수립과 치료 성과 향상에 기여하고자 하는 목적이 있습니다.

대장암KRAS 변이종양 침윤 수복강경 수술예후 분석

연구 현황

논문 수
316
총 인용 수
7,617
최근 5년 논문
56
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
56총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
388총합
20222023202420252026

주요 논문

15
1
논문|인용수 173·2006
Pulmonary resection for metastases from colorectal cancer: prognostic factors and survival
Won Suk Lee, Seong Hyeon Yun, Ho-Kyung Chun, Woo-Yong Lee, Hae‐Ran Yun, Jhingook Kim, Kwhanmien Kim, Young Mog Shim
SJR Q2International Journal of Colorectal Disease
HepatologyMedicine
2
논문|인용수 160·2008
Clinical Outcomes of Hepatic Resection and Radiofrequency Ablation in Patients With Solitary Colorectal Liver Metastasis
Won‐Suk Lee, Seong Hyeon Yun, Ho-Kyung Chun, Woo Yong Lee, Sung-Joo Kim, Seong‐Ho Choi, Jin-Seok Heo, Jae‐Won Joh, Dongil Choi, Seung‐Hoon Kim, Hyunchul Rhim, Hyo-Keun Lim
SJR Q2Journal of Clinical Gastroenterology

Despite of higher local recurrence rate, RFA may be considered as a therapeutic option for patients who are considered unsuitable for conventional surgical treatment. Randomized prospective controlled trials comparing the therapeutic outcome of RFA and HR are definitely warranted.

HepatologyMedicine
3
논문|인용수 154·2007
Tumor Localization for Laparoscopic Colorectal Surgery
Yong Beom Cho, Woo Yong Lee, Hae Ran Yun, Won Suk Lee, Seong Hyeon Yun, Ho‐Kyung Chun, Seong Hyeon Yun, Ho‐Kyung Chun
SJR Q1World Journal of Surgery

BACKGROUND: Because palpating colonic tumors during laparoscopy is impossible, the precise location of a tumor must be identified before operation. The aim of this study was to evaluate the accuracy of various diagnostic methods that are used to localize colorectal tumors and to propose an adequate localization protocol for laparoscopic colorectal surgery. METHODS: A total of 310 patients underwent laparoscopy-assisted colectomy between April 2000 and March 2006. We investigated if the locations

OncologyMedicine
4
논문|인용수 75·2008
Local recurrence after curative resection in patients with colon and rectal cancers
H. R. Yun, L. J. Lee, J. H. Park, Y. K. Cho, Y. B. Cho, Won‐Young Lee, H. C. Kim, Ho-Kyung Chun, Seong Hyeon Yun
SJR Q2International Journal of Colorectal Disease
OncologyMedicine
5
논문|인용수 58·2007
Risk factor stratification after simultaneous liver and colorectal resection for synchronous colorectal metastasis
Won Suk Lee, Min Jung Kim, Seong Hyeon Yun, Ho-Kyung Chun, Woo Yong Lee, Sung-Joo Kim, Seong‐Ho Choi, Jin-Seok Heo, Jae‐Won Joh, Yong Il Kim
SJR Q2Langenbeck s Archives of Surgery
HepatologyMedicine
6
논문|인용수 50·2016
The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis
Hae Su Kim, Jin Seok Heo, Jeeyun Lee, Ji Yun Lee, Min‐Young Lee, Sung Hee Lim, Woo Yong Lee, Seok Hyung Kim, Yoon Ah Park, Yong Beom Cho, Seong Hyeon Yun, Seung Tae Kim
SJR Q2BMC CancerOA

BACKGROUND: KRAS mutations are common in colorectal cancer (CRC). The role of KRAS mutation status as a prognostic factor remains controversial, and most large population-based cohorts usually consist of patients with non-metastatic CRC. We evaluated the impact of KRAS mutations on the time to recurrence (TTR) and overall survival (OS) in patients with metastatic CRC who underwent curative surgery with perioperative chemotherapy. METHODS: Patients who underwent curative resection for primary and

OncologyMedicine
7
논문|인용수 45·2013
Single-incision laparoscopic right colectomy compared with conventional laparoscopy for malignancy: assessment of perioperative and short-term oncologic outcomes
Jung-A Yun, Seong Hyeon Yun, Yoon Ah Park, Yong Beom Cho, Hee Cheol Kim, Woo Yong Lee, Ho-Kyung Chun
SJR Q1Surgical Endoscopy
SurgeryMedicine
8
논문|인용수 34·2021
Revised Nodal Staging Integrating Tumor Deposit Counts With Positive Lymph Nodes in Patients With Stage III Colon Cancer
Dae Hee Pyo, Seok Hyung Kim, Sang Yoon Ha, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Jung Kyong Shin, Woo Yong Lee, Hee Cheol Kim
SJR Q1Annals of Surgery

OBJECTIVE: We evaluated the prognostic value of tumor deposit (TD) counts and incorporated them with the number of positive lymph nodes to develop a revised nodal staging. SUMMARY BACKGROUND DATA: The current American Joint Committee on Cancer (AJCC) staging on colon cancer includes the TDs only for nodenegative patients, as N1c, and their counts are not considered. METHODS: We included consecutive patients with stage III colorectal cancer who underwent curative resections between January 2010 a

OncologyMedicine
9
논문|인용수 20·2007
Clinical Usefulness of Chest Radiography in Detection of Pulmonary Metastases After Curative Resection for Colorectal Cancer
Won Suk Lee, Seong Hyeon Yun, Ho‐Kyung Chun, Woo Yong Lee, Hae‐Ran Yun
SJR Q1World Journal of Surgery

PURPOSE: The purpose of this study was to evaluate the effectiveness of chest radiography (CXR) and abdominal computed tomography (CT) for detecting pulmonary metastases after curative surgery for colorectal cancer. METHODS: We performed a retrospective analysis of the records of all patients with pulmonary metastasis from colorectal cancer who underwent curative resection between 1994 and 2004 at our institution. RESULTS: Pulmonary metastases were detected in 193 patients by either CXR or abdom

Pulmonary and Respiratory MedicineMedicine
10
논문|인용수 17·2014
Single incision and reduced port laparoscopic low anterior resection for rectal cancer: initial experience in 96 cases
Kyung Uk Jung, Seong Hyeon Yun, Yong Beom Cho, Hee Cheol Kim, Woo Yong Lee, Ho‐Kyung Chun
SJR Q2ANZ Journal of SurgeryOA

BACKGROUND: Although a single incision laparoscopic (SIL) technique has been used increasingly in colorectal surgery, there are only a few reports on the clinical availability of this approach coupled with low anterior resection (SIL-LAR) for colorectal cancers. We report here 96 consecutive cases of SIL-LAR and reduced port LAR cases, of which the initial approach was SIL. METHODS: This is a retrospective review of prospectively collected data of SIL-LAR cases performed by a single surgeon in S

SurgeryMedicine
11
논문|인용수 15·2008
The clinical outcome and prognostic factors after multi-visceral resection for advanced colon cancer
Seong Hyeon Yun, H. R. Yun, W.S. Lee, Y.B. Cho, W.Y. Lee, H.K. Chun
SJR Q1European Journal of Surgical Oncology
OncologyMedicine
12
논문|인용수 13·2023
Single‐port laparoscopic versus single‐port robotic right hemicolectomy: Postoperative short‐term outcomes
Ji Ha Lim, Seong Hyeon Yun, Woo Yong Lee, Hee Cheol Kim, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Jung Kyong Shin
SJR Q2International Journal of Medical Robotics and Computer Assisted SurgeryOA

BACKGROUND: system and single port laparoscopic (SPL) right hemicolectomy and determine whether the novel SPR system is safe and feasible. METHODS: From January 2019 to December 2020, a total of 141 patients (41 patients for SPR and 100 patients for SPL) who electively underwent right hemicolectomy for colon cancer performed by a single surgeon were included in the study. RESULTS: The time to the first bowel movement was 3 (range, 1-4) days after surgery in the SPR group and 3 (2-9, range) days

SurgeryMedicine
13
논문|인용수 7·2018
Prognostic Role of Carcinoembryonic Antigen Level after Preoperative Chemoradiotherapy in Patients with Rectal Cancer
Jung Wook Huh, Seong Hyeon Yun, Seok Hyung Kim, Yoon Ah Park, Yong Beom Cho, Hee Cheol Kim, Woo Yong Lee, Hee Chul Park, Doo Ho Choi, Joon Oh Park, Young Suk Park, Ho-Kyung Chun
SJR Q1Journal of Gastrointestinal Surgery
OncologyMedicine
14
논문|인용수 6·2018
The Role of Hand-Assisted Laparoscopic Technique in the Age of Single-Incision Laparoscopy: An Effective Alternative to Avoid Open Conversion in Colorectal Surgery
Kyung Uk Jung, Seong Hyeon Yun, Yong Beom Cho, Hee Cheol Kim, Woo Yong Lee, Ho-Kyung Chun
SJR Q2Journal of Laparoendoscopic & Advanced Surgical Techniques

Conversion from SILS to HALS in colorectal surgery was feasible and effective. It seemed to add minimal morbidity while preserving advantages of minimally invasive surgery. It could be considered an alternative to open conversion in cases of SILS, especially when the conversion to conventional laparoscopy does not seem to be helpful.

SurgeryMedicine
15
논문|인용수 5·2023
Association Between Distress at Diagnosis and Disease-free Survival Among Patients With Resectable Colon Cancer: A Large Cohort Study
Jung Kyong Shin, Danbee Kang, Soohyun Kim, Youngeun Choi, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Juhee Cho, Hee Cheol Kim
SJR Q1Annals of Surgery

OBJECTIVE: This study aimed to evaluate the association between distress at initial diagnosis and disease-free survival in patients with resectable colon cancer. SUMMARY BACKGROUND DATA: Considerable research has examined the psychological impact of having a confirmed diagnosis of cancer, but relatively limited research has examined the impact of distress during the diagnostic phase on oncological outcomes. METHODS: This is a retrospective cohort study. We included newly diagnosed colon cancer p

OncologyMedicine

대표 연구 분야

OncologySurgeryPathology and Forensic MedicineHepatologyPulmonary and Respiratory MedicineCancer Research

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