정성민 교수
Sung-min Jeong
연세대학교 외과 · 의학
연구실 소개
정성민 교수의 연구실은 생체리듬과 건강 간의 상호작용을 중심으로 한 전통적 운동요법(Qi-training, ChunDoSunBup)의 생리적·정서적 영향을 과학적으로 분석합니다. 특히 중추성 비만, 면역 반응 조절, 심장 기능 보호 등에 대한 기전 연구를 통해 전통적 치유 방법의 현대의학적 근거를 확립하고자 합니다. 또한, 고 dielectric 상수를 가진 나노소재(CCTO)와 메모리 소자(Phase-Change Memory)의 물리적 특성에 대한 재료 및 시뮬레이션 연구도 병행하고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15Smoking was positively associated with central obesity. Current smokers should be acquainted that they may be more prone to central obesity.
The aim of this study was to investigate the influence of two acute Qigong interventions (Qi-training and Qi-therapy) on immune cells. The Qigong interventions were compared with placebo training and placebo therapy in which no attempt was made to gather or move Qi. Immune cell numbers were measured pre-intervention, immediately post-intervention and 1 or 2 hours post-intervention. White blood cells increased significantly 2 hours after actual Qi-training (p < 0.05) but not sham training compare
Protocatechuic acid (3,4-dihydroxybenzoic acid) prevents oxidative stress, inflammation and cardiac hypertrophy. This study aimed to investigate the therapeutic effects of protocatechuic acid in an isoproterenol-induced heart failure mouse model and to identify the underlying mechanisms. To establish the heart failure model, C57BL/6NTac mice were given high-dose isoproterenol (80 mg/kg body weight) for 14 days. Echocardiography revealed that protocatechuic acid reversed the isoproterenol-induced
This cross-sectional investigation evaluated the trend of psychological changes by ChunDoSunBup (CDSB) Qi-training using a self-report inventory of emotional distress, Symptom Check List-90-Revision (SCL-90-R). 41 normal healthy subjects (mean age = 20.98 +/- 5.39) and 123 CDSB Qi-trainees (divided into three groups, Q1, Q2 and Q3) participated in this study. Group Q1 has received 1-4 months CDSB Qi-training (age 21.95 +/- 7.82, n = 41); Q2 has 5-12 months Qi-training (age 20.0 +/- 7.75, n = 41)
High dielectric constant ( k ) CaCu 3 Ti 4 O 12 (CCTO) has been studied as a potential filler for low‐temperature cofired ceramics (LTCC) based on typical calcium aluminoborosilicate glass. CCTO does not appear to be chemically reactive with the glass regardless of the firing temperature over the compositional range of 30–90 wt% CCTO. Dielectric constant and dielectric loss turned out to depend strongly on the relative content of CCTO and firing temperature. As an optimal composition, the glass
The reset operation of phase-change random access memory (PRAM) was simulated by the finite element method. The dominant variables for optimizing reset operation were proved to be not only the reset current but also the shape of the formed amorphous region in the writing layer. The connection of the electrical resistances through the crystal and/or the formed amorphous region in the writing layer was found to depend on the shape of the formed amorphous region. The classical nucleation theory and
The present study investigated the effects of in vitro and in vivo Korean ChunSoo Qi-Energy Healing on neutrophil superoxide generation. Neutrophil superoxide generation was measured by a chemiluminescence assay. Superoxide generation was significantly increased in vitro by emitted Qi-therapy (QT) of 60-second duration and 150-second duration compared to control (1.59-fold for 60 seconds, p < 0.05; 1.50-fold for 150 seconds, p < 0.05). Neutrophil superoxide generation increased significantly imm
AIMS: Morton's neuroma is common condition of the forefoot, but its aetiology remains unclear. Our aim was to evaluate the relationship between the width of the forefoot and the development of a Morton's neuroma. PATIENTS AND METHODS: Between January 2013 and May 2016, a total of 84 consecutive patients (17 men, 67 women) with a unilateral Morton's neuroma were enrolled into the study. The involved and uninvolved feet of each patient were compared. A control group of patients with symptoms from
The main objective of this study is to examine the effect of Qi-training on the immune system, especially neutrophil bactericidal function. Nine healthy male subjects were studied for the effects of one bout of ChunDoSunBup (CDSB) Qi-training on superoxide (O2- production and adhesion capacity of neutrophils at times immediately after (Post I) and 2 hours after the Qi-training (Post II). The Qi-training enhanced O2- production, reaction velocity and neutrophil adhesion capacity and there were si
1. The in vitro metabolism of the new insecticide flupyrazofos was studied using rat liver microsomes. Two metabolites were produced and identified as O,O-diethyl O-(1-phenyl-3-trifluoromethyl-5-pyrazoyl) phosphoric acid ester (flupyrazofos oxon) and 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole (PTMHP) based on UV and mass spectral analysis. 2. Cytochrome P450 oxidatively converted flupyrazofos to flupyrazofos oxon, a major metabolite and phenobarbital-induced microsomes increased this desulphur
The aim of this study is to explore the effects of ChunDoSunBup Qi-training on personality traits. Twenty-six normal healthy subjects (mean age = 26.58 +/- 6.56) and 26 CDSB Qi-trainees (mean age = 27.74 +/- 5.21) participated in this study. Analysis of MMPI profiles showed that CDSB Qi-trainees scored significantly lower on Depression (D), Hysteria (Hy), Paranoia (Pa), Schizophrenia (Sc) and Frequency (F) and significantly higher on the Correction (K) Scales. In addition, CDSB Qi-trainees repor
The crucible design having a stepped wall was introduced for increasing the growth rate of SiC crystal without metal addition in top-seeded solution growth (TSSG) method. The numerical simulation confirmed that new crucible design to increase the solvent-crucible interface could definitely change the temperature distribution and increase the carbon concentration. The simulation result, SiC single crystals were grown with Si solvent at 1900°C using a normal crucible and a stepped crucible to inve
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